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4881por Vida, Carmen, Martinez de Toda, Irene, Garrido, Antonio, Carro, Eva, Molina, José Antonio, De la Fuente, Mónica“…Although AD is accompanied by systemic disturbance, reflecting the damage in the brain, the changes in immune response and redox-state in different types of blood cells in AD patients have been scarcely studied. …”
Publicado 2018
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4882por Hirayama, Aki, Oowada, Shigeru, Ito, Hiromu, Matsui, Hirofumi, Ueda, Atsushi, Aoyagi, Kazumasa“…To clarify the clinical significance of the redox-controlling effects of Kampo, a traditional Japanese herbal medicine, we determined the scavenging activities of various reactive oxygen species in clinically used Kampo formulae using an electron spin resonance-based technique. …”
Publicado 2018
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4883por Lu, Yun-Xin, Wu, Qi-Nian, Chen, Dong-liang, Chen, Le-Zong, Wang, Zi-Xian, Ren, Chao, Mo, Hai-yu, Chen, Ya, Sheng, Hui, Wang, Ying-Nan, Wang, Yun, Lu, Jia-Huan, Wang, De-shen, Zeng, Zhao-lei, Wang, Feng, Wang, Feng-Hua, Li, Yu-Hong, Ju, Huai-Qiang, Xu, Rui-HuaEnlace del recurso
Publicado 2018
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4884por Nguyen, Anh Khoa, Nguyen, Thi Hiep, Bao, Bui Quoc, Bach, Long Giang, Nguyen, Dai Hai“…In this report, PNS was surface conjugated with adamantylamine (ADA) via disulfide bridges (-SS-), PNS-SS-ADA, which was further modified with cyclodextrin-poly(ethylene glycol) methyl ether conjugate (CD-mPEG) to form a core@shell structure PNS-SS-ADA@CD-mPEG for redox triggered delivery of doxorubicin (DOX), DOX/PNS-SS-ADA@CD-mPEG. …”
Publicado 2018
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4885por Song, Yu, Cai, Han, Yin, Tingjie, Huo, Meirong, Ma, Ping, Zhou, Jianping, Lai, Wenfang“…BACKGROUND: Lung cancer is the primary cause of cancer-related death worldwide. A redox-sensitive nanocarrier system was developed for tumor-targeted drug delivery and sufficient drug release of the chemotherapeutic agent paclitaxel (PTX) for improved lung cancer treatment. …”
Publicado 2018
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4886por Ma, Tianyi, Yoo, Mi‐Jeong, Zhang, Tong, Liu, Lihong, Koh, Jin, Song, Wen‐Yuan, Harmon, Alice C., Sha, Wei, Chen, Sixue“…Collectively, these data provide detailed biochemical characterization of redox‐induced modifications and changes of the BnSnRK2.6‐2C activity.…”
Publicado 2018
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4887por Hollinshead, Kate E.R., Munford, Haydn, Eales, Katherine L., Bardella, Chiara, Li, Chunjie, Escribano-Gonzalez, Cristina, Thakker, Alpesh, Nonnenmacher, Yannic, Kluckova, Katarina, Jeeves, Mark, Murren, Robert, Cuozzo, Federica, Ye, Dan, Laurenti, Giulio, Zhu, Wei, Hiller, Karsten, Hodson, David J., Hua, Wei, Tomlinson, Ian P., Ludwig, Christian, Mao, Ying, Tennant, Daniel A.“…One aspect of the neomorphic function of the IDH1 R132H enzyme that has received less attention is the perturbation of cellular redox homeostasis. Here, we describe a biosynthetic pathway exhibited by cells expressing mutant IDH1. …”
Publicado 2018
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4888por Idiris, Fahima I. M., Majesté, Cécile E., Craven, Gregory B., Jones, Christopher R.“…This unique transformation is utilized in redox-neutral intermolecular α-functionalization reactions of different tertiary amines, generating C(sp(3))–C(sp(3)/sp(2)/sp) bonds in a single synthetic operation. …”
Publicado 2018
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4889por Chang, Soyoung, Kilic, Tugba, Lee, Chang Kee, Avci, Huseyin, Bae, Hojae, Oskui, Shirin Mesbah, Jung, Sung Mi, Shin, Su Ryon, Kim, Seon Jeong“…We observed reversible electrochemical redox activity upon external stimuli in a quick and robust manner. …”
Publicado 2018
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4890“…In addition to its biological roles, this review also focuses on the dual functions of STRAP in cancers displaying redox dysregulation, where it can behave as a tumor suppressor or an oncogene (i.e., it can either inhibit or promote tumor formation), depending on the cellular context. …”
