por
Sheppard, Carmen L.,
Groves, Natalie,
Andrews, Nicholas,
Litt, David J.,
Fry, Norman K.,
Southern, Jo,
Miller, Elizabeth
Publicado 2019
“…We used whole genome sequencing (WGS) analysis to investigate the population structure of 877 Streptococcus pneumoniae isolates from five carriage studies from 2002 (N = 346), 2010 (N = 127), 2013 (N = 153), 2016 (N = 187) and 2018 (N = 64) in UK households which covers the period pre-PCV7 to
post-PCV13 implementation. The genomic lineages seen in the population were determined using multi-locus sequence typing (MLST) and Pop
PUNK (Population Partitioning Using Nucleotide K-mers) which was used for local and global comparisons. …”
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