Structures and implications of the nuclease domain of human parvovirus B19 NS1 protein

por Zhang, Yixi, Shao, Zhiwei, Gao, Yanqing, Fan, Boming, Yang, Jie, Chen, Xi, Zhao, Xin, Shao, Qiyuan, Zhang, Weizhen, Cao, Chulei, Liu, Hehua, Gan, Jianhua
Publicado 2022

Define and visualize pathological architectures of human tissues from spatially resolved transcriptomics using deep learning

por Chang, Yuzhou, He, Fei, Wang, Juexin, Chen, Shuo, Li, Jingyi, Liu, Jixin, Yu, Yang, Su, Li, Ma, Anjun, Allen, Carter, Lin, Yu, Sun, Shaoli, Liu, Bingqiang, Javier Otero, José, Chung, Dongjun, Fu, Hongjun, Li, Zihai, Xu, Dong, Ma, Qin
Publicado 2022

Deep learning-based molecular dynamics simulation for structure-based drug design against SARS-CoV-2

por Sun, Yao, Jiao, Yanqi, Shi, Chengcheng, Zhang, Yang
Publicado 2022

Using bioinformatics approaches to identify survival-related oncomiRs as potential targets of miRNA-based treatments for lung adenocarcinoma

por Liu, Chia-Hsin, Liu, Shu-Hsuan, Lai, Yo-Liang, Cho, Yi-Chun, Chen, Fang-Hsin, Lin, Li-Jie, Peng, Pei-Hua, Li, Chia-Yang, Wang, Shu-Chi, Chen, Ji-Lin, Wu, Heng-Hsiung, Wu, Min-Zu, Sher, Yuh-Pyng, Cheng, Wei-Chung, Hsu, Kai-Wen
Publicado 2022

YTLR: Extracting yeast transcription factor-gene associations from the literature using automated literature readers

por Yang, Tzu-Hsien, Wang, Chung-Yu, Tsai, Hsiu-Chun, Yang, Ya-Chiao, Liu, Cheng-Tse
Publicado 2022

Subtle structural differences of nucleotide analogs may impact SARS-CoV-2 RNA-dependent RNA polymerase and exoribonuclease activity

por Madariaga-Mazón, Abraham, Naveja, José J., Becerra, Arturo, Alberto Campillo-Balderas, José, Hernández-Morales, Ricardo, Jácome, Rodrigo, Lazcano, Antonio, Martinez-Mayorga, Karina
Publicado 2022

Elucidating the enhanced binding affinity of a double mutant SP-D with trimannose on the influenza A virus using molecular dynamics

por Li, Deng, Minkara, Mona S.
Publicado 2022

The highly conserved RNA-binding specificity of nucleocapsid protein facilitates the identification of drugs with broad anti-coronavirus activity

por Fan, Shaorong, Sun, Wenju, Fan, Ligang, Wu, Nan, Sun, Wei, Ma, Haiqian, Chen, Siyuan, Li, Zitong, Li, Yu, Zhang, Jilin, Yan, Jian
Publicado 2022

New inhibitors of cathepsin V impair tumor cell proliferation and elastin degradation and increase immune cell cytotoxicity

por Mitrović, Ana, Senjor, Emanuela, Jukić, Marko, Bolčina, Lara, Prunk, Mateja, Proj, Matic, Nanut, Milica Perišić, Gobec, Stanislav, Kos, Janko
Publicado 2022

Integrating knowledge of protein sequence with protein function for the prediction and validation of new MALT1 substrates

por Bell, Peter A., Scheuermann, Sophia, Renner, Florian, Pan, Christina L., Lu, Henry Y., Turvey, Stuart E., Bornancin, Frédéric, Régnier, Catherine H., Overall, Christopher M.
Publicado 2022

Mechanisms of antibiotic action shape the fitness landscapes of resistance mutations

por Hemez, Colin, Clarelli, Fabrizio, Palmer, Adam C., Bleis, Christina, Abel, Sören, Chindelevitch, Leonid, Cohen, Theodore, Abel zur Wiesch, Pia
Publicado 2022

The potential of a data centred approach & knowledge graph data representation in chemical safety and drug design

por Pavel, Alisa, Saarimäki, Laura A., Möbus, Lena, Federico, Antonio, Serra, Angela, Greco, Dario
Publicado 2022

Challenges in genomic analysis of model systems and primary tumors of pancreatic ductal adenocarcinoma

por Hyun, Sangyeop, Park, Daechan
Publicado 2022

RBM15 condensates modulate m(6)A modification of STYK1 to promote tumorigenesis

por Jiang, Amin, Zhang, Siwei, Wang, Xinyu, Li, Dong
Publicado 2022

Identification of new head and neck squamous cell carcinoma subtypes and development of a novel score system (PGSscore) based on variations in pathway activity between tumor and ad...

por Zhang, Yufan, Liu, Ying, Huang, Junfei, Hu, Zhiqi, Miao, Yong
Publicado 2022

Computational solutions for spatial transcriptomics

por Kleino, Iivari, Frolovaitė, Paulina, Suomi, Tomi, Elo, Laura L.
Publicado 2022

CASPIAN: A method to identify chromatin topological associated domains based on spatial density cluster()

por Gong, Haiyan, Yang, Yi, Zhang, Xiaotong, Li, Minghong, Zhang, Sichen, Chen, Yang
Publicado 2022

Exosite binding modulates the specificity of the immunomodulatory enzyme ScpA, a C5a inactivating bacterial protease

por Jain, Monica, Teçza, Malgorzata, Kagawa, Todd F., Cooney, Jakki C.
Publicado 2022

Evolution of γ chain cytokines: Mechanisms, methods and applications()

por Antczak, Magdalena, Cañete, Pablo F., Chen, Zhian, Belle, Clémence, Yu, Di
Publicado 2022

Comparative genome analysis of four Leuconostoc strains with a focus on carbohydrate-active enzymes and oligosaccharide utilization pathways

por Sharma, Anshul, Sharma, Neha, Gupta, Deepshikha, Lee, Hae-Jeung, Park, Young-Seo
Publicado 2022