“…Our review summarizes current knowledge on changes to redox homeostasis, as induced by the different respiratory viruses.…”
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“…ROS, endowed with signalling properties, are mainly produced by NADPH oxidases (NOXs) at the plasma membrane, but their action also involves a complex machinery of multiple redox-sensitive protein families that differ in their subcellular localization and their activity. …”
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“…Herein we describe the design and synthesis of a redox-dependent single-molecule switch. Appending a ferrocene unit to a diphenylacetylene scaffold gives a redox-sensitive handle, which undergoes reversible one-electron oxidation, as demonstrated by cyclic voltammetry analysis. (1)H-NMR spectroscopy of the partially oxidized switch and control compounds suggests that oxidation to the ferrocenium cation induces a change in hydrogen bonding interactions that results in a conformational switch.…”
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Materias: “…Redox Pioneer #14…”
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“…MAJOR CONCLUSIONS: Thermogenesis synchronizes fuel oxidation with an acute and transient increase of mitochondrial ROS that promotes the activation of redox-sensitive thermogenic signaling cascade and UCP1. …”
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“…Reactive oxygen species (ROS) are chemically active free radicals produced by partial reduction of oxygen that can activate discrete signaling pathways or disrupt redox homeostasis depending on their concentration. …”
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“…S-nitrosylation is an emerging paradigm of redox signaling by which cells confer protection against oxidative stress.…”
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“…Increasing evidence supports the view that a tight redox regulation is crucial for CSC proliferation, tumorigenicity, therapy resistance and metastasis in many cancer types. …”
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“…This review aims to present the latest results in the area of copper-based cooperative catalysis with redox-active ligands.…”
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“…They largely determine the energy density based on their decomposition voltage and the power density from their ionic conductivity. In recent years, redox electrolytes obtained a growing interest due to an additional redox activity from electrolytes, which offers an increased charge storage capacity in SCs. …”
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“…While robust scientific evidences highlight the role of exercise-associated redox modifications in modulating gene expression through the genetic machinery, the understanding of their specific impact on epigenomic profile is still at an early stage. …”
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“…At the molecular level, experimental studies highlighted that regular vigorous exercise could reduce tumor growth by driving changes in immune system, metabolism, hormones, systemic inflammation, angiogenesis and redox status. In the present review, we describe the main redox-sensitive mechanisms mediated by exercise. …”
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“…The antioxidative defense counters overproduction of ROS with detoxifying enzymes and molecular scavengers, for instance, superoxide dismutase and glutathione, in order to restore redox homeostasis. Mutations in the redox landscape can induce carcinogenesis, whereas increased ROS production can perpetuate cancer development. …”
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“…Oxidative stress likely underlies this diminished response, but muscle redox sensors that act in regeneration have not yet been characterized. …”
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“…The aim of this study is to examine the association between redox homeostasis and the melanomagenic process. …”
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“…This review article discusses the components of redox homeostasis, including reactive chemical species, oxidative enzymes, antioxidative enzymes, and degradation products. …”
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