“…More recently, ROS have emerged as key players in normal cellular signalling by oxidising redox-sensitive cysteine residues within proteins. …”
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“…Sex differences in redox signaling in the kidney present new challenges and opportunities for understanding the physiology and pathophysiology of the kidney. …”
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“…Redox data obtained from cyclic voltammetry experiments of the Fe(II/III) oxidation of six ferrocenyl carboxylic acids is presented in this data in brief article. …”
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“…The results suggest that a cohort of oxidation-prone proteins is endowed with phase-dependent redox stability. Moreover, in forming LLPS compartments, Dopa proteins become reservoirs of chemical energy.…”
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“…For this reason, several intracellular factors, including the redox state, might directly or indirectly affect the progression and outcome of viral infection. …”
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Materias: “…Articles from the Special Issue on Redox Signalling and Cardiovascular Disease; Edited by Christopher Kevil and Yabing Chen…”
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“…Using the redox-sensitive GFP2 (roGFP2), we validated oxidizing and reducing conditions following classical and alternative activation of MΦ, while the redox status of PPARγ was determined via mass spectrometry. …”
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“…Using a combination of in situ imaging with in situ X-ray absorption spectroscopy and scanning photoemission microscopy, we reveal the relation between chemical and morphological dynamics and demonstrate that a static picture of active sites is insufficient to describe catalytic function of redox-active metal catalysts. The observed oscillatory redox dynamics provide a unique insight on phase-cooperation and a convenient and general mechanism for constant re-generation of transient active sites.…”
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“…Triggered in response to external and internal ligands in cells and animals, redox homeostasis is transmitted via signal molecules involved in defense redox mechanisms through networks of cell proliferation, differentiation, intracellular detoxification, bacterial infection, and immune reactions. …”
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“…The current review focuses on how muscle contraction and immobilization may activate or inhibit redox signalings and their impact on muscle mitochondrial homeostasis and physiologic implications.…”
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“…Redox homeostasis is regulated by critical molecules that modulate antioxidant and redox signaling (ARS) within the cell. …”
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“…In this review, we examine methods to electrochemically interrogate the various components of molecular communication using redox chemistry and to electronically control cell communication using redox electrogenetics.…”
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“…Although peptide therapeutics have been explored for decades, the successful delivery of potent peptides in vitro and in vivo remains challenging due to the poor stability, low cell permeability, and off-target effects. We developed a redox sensitive polymer-based nanocomplex which can efficiently and stably deliver the peptide drug melittin for cancer therapy. …”
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“…Our approach identifies redox as an acute regulator of the greater metabolic network. …”
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“…Here, we explain how the key redox chemistry underlying metabolisms provides a path towards this goal. …”
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“…Redox reactions are of high fundamental and practical interest since they are involved in both normal physiology and the pathogenesis of various diseases. …”
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“…This can inactivate several of the intracellular molecules involved in epigenetic and redox regulations, thereby increasing oxidative stress giving rise to growth advantages for cancerous cells. …”
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