Machine learning-assisted medium optimization revealed the discriminated strategies for improved production of the foreign and native metabolites

por Aida, Honoka, Uchida, Keisuke, Nagai, Motoki, Hashizume, Takamasa, Masuo, Shunsuke, Takaya, Naoki, Ying, Bei-Wen
Publicado 2023

The impact of pathogenic and artificial mutations on Claudin-5 selectivity from molecular dynamics simulations

por Berselli, Alessandro, Alberini, Giulio, Benfenati, Fabio, Maragliano, Luca
Publicado 2023

A coarse-grained molecular dynamics investigation on spontaneous binding of Aβ(1–40) fibrils with cholesterol-mixed DPPC bilayers

por Agrawal, Nikhil, Skelton, Adam A., Parisini, Emilio
Publicado 2023

An informatic workflow for the enhanced annotation of excretory/secretory proteins of Haemonchus contortus

por Zheng, Yuanting, Young, Neil D., Song, Jiangning, Chang, Bill C.H., Gasser, Robin B.
Publicado 2023

Metabolic reprogramming of cancer-associated fibroblasts in pancreatic cancer contributes to the intratumor heterogeneity of PET-CT

por Meng, Qingcai, Fang, Zengli, Mao, Xiaoqi, Tang, Rong, Liang, Chen, Hua, Jie, Wang, Wei, Shi, Si, Yu, Xianjun, Xu, Jin
Publicado 2023

Critical evaluation of the use of artificial data for machine learning based de novo peptide identification

por McDonnell, Kevin, Howley, Enda, Abram, Florence
Publicado 2023

The second intracellular loop of the yeast Trk1 potassium transporter is involved in regulation of activity, and interaction with 14–3-3 proteins

por Masaryk, Jakub, Kale, Deepika, Pohl, Pavel, Ruiz-Castilla, Francisco J., Zimmermannová, Olga, Obšilová, Veronika, Ramos, José, Sychrová, Hana
Publicado 2023

TRIM56 coiled-coil domain structure provides insights into its E3 ligase functions

por Lou, Xiaohua, Ma, Binbin, Zhuang, Yuan, Xiao, Xiang, Minze, Laurie J., Xing, Junji, Zhang, Zhiqiang, Li, Xian C.
Publicado 2023

Discovery of a highly efficient TylF methyltransferase via random mutagenesis for improving tylosin production

por Fan, Jingyan, Yao, Zhiming, Yan, Chaoyue, Hao, Meilin, Dai, Jun, Zou, Wenjin, Ni, Minghui, Li, Tingting, Li, Lu, Li, Shuo, Liu, Jie, Huang, Qi, Zhou, Rui
Publicado 2023

Molecular interactions of tannic acid and matrix metalloproteinases 2 and 9

por Chiang, Ya-Tang, Xiao, Yu-Bai, Hsu, Shan-hui, Chang, Shu-Wei, Chou, Chia-Ching
Publicado 2023

Sequential targeting biomimetic nano platform for enhanced mild photothermal therapy and chemotherapy of tumor

por Wang, Lianfu, Wu, Manxiang, Pan, Yuning, Xie, Dong, Hong, Chengyuan, Li, Jianbin, Ma, Xuehua, Xu, Huachun, Li, Huayu, Chen, Tianxiang, Wu, Aiguo, Li, Qiang
Publicado 2023

PRO-Simat: Protein network simulation and design tool

por Salihoglu, Rana, Srivastava, Mugdha, Liang, Chunguang, Schilling, Klaus, Szalay, Aladar, Bencurova, Elena, Dandekar, Thomas
Publicado 2023

Single-cell and spatial transcriptomics: Advances in heart development and disease applications

por Long, Xianglin, Yuan, Xin, Du, Jianlin
Publicado 2023

Gastrointestinal pan-cancer landscape of tumor matrix heterogeneity identifies biologically distinct matrix stiffness subtypes predicting prognosis and chemotherapy efficacy

por Ning, Yumei, Lin, Kun, Fang, Jun, Ding, Yang, Zhang, Zhang, Chen, Xiaojia, Zhao, Qiu, Wang, Haizhou, Wang, Fan
Publicado 2023

In vivo corneal elastography: A topical review of challenges and opportunities

por Lan, Gongpu, Twa, Michael D., Song, Chengjin, Feng, JinPing, Huang, Yanping, Xu, Jingjiang, Qin, Jia, An, Lin, Wei, Xunbin
Publicado 2023

Network-based drug repurposing for potential stroke therapy

por Wu, Qihui, Chen, Cuilan, Liu, Weihua, Zhou, Yuying, Weng, Guohu, Gu, Yong
Publicado 2023

Meta-analysis of expression and the targeting of cell adhesion associated genes in nine cancer types – A one research lab re-evaluation

por Borodins, Olegs, Broghammer, Felix, Seifert, Michael, Cordes, Nils
Publicado 2023

Comprehensive analysis of glycoprotein VI-mediated platelet activation signaling pathway for predicting pan-cancer survival and response to anti-PD-1 immunotherapy

por Chen, Shuzhao, Zhang, Limei, Chen, Lezong, Huang, Qianqian, Wang, Yun, Liang, Yang
Publicado 2023

Integrative big transcriptomics data analysis implicates crucial role of MUC13 in pancreatic cancer

por Dhasmana, Anupam, Dhasmana, Swati, Agarwal, Shivangi, Khan, Sheema, Haque, Shafiul, Jaggi, Meena, Yallapu, Murali M., Chauhan, Subhash C.
Publicado 2023

On a mechanistic impact of transmembrane tetramerization in the pathological activation of RTKs

por Polyansky, Anton A., Efremov, Roman G.
Publicado 2023