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4891por Zheng, Ping, Pu, Bei, Yu, Bing, He, Jun, Yu, Jie, Mao, Xiangbing, Luo, Yuheng, Luo, Junqiu, Huang, Zhiqing, Luo, Chenggui, Wang, Shaohui, Chen, DaiwenEnlace del recurso
Publicado 2018
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4892“…Cancer cells often upregulate nutrient transporters to fulfill their increased biosynthetic and bioenergetic needs, and to maintain redox homeostasis. One nutrient transporter frequently overexpressed in human cancers is the cystine/glutamate antiporter solute carrier family 7 member 11 (SLC7A11; also known as xCT). …”
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4893por Yang, Lin, He, Zihao, Yao, Jingyue, Tan, Renxiang, Zhu, Yejin, Li, Zhiyu, Guo, Qinglong, Wei, Libin“…The reprogram of glycolipid metabolism destroyed the redox balance ultimately and induced cell death. …”
Publicado 2018
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4894por Leblanc, Nicolas, Sproules, Stephen, Fink, Karin, Sanguinet, Lionel, Alévêque, Olivier, Levillain, Eric, Rosa, Patrick, Powell, Annie K.“…To intimately combine a chelating ligand function with the numerous properties of a viologen-like redox-active centre would offer a rare possibility to design controllable multi-redox states, whose properties arise from strongly correlated phenomena between the organic ligand as well as with any metalloid coordinated centres. …”
Publicado 2016
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4895“…The metal-anchorable sulfur atom, the strong π-coordinating iron atom, the favorable redox properties, low cost, and natural abundance make Fe-S an excellent electron-mediating relay capable of wiring redox active sites to electrode surfaces. …”
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4896por Tamošiūnė, Inga, Stanienė, Gražina, Haimi, Perttu, Stanys, Vidmantas, Rugienius, Rytis, Baniulis, Danas“…Modulation of the cellular redox balance was monitored in the apple cells using a 2′,7′-dichlorodihydrofluorescein diacetate (H(2)DCFDA) probe, and strain-specific effects were observed that correlated with the in vitro shoot development results. …”
Publicado 2018
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4897por Herbet, Mariola, Szopa, Aleksandra, Serefko, Anna, Wośko, Sylwia, Gawrońska-Grzywacz, Monika, Izdebska, Magdalena, Piątkowska-Chmiel, Iwona, Betiuk, Paulina, Poleszak, Ewa, Dudka, Jarosław“…Co-administration of CPT with imipramine, such as imipramine alone, decreased the NADP+ and LPO concentrations and increased the GSH/GSSG ratio in comparison to the control, which may confirm beneficial – but comparable to imipramine – effect on redox balance under environmental stress conditions. …”
Publicado 2018
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4898por Ferreira, Caroline M., Stiebler, Renata, Saraiva, Francis M., Lechuga, Guilherme C., Walter-Nuno, Ana Beatriz, Bourguignon, Saulo C., Gonzalez, Marcelo S., Azambuja, Patrícia, Gandara, Ana Caroline P., Menna-Barreto, Rubem F. S., Paiva-Silva, Gabriela O., Paes, Marcia C., Oliveira, Marcus F.“…Here, we demonstrate that selective blockage of heme crystallization in vivo by the antimalarial drug quinidine, caused systemic heme overload and redox imbalance in distinct insect tissues, assessed by spectrophotometry and fluorescence microscopy. …”
Publicado 2018
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4899por Rossetti, Andrea C, Paladini, Maria Serena, Colombo, Martina, Gruca, Piotr, Lason-Tyburkiewicz, Magdalena, Tota-Glowczyk, Katarzyna, Papp, Mariusz, Riva, Marco A, Molteni, Raffaella“…In this context, parvalbumin-positive GABAergic interneurons, which are critically involved in processing complex cognitive tasks, are particularly vulnerable to stress exposure, an effect that may be the consequence of dysregulated redox mechanisms. METHODS: Adult Male Wistar rats were subjected to the chronic mild stress procedure for 7 weeks. …”
Publicado 2018
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4900“…Therefore, the aim of this study was the evaluation of redox homeostasis and oxidative damage in the hypothalamus and cerebral cortex of insulin-resistant and control rats. 16 male Wistar rats were divided into two equal groups (n = 8): the control and high fat diet group (HFD). …”
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