Computational strategies for single-cell multi-omics integration

por Adossa, Nigatu, Khan, Sofia, Rytkönen, Kalle T., Elo, Laura L.
Publicado 2021

Conservation of binding properties in protein models

por Egbert, Megan, Porter, Kathryn A., Ghani, Usman, Kotelnikov, Sergei, Nguyen, Thu, Ashizawa, Ryota, Kozakov, Dima, Vajda, Sandor
Publicado 2021

protGear: A protein microarray data pre-processing suite

por Mwai, Kennedy, Kibinge, Nelson, Tuju, James, Kamuyu, Gathoni, Kimathi, Rinter, Mburu, James, Chepsat, Emily, Nyamako, Lydia, Chege, Timothy, Nkumama, Irene, Kinyanjui, Samson, Musenge, Eustasius, Osier, Faith
Publicado 2021

Multiobjective heuristic algorithm for de novo protein design in a quantified continuous sequence space

por Li, Rui-Xiang, Zhang, Ning-Ning, Wu, Bin, OuYang, Bo, Shen, Hong-Bin
Publicado 2021

Computational optimization of angiotensin-converting enzyme 2 for SARS-CoV-2 Spike molecular recognition

por Di Rienzo, Lorenzo, Monti, Michele, Milanetti, Edoardo, Miotto, Mattia, Boffi, Alberto, Tartaglia, Gian Gaetano, Ruocco, Giancarlo
Publicado 2021

Assessment of transferable forcefields for protein simulations attests improved description of disordered states and secondary structure propensities, and hints at multi-protein sy...

por Abriata, Luciano A., Dal Peraro, Matteo
Publicado 2021

CRISPR/Cas9 based genome editing for targeted transcriptional control in triple-negative breast cancer

por Deepak Singh, Desh, Han, Ihn, Choi, Eun-Ha, Yadav, Dharmendra Kumar
Publicado 2021

ADP-ribosylation systems in bacteria and viruses

por Mikolčević, Petra, Hloušek-Kasun, Andrea, Ahel, Ivan, Mikoč, Andreja
Publicado 2021

Genome sequence and transcriptome profiles of pathogenic fungus Paecilomyces penicillatus reveal its interactions with edible fungus Morchella importuna

por Chen, Cheng, Fu, Rongtao, Wang, Jian, Li, Xingyue, Chen, Xiaojuan, Li, Qiang, Lu, Daihua
Publicado 2021

Representations of protein structure for exploring the conformational space: A speed–accuracy trade-off

por Postic, Guillaume, Janel, Nathalie, Moroy, Gautier
Publicado 2021

HCMB: A stable and efficient algorithm for processing the normalization of highly sparse Hi-C contact data

por Wu, Honglong, Wang, Xuebin, Chu, Mengtian, Li, Dongfang, Cheng, Lixin, Zhou, Ke
Publicado 2021

QUARTERplus: Accurate disorder predictions integrated with interpretable residue-level quality assessment scores

por Katuwawