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4981por Sun, Tingli, Dong, Wenpeng, Jiang, Guohong, Yang, Jingbo, Liu, Jizhang, Zhao, Lijie, Ma, PeilongEnlace del recurso
Publicado 2020
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4982por De Virgiliis, Francesco, Hutson, Thomas H., Palmisano, Ilaria, Amachree, Sarah, Miao, Jian, Zhou, Luming, Todorova, Rositsa, Thompson, Richard, Danzi, Matt C., Lemmon, Vance P., Bixby, John L., Wittig, Ilka, Shah, Ajay M., Di Giovanni, Simone“…Mechanistically, we established that enriched conditioning relies on the unique neuronal intrinsic signaling axis PKC-STAT3-NADPH oxidase 2 (NOX2), enhancing redox signaling as shown by redox proteomics in DRG. …”
Publicado 2020
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4983“…In recent years it was shown that redox‐active guanidines are capable PCET reagents for the selective oxidation of organic molecules. …”
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4984por Gómez-Barroso, Mariana, Moreno-Calderón, Koré M., Sánchez-Duarte, Elizabeth, Cortés-Rojo, Christian, Saavedra-Molina, Alfredo, Rodríguez-Orozco, Alain R., Montoya-Pérez, Rocío“…Results showed that the treatment with diazoxide and exercise improved muscular contraction, showing an increase in maximum tension and total tension due to decreased ROS and lipid peroxidation levels and improved glutathione redox state. Therefore, these results suggest that diazoxide and exercise improve muscle function during obesity, possibly through its effects as K(ATP) channel openers.…”
Publicado 2020
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4985por Yang, Huan, Lundbäck, Peter, Ottosson, Lars, Erlandsson-Harris, Helena, Venereau, Emilie, Bianchi, Marco E., Al-Abed, Yousef, Andersson, Ulf, Tracey, Kevin J., Antoine, Daniel J.Enlace del recurso
Publicado 2020
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4986por Mackei, Máté, Vörösházi, Júlia, Sebők, Csilla, Neogrády, Zsuzsanna, Mátis, Gábor, Jerzsele, Ákos“…Since available data regarding the antioxidant activity of FWGE are limited, the aim of our study was to investigate its effects on the cellular redox homeostasis applying primary hepatocyte cell cultures of rat origin. …”
Publicado 2020
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4987por Micheli, Lucia, Collodel, Giulia, Moretti, Elena, Noto, Daria, Menchiari, Andrea, Cerretani, Daniela, Crispino, Sergio, Signorini, Cinzia“…We investigated the role of redox-imbalance in neuronal damage by a relative low dose of Docetaxel (DTX). …”
Publicado 2021
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4988por Go, Simei, Kramer, Thorquil T., Verhoeven, Arthur J., Oude Elferink, Ronald P. J., Chang, Jung-Chin“…In addition, imposing a high extracellular lactate-to-pyruvate ratio in media reduces the cytosolic NADH/NAD(+) redox state and protects against Raptinal-induced apoptosis. …”
Publicado 2020
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4989“…METHODS: The tumour-targeted and redox-responsive mesoporous silica nanoparticles (MSNs) functionalised with DNA aptamers (AS1411) as a co-delivery system was developed and investigated for the potential against metastatic breast cancer. …”
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4990por Lu, Yipin, Li, Yingrui, Sun, Yongjuan, Ma, Shuhua, Zhang, Kai, Tang, Xue, Chen, Ailing“…Consequently, the ability of OR rats to resist obesity may be attributed to their ability to maintain mitochondrial function and redox balance.…”
Publicado 2021
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4991por Blottner, Dieter, Capitanio, Daniele, Trautmann, Gabor, Furlan, Sandra, Gambara, Guido, Moriggi, Manuela, Block, Katharina, Barbacini, Pietro, Torretta, Enrica, Py, Guillaume, Chopard, Angèle, Vida, Imre, Volpe, Pompeo, Gelfi, Cecilia, Salanova, Michele“…Increased nitrosative redox homeostasis and decreased antioxidant defense response were found in post-BR control (Placebo, n = 10) vs. the antioxidant cocktail treated group (Treatment, n = 10). …”
Publicado 2021
