A drug repurposing method based on inhibition effect on gene regulatory network

por Li, Xianbin, Liao, Minzhen, Wang, Bing, Zan, Xiangzhen, Huo, Yanhao, Liu, Yue, Bao, Zhenshen, Xu, Peng, Liu, Wenbin
Publicado 2023

Delineating highly transcribed noncoding elements landscape in breast cancer

por Zhu, Wenyong, Huang, Hao, Ming, Wenlong, Zhang, Rongxin, Gu, Yu, Bai, Yunfei, Liu, Xiaoan, Liu, Hongde, Liu, Yun, Gu, Wanjun, Sun, Xiao
Publicado 2023

DBTRG: De Bruijn Trim rotation graph encoding for reliable DNA storage()

por Zhao, Yunzhu, Cao, Ben, Wang, Penghao, Wang, Kun, Wang, Bin
Publicado 2023

Featured interactome of homocysteine-inducible endoplasmic reticulum protein uncovers novel binding partners in response to ER stress

por Su, Rui, Yin, Jialing, Ruan, Xiaolan, Chen, Yanxi, Wan, Pin, Luo, Zhen
Publicado 2023

LibGENiE – A bioinformatic pipeline for the design of information-enriched enzyme libraries

por Patsch, David, Eichenberger, Michael, Voss, Moritz, Bornscheuer, Uwe T., Buller, Rebecca M.
Publicado 2023

Stability of human gut microbiome: Comparison of ecological modelling and observational approaches

por Revel-Muroz, Anastasia, Akulinin, Mikhail, Shilova, Polina, Tyakht, Alexander, Klimenko, Natalia
Publicado 2023

Family-wide analysis of integrin structures predicted by AlphaFold2

por Zhang, Heng, Zhu, Daniel S., Zhu, Jieqing
Publicado 2023

Multimodal analysis and the oncology patient: Creating a hospital system for integrated diagnostics and discovery

por Messiou, Christina, Lee, Richard, Salto-Tellez, Manuel
Publicado 2023

Bst polymerase — a humble relative of Taq polymerase

por Oscorbin, Igor, Filipenko, Maxim
Publicado 2023

Uncultured prokaryotic genomes in the spotlight: An examination of publicly available data from metagenomics and single-cell genomics

por Arikawa, Koji, Hosokawa, Masahito
Publicado 2023

Regulation of the three-dimensional chromatin organization by transposable elements in pig spleen

por Li, Yuzhuo, Fan, Hairui, Qin, Weiyun, Wang, Yejun, Chen, Shuai, Bao, Wenbin, Sun, Ming-an
Publicado 2023

Deciphering m6A dynamics at a single-base level during planarian anterior-posterior axis specification

por Chen, Liqian, Zhen, Hui, Chen, Zixin, Huang, Mujie, Mak, Daniel W., Jin, Wei, Zou, Yuxiu, Chen, Mingjie, Zheng, Mingyue, Xie, Qingqiang, Zhou, Zhongjun, Jin, Guoxiang
Publicado 2023

Enzyme-constrained metabolic model and in silico metabolic engineering of Clostridium ljungdahlii for the development of sustainable production processes

por Caivano, Antonio, van Winden, Wouter, Dragone, Giuliano, Mussatto, Solange I.
Publicado 2023

Caffeine causes cell cycle arrest at G0/G1 and increases of ubiquitinated proteins, ATP and mitochondrial membrane potential in renal cells

por Kanlaya, Rattiyaporn, Subkod, Chonnicha, Nanthawuttiphan, Supanan, Thongboonkerd, Visith
Publicado 2023

Biological informed graph neural network for tumor mutation burden prediction and immunotherapy-related pathway analysis in gastric cancer

por Liu, Chuwei, Wan, Arabella H., Liang, Heng, Sun, Lei, Li, Jiarui, Yang, Ranran, Li, Qinghai, Wu, Ruibo, Hu, Kunhua, Yang, Yuedong, Cai, Shirong, Wan, Guohui, He, Weiling
Publicado 2023

Benchmarking of human Y-chromosomal haplogroup classifiers with whole-genome and whole-exome sequence data

por García-Olivares, Víctor, Muñoz-Barrera, Adrián, Rubio-Rodríguez, Luis A., Jáspez, David, Díaz-de Usera, Ana, Iñigo-Campos, Antonio, Veeramah, Krishna R., Alonso, Santos, Thomas, Mark G., Lorenzo-Salazar, José M., González-Montelongo, Rafaela, Flores, Carlos
Publicado 2023

An immune and epigenetics-related scoring model and drug candidate prediction for hepatic carcinogenesis via dynamic network biomarker analysis and connectivity mapping

por Hu, Yuting, Zhang, Xingli, Li, Qingya, Zhou, Qianmei, Fang, Dongdong, Lu, Yiyu
Publicado 2023

W254 in furin functions as a molecular gate promoting anti-viral drug binding: Elucidation of putative drug tunneling and docking by non-equilibrium molecular dynamics

por Ridgway, Harry, Orbell, John D., Matsoukas, Minos-Timotheos, Kelaidonis, Konstantinos, Moore, Graham J., Tsiodras, Sotiris, Gorgoulis, Vasilis G., Chasapis, Christos T., Apostolopoulos, Vasso, Matsoukas, John M.
Publicado 2023

ASCARIS: Positional feature annotation and protein structure-based representation of single amino acid variations

por Cankara, Fatma, Doğan, Tunca
Publicado 2023

Thyroxine metabolite-derived 3-iodothyronamine (T1AM) and synthetic analogs as efficient suppressors of transthyretin amyloidosis

por Kim, Bokyung, Ko, Young Ho, Si, Jinbeom, Na, Jongbum, Ortore, Gabriella, Chiellini, Grazia, Kim, Jin Hae
Publicado 2023