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  1. 1121
    “…METHODOLOGY/PRINCIPAL FINDINGS: Using cell models of familial prion disorders, we demonstrate that exposure of cells expressing normal prion protein (PrP(C)) or mutant PrP forms to a source of redox-iron induces aggregation of PrP(C) and specific mutant PrP forms. …”
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  2. 1122
  3. 1123
    “…Albumin represents the predominant circulating antioxidant agent in plasma exposed to continuous oxidative stress and a change in serum albumin structure accounts for its antioxidant properties. Alterations in the redox status of albumin may result in impairments of its biological properties. …”
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  4. 1124
    por Packer, Lester, Cadenas, Enrique
    Publicado 2011
    “…Lipoic acid non-covalently bound and exogenously administered to cells or supplemented in the diet is a potent modulator of the cell’s redox status. The diversity of beneficial effects of lipoic acid in a variety of tissues can be mechanistically viewed in terms of thiol/disulfide exchange reactions that modulate the environment’s redox and energy status. …”
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  5. 1125
  6. 1126
    por Catalgol, Betul, Kartal Ozer, Nesrin
    Publicado 2010
    “…Redox mediated signaling mechanisms play crucial roles in the pathogenesis of several cardiovascular diseases. …”
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  7. 1127
    “…NADPH oxidase-4 (Nox4) is an important modulator of redox signaling that is inducible at the level of transcriptional expression in multiple cell types. …”
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  8. 1128
  9. 1129
    “…However, it is not known what sensor neutrophils use to detect the redox state at wounds. Here we identify the Src family kinase (SFK) Lyn as a redox sensor that mediates initial neutrophil recruitment to wounds in zebrafish larvae. …”
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  10. 1130
    “…These findings suggest that the circadian system engages in cross-talk with the cellular redox state via ROS-regulatory factors.…”
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  11. 1131
    “…The functional role of nmMHC redox regulation is suggested by the redox sensitivity of its association with actin, suggesting a role of nmMHC oxidation in cytoskeleton movement. …”
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  12. 1132
    “…OS as measured by mitochondrial redox ratio (NADH/FAD) was detectable shortly after the onset of diabetes and further increased with the duration of diabetes. …”
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  13. 1133
  14. 1134
    por White, Nicholas G, Beer, Paul D
    Publicado 2012
    “…Preliminary electrochemical studies reveal that the redox-active macrocycle is capable of sensing chloride in CH(3)CN solution.…”
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  15. 1135
    “…Feedback regulation of Ero1p through reduction and oxidation of regulatory bonds within Ero1p is essential for maintaining the proper redox balance in the ER. In this paper, we show that Pdi1p is the key regulator of Ero1p activity. …”
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  16. 1136
    por Rose, Andrew L.
    Publicado 2012
    “…Due to its ability to promote both oxidative and reductive reactions, superoxide may have a profound impact on the redox state of iron, potentially influencing iron solubility, complex speciation, and bioavailability. …”
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  17. 1137
    “…It is concluded that ADH II under aerobic conditions functions to maintain intracellular redox homeostasis and to protect the cells from endogenous hydrogen peroxide.…”
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  18. 1138
  19. 1139
    por Cardaci, Simone, Ciriolo, Maria Rosa
    Publicado 2012
    “…Moreover, we debate on the ability of these mutations to affect cellular redox state and to promote carcinogenesis by impacting on redox biology.…”
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  20. 1140
    por Tinti, Federico, Soory, Mena
    Publicado 2012
    “…The oxidative effect of nicotine was investigated using androgen biomarkers of redox status and wound healing in fibroblasts; using the antioxidant glutathione for confirmation of responses. …”
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