Advances in optical mapping for genomic research

por Yuan, Yuxuan, Chung, Claire Yik-Lok, Chan, Ting-Fung
Publicado 2020

Structural insights into the mechanism of RNA recognition by the N-terminal RNA-binding domain of the SARS-CoV-2 nucleocapsid phosphoprotein

por Khan, Abbas, Tahir Khan, Muhammad, Saleem, Shoaib, Junaid, Muhammad, Ali, Arif, Shujait Ali, Syed, Khan, Mazhar, Wei, Dong-Qing
Publicado 2020

Sex-specific metabolic alterations in the type 1 diabetic brain of mice revealed by an integrated method of metabolomics and mixed-model

por Jiang, Qiaoying, Xu, Hangying, Yan, Junjie, Xu, Qingqing, Zheng, Yafei, Li, Chen, Zhao, Liangcai, Gao, Hongchang, Zheng, Hong
Publicado 2020

A mutation can hide another one: Think Structural Variants!

por Miressi, Federica, Faye, Pierre-Antoine, Pyromali, Ioanna, Bourthoumieux, Sylvie, Derouault, Paco, Husson, Marie, Favreau, Frédéric, Sturtz, Franck, Magdelaine, Corinne, Lia, Anne-Sophie
Publicado 2020

An information gain-based approach for evaluating protein structure models

por Postic, Guillaume, Janel, Nathalie, Tufféry, Pierre, Moroy, Gautier
Publicado 2020

Potential clinical drugs as covalent inhibitors of the priming proteases of the spike protein of SARS-CoV-2

por Li, Qizhang, Wang, Zhiying, Zheng, Qiang, Liu, Sen
Publicado 2020

A molecular device: A DNA molecular lock driven by the nicking enzymes

por Zhang, Xiaokang, Zhang, Qiang, Liu, Yuan, Wang, Bin, Zhou, Shihua
Publicado 2020

Structural and functional properties of Antarctic fish cytoglobins-1: Cold-reactivity in multi-ligand reactions

por Giordano, Daniela, Pesce, Alessandra, Vermeylen, Stijn, Abbruzzetti, Stefania, Nardini, Marco, Marchesani, Francesco, Berghmans, Herald, Seira, Constantí, Bruno, Stefano, Javier Luque, F., di Prisco, Guido, Ascenzi, Paolo, Dewilde, Sylvia, Bolognesi, Martino, Viappiani, Cristiano, Verde, Cinzia
Publicado 2020

Boolean model of anchorage dependence and contact inhibition points to coordinated inhibition but semi-independent induction of proliferation and migration

por Guberman, Eric, Sherief, Hikmet, Regan, Erzsébet Ravasz
Publicado 2020

Unlocking COVID therapeutic targets: A structure-based rationale against SARS-CoV-2, SARS-CoV and MERS-CoV Spike

por Trigueiro-Louro, João, Correia, Vanessa, Figueiredo-Nunes, Inês, Gíria, Marta, Rebelo-de-Andrade, Helena
Publicado 2020

The SARS-CoV-2 host cell receptor ACE2 correlates positively with immunotherapy response and is a potential protective factor for cancer progression

por Zhang, Zhilan, Li, Lin, Li, Mengyuan, Wang, Xiaosheng
Publicado 2020

T cell receptor sequence clustering and antigen specificity

por Vujovic, Milena, Degn, Kristine Fredlund, Marin, Frederikke Isa, Schaap-Johansen, Anna-Lisa, Chain, Benny, Andresen, Thomas Lars, Kaplinsky, Joseph, Marcatili, Paolo
Publicado 2020

An integrative deep learning framework for classifying molecular subtypes of breast cancer

por Mohaiminul Islam, Md., Huang, Shujun, Ajwad, Rasif, Chi, Chen, Wang, Yang, Hu, Pingzhao
Publicado 2020

Predicting combinations of immunomodulators to enhance dendritic cell-based vaccination based on a hybrid experimental and computational platform

por Ahmed, Rita, Crespo, Isaac, Tuyaerts, Sandra, Bekkar, Amel, Graciotti, Michele, Xenarios, Ioannis, Kandalaft, Lana E.
Publicado 2020

Advances of super-resolution fluorescence polarization microscopy and its applications in life sciences

por Chen, Long, Chen, Xingye, Yang, Xusan, He, Chao, Wang, Miaoyan, Xi, Peng, Gao, Juntao
Publicado 2020

Designing custom CRISPR libraries for hypothesis-driven drug target discovery

por Iyer, Vaishnavi Srinivasan, Jiang, Long, Shen, Yunbing, Boddul, Sanjaykumar V., Panda, Sudeepta Kumar, Kasza, Zsolt, Schmierer, Bernhard, Wermeling, Fredrik
Publicado 2020

Polymyxin B combinations with FDA-approved non-antibiotic phenothiazine drugs targeting multi-drug resistance of Gram-negative pathogens

por Hussein, Maytham, Hu, Xiaohan, Paulin, Olivia K.A., Crawford, Simon, Tony Zhou, Qi, Baker, Mark, Schneider-Futschik, Elena K., Zhu, Yan, Li, Jian, Velkov, Tony
Publicado 2020

UMI-Gen: A UMI-based read simulator for variant calling evaluation in paired-end sequencing NGS libraries

por Sater, Vincent, Viailly, Pierre-Julien, Lecroq, Thierry, Ruminy, Philippe, Bérard, Caroline, Prieur-Gaston, Élise, Jardin, Fabrice
Publicado 2020

Toward understanding the dynamic state of 3D genome

por Shinkai, Soya, Onami, Shuichi, Nakato, Ryuichiro
Publicado 2020

Protein profiles: Biases and protocols

por Urban, Gregor, Torrisi, Mirko, Magnan, Christophe N., Pollastri, Gianluca, Baldi, Pierre
Publicado 2020