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4992por Song, Liang, Shi, Jun-Yan, Duan, Shou-Fu, Han, Da-Yong, Li, Kuan, Zhang, Ri-Peng, He, Peng-Yu, Han, Pei-Jie, Wang, Qi-Ming, Bai, Feng-Yan“…We then analyzed transcriptomes of selected heterotic and depressed F1 hybrids and their parents growing at 40°C and found that genes associated with one-carbon metabolism and related pathways were generally up-regulated in the heterotic F1 hybrids, leading to improved cellular redox homeostasis at high temperature. Consistently, genes related with DNA repair, stress responses, and ion homeostasis were generally down-regulated in the heterotic F1 hybrids. …”
Publicado 2021
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4993por Inacio, Job D. F., Fonseca, Myslene S., Limaverde-Sousa, Gabriel, Tomas, Ana M., Castro, Helena, Almeida-Amaral, Elmo E.“…Third, we found that the leishmanicidal effect and the elevated H(2)O(2) levels induced by of EGCG can be abolished by PEG-catalase, strongly suggesting that this flavonoid kills L. infantum promastigotes by disturbing their intracellular redox balance. Finally, we gathered in silico and in vitro evidence that EGCG binds to trypanothione reductase (TR), a central enzyme of the redox homeostasis of Leishmania, acting as a competitive inhibitor of its trypanothione substrate.…”
Publicado 2021
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4994por Addison, Rachel, Weatherhead, Sophie C., Pawitri, Anandika, Smith, Graham R., Rider, Ashley, Grantham, Henry J., Cockell, Simon J., Reynolds, Nick J.“…Consistent with these findings, top transcriptional regulators of 311 nm UVB DEGs related to: a) apoptosis, DNA damage response and cell cycle control; b) innate/acquired immune regulation and inflammation; c) hypoxia/redox response and angiogenesis; d) circadian rhythmicity; f) EGR/AP1 signalling and keratinocyte differentiation; and g) mitochondrial biogenesis. …”
Publicado 2021
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4995por Valiulienė, Giedrė, Vitkevičienė, Aida, Skliutė, Giedrė, Borutinskaitė, Veronika, Navakauskienė, Rūta“…In summary, we show that modulation of redox-stress could have a potential anticancer activity in AML cells.…”
Publicado 2021
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4996por Cai, Zhaohua, Wang, Zi, Yuan, Ruosen, Cui, Mingli, Lao, Yimin, Wang, Ying, Nie, Peng, Shen, Linghong, Yi, Jing, He, Ben“…Previous studies demonstrate that SENP3, a redox-sensitive SUMO2/3-specific protease, is strongly implicated in cancer development and progression. …”
Publicado 2021
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4997“…Significant increases in blood glucose level and rat’s glucose metabolism were related to a more oxidized cellular redox state and variations in insulin and glucagon secretion. …”
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4998por Bellafiore, Marianna, Pintaudi, Anna Maria, Thomas, Ewan, Tesoriere, Luisa, Bianco, Antonino, Cataldo, Angelo, Cerasola, Dario, Traina, Marcello, Livrea, Maria Antonia, Palma, Antonio“…BACKGROUND: The aim of this study was to investigate if the supplementation with Opuntia ficus-indica (OFI) juice may affect plasma redox balance and heart rate variability (HRV) parameters following a maximal effort test, in young physically active women. …”
Publicado 2021
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4999por Dąbkowski, Kamil, Kreft, Ewelina, Sałaga‐Zaleska, Kornelia, Chyła, Gabriela, Kuchta, Agnieszka, Jankowski, Maciej“…The results suggest the important role of redox balance in the extracellular nucleotide regulation of the renal vasculature and glomerular injury in hypercholesterolemia.…”
Publicado 2021
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5000“…SIMPLE SUMMARY: We studied oncogenic processes that characterize human breast cancer (infiltrating ductal carcinoma (IDC)) and human brain tumors: glioma, astrocytoma and medulloblastoma, based on the quantification of cytochrome redox status by exploiting the resonance-enhancement effect of Raman scattering. …”
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