Strategies for structure elucidation of small molecules based on LC–MS/MS data from complex biological samples

por Tian, Zhitao, Liu, Fangzhou, Li, Dongqin, Fernie, Alisdair R., Chen, Wei
Publicado 2022

The seen and the unseen: Molecular classification and image based-analysis of gastrointestinal cancers

por Minciuna, Corina-Elena, Tanase, Mihai, Manuc, Teodora Ecaterina, Tudor, Stefan, Herlea, Vlad, Dragomir, Mihnea P., Calin, George A., Vasilescu, Catalin
Publicado 2022

Multiple transcription auto regulatory loops can act as robust oscillators and decision-making motifs

por Murugan, Rajamanickam, Kreiman, Gabriel
Publicado 2022

Targeting N6-methyladenosine RNA modification combined with immune checkpoint Inhibitors: A new approach for cancer therapy

por Liu, Weiwei, Liu, Chaoqun, Wang, Hui, Xu, Lijun, Zhou, Jueyu, Li, Sihua, Cheng, Yu, Zhou, Rui, Zhao, Liang
Publicado 2022

Long-Timescale Simulations Revealed Critical Non-Conserved Residues of Phosphodiesterases Affecting Selectivity of BAY60-7550

por Liu, Qing, Song, Menghua, Qiu, Yue, Lai-Han Leung, Elaine, Huang, Qiang, Yao, Xiaojun
Publicado 2022

Structural communication between the GTPase Sec4p and its activator Sec2p: Determinants of GEF activity and early deformations to nucleotide release

por Felline, Angelo, Raimondi, Francesco, Gentile, Sara, Fanelli, Francesca
Publicado 2022

Association of glioma CD44 expression with glial dynamics in the tumour microenvironment and patient prognosis

por Du, Zhanxin, Wang, Yaqing, Liang, Jiaqi, Gao, Shaowei, Cai, Xiaoying, Yu, Yu, Qi, Zhihui, Li, Jing, Xie, Yubin, Wang, Zhongxing
Publicado 2022

Comprehensive analysis of tumor necrosis factor-α-inducible protein 8-like 2 (TIPE2): A potential novel pan-cancer immune checkpoint

por Bai, Kun-Hao, Zhang, Yi-Yang, Li, Xue-Ping, Tian, Xiao-Peng, Pan, Meng-Meng, Wang, Da-Wei, Dai, Yu-Jun
Publicado 2022

Angiogenesis goes computational – The future way forward to discover new angiogenic targets?

por Subramanian, Abhishek, Zakeri, Pooya, Mousa, Mira, Alnaqbi, Halima, Alshamsi, Fatima Yousif, Bettoni, Leo, Damiani, Ernesto, Alsafar, Habiba, Saeys, Yvan, Carmeliet, Peter
Publicado 2022

Revealing a novel contributing landscape of ferroptosis-related genes in Parkinson’s disease

por Jian, Xingxing, Zhao, Guihu, Chen, He, Wang, Yanhui, Li, Jinchen, Xie, Lu, Li, Bin
Publicado 2022

Investigation of early neoplastic transformation and premalignant biology using genetically engineered organoid models

por Zhao, Hua, Collet, Casey, Peng, Dongzi, Sinha, Uttam K., Lin, De-Chen
Publicado 2022

Identification of mild cognitive impairment subtypes predicting conversion to Alzheimer’s disease using multimodal data

por Kikuchi, Masataka, Kobayashi, Kaori, Itoh, Sakiko, Kasuga, Kensaku, Miyashita, Akinori, Ikeuchi, Takeshi, Yumoto, Eiji, Kosaka, Yuki, Fushimi, Yasuto, Takeda, Toshihiro, Manabe, Shirou, Hattori, Satoshi, Nakaya, Akihiro, Kamijo, Kenichi, Matsumura, Yasushi
Publicado 2022

Navigating the cellular landscape in tissue: Recent advances in defining the pathogenesis of human disease

por Chen, Helen Y., Palendira, Umaimainthan, Feng, Carl G.
Publicado 2022

First thermostable CLIP-tag by rational design applied to an archaeal O(6)-alkyl-guanine-DNA-alkyl-transferase

por Merlo, Rosa, Mattossovich, Rosanna, Genta, Marianna, Valenti, Anna, Di Mauro, Giovanni, Minassi, Alberto, Miggiano, Riccardo, Perugino, Giuseppe
Publicado 2022

Literature-based translation from synthetic lethality screening into therapeutics targets: CD82 is a novel target for KRAS mutation in colon cancer

por Yang, Hsih-Te, Chien, Ming-Yu, Chiang, Jung-Hsien, Lin, Peng-Chan
Publicado 2022

Structural interplay between DNA-shape protein recognition and supercoiling: The case of IHF

por Watson, George D., Chan, Elliot W., Leake, Mark C., Noy, Agnes
Publicado 2022

Protein–protein interaction prediction with deep learning: A comprehensive review

por Soleymani, Farzan, Paquet, Eric, Viktor, Herna, Michalowski, Wojtek, Spinello, Davide
Publicado 2022

NanoRTax, a real-time pipeline for taxonomic and diversity analysis of nanopore 16S rRNA amplicon sequencing data

por Rodríguez-Pérez, Héctor, Ciuffreda, Laura, Flores, Carlos
Publicado 2022

Interplay of starch debranching enzyme and its inhibitor is mediated by Redox-Activated SPL transcription factor

por Kadoll, Sukhjiwan K., Zhou, Zhou, Dhindsa, Rajinder, Lemaux, Peggy, Buchanan, Bob B., Singh, Jaswinder
Publicado 2022

Ferric quinate (QPLEX) interacts with the major outer membrane protein (MOMP) of Campylobacter jejuni and enters through the porin channel into the periplasmic space

por Okoye, Jennifer C., Bellamy-Carter, Jeddidiah, Oldham, Neil J., Oldfield, Neil J., Mahdavi, Jafar, Soultanas, Panos
Publicado 2022