Surface Binding Energy Landscapes Affect Phosphodiesterase Isoform-Specific Inhibitor Selectivity

por Liu, Qing, Herrmann, Andreas, Huang, Qiang
Publicado 2018

Computational drug repurposing for inflammatory bowel disease using genetic information

por Grenier, Liam, Hu, Pingzhao
Publicado 2019

Rapid Bacterial Species Delineation Based on Parameters Derived From Genome Numerical Representations

por Maderankova, Denisa, Jugas, Robin, Sedlar, Karel, Vitek, Martin, Skutkova, Helena
Publicado 2019

Molecular Structures and Mechanisms of Waterborne Biodegradable Polyurethane Nanoparticles

por Wen, Chien-Hui, Hsu, Shun-Chieh, Hsu, Shan-hui, Chang, Shu-Wei
Publicado 2018

A PDZ Protein MDA-9/Syntenin: As a Target for Cancer Therapy

por Yu, Yongsheng, Li, Shuangdi, Wang, Kai, Wan, Xiaoping
Publicado 2019

Targeting the BIR Domains of Inhibitor of Apoptosis (IAP) Proteins in Cancer Treatment

por Cossu, Federica, Milani, Mario, Mastrangelo, Eloise, Lecis, Daniele
Publicado 2019

Divaricoside Exerts Antitumor Effects, in Part, by Modulating Mcl-1 in Human Oral Squamous Cell Carcinoma Cells

por Weng, Jing-Ru, Bai, Li-Yuan, Chiu, Shih-Jiuan, Chiu, Chang-Fang, Lin, Wei-Yu, Hu, Jing-Lan, Shieh, Tzong-Ming
Publicado 2019

Bivalent Ligands for Protein Degradation in Drug Discovery

por Scheepstra, Marcel, Hekking, Koen F.W., van Hijfte, Luc, Folmer, Rutger H.A.
Publicado 2019

Radiogenomic Analysis of F-18-Fluorodeoxyglucose Positron Emission Tomography and Gene Expression Data Elucidates the Epidemiological Complexity of Colorectal Cancer Landscape

por Vlachavas, Efstathios–Iason, Pilalis, Eleftherios, Papadodima, Olga, Koczan, Dirk, Willis, Stefan, Klippel, Sven, Cheng, Caixia, Pan, Leyun, Sachpekidis, Christos, Pintzas, Alexandros, Gregoriou, Vasilis, Dimitrakopoulou-Strauss, Antonia, Chatziioannou, Aristotelis
Publicado 2019

Epidemic Models of Contact Tracing: Systematic Review of Transmission Studies of Severe Acute Respiratory Syndrome and Middle East Respiratory Syndrome

por Kwok, Kin On, Tang, Arthur, Wei, Vivian W.I., Park, Woo Hyun, Yeoh, Eng Kiong, Riley, Steven
Publicado 2019

Protein structure aids predicting functional perturbation of missense variants in SCN5A and KCNQ1

por Kroncke, Brett M., Mendenhall, Jeffrey, Smith, Derek K., Sanders, Charles R., Capra, John A., George, Alfred L., Blume, Jeffrey D., Meiler, Jens, Roden, Dan M.
Publicado 2019

Effects of Lid 1 Mutagenesis on Lid Displacement, Catalytic Performances and Thermostability of Cold-active Pseudomonas AMS8 Lipase in Toluene

por Yaacob, Norhayati, Ahmad Kamarudin, Nor Hafizah, Leow, Adam Thean Chor, Salleh, Abu Bakar, Rahman, Raja Noor Zaliha Raja Abd, Ali, Mohd Shukuri Mohamad
Publicado 2019

Revealing Gene Function and Transcription Relationship by Reconstructing Gene-Level Chromatin Interaction

por Liu, Li, Li, Qian-Zhong, Jin, Wen, Lv, Hao, Lin, Hao
Publicado 2019

Blockchain Applications in the Biomedical Domain: A Scoping Review

por Drosatos, George, Kaldoudi, Eleni
Publicado 2019

Recent Advances on the Molecular Mechanism of Cervical Carcinogenesis Based on Systems Biology Technologies

por Lin, Min, Ye, Miaomiao, Zhou, Junhan, Wang, Z. Peter, Zhu, Xueqiong
Publicado 2019

Stapled Peptides Inhibitors: A New Window for Target Drug Discovery

por Ali, Ameena M., Atmaj, Jack, Van Oosterwijk, Niels, Groves, Matthew R., Dömling, Alexander
Publicado 2019

Psychiatric Disorders and Oxidative Injury: Antioxidant Effects of Zolpidem Therapy disclosed In Silico

por Bortoli, Marco, Dalla Tiezza, Marco, Muraro, Cecilia, Pavan, Chiara, Ribaudo, Giovanni, Rodighiero, Anna, Tubaro, Cristina, Zagotto, Giuseppe, Orian, Laura
Publicado 2019

Ligand-based Pharmacophore Modeling, Virtual Screening and Molecular Docking Studies for Discovery of Potential Topoisomerase I Inhibitors

por Pal, Sourav, Kumar, Vinay, Kundu, Biswajit, Bhattacharya, Debomita, Preethy, Nagothy, Reddy, Mamindla Prashanth, Talukdar, Arindam
Publicado 2019

Herb Target Prediction Based on Representation Learning of Symptom related Heterogeneous Network

por Wang, Ning, Li, Peng, Hu, Xiaochen, Yang, Kuo, Peng, Yonghong, Zhu, Qiang, Zhang, Runshun, Gao, Zhuye, Xu, Hao, Liu, Baoyan, Chen, Jianxin, Zhou, Xuezhong
Publicado 2019

IKKα Promotes the Progression and Metastasis of Non-Small Cell Lung Cancer Independently of its Subcellular Localization

por Page, Angustias, Ortega, Alba, Alameda, Josefa P., Navarro, Manuel, Paramio, Jesús M., Saiz-Pardo, Melchor, Almeida, Edilia I., Hernández, Pilar, Fernández-Aceñero, M. Jesús, García-Fernández, Rosa A., Casanova, M. Llanos
Publicado 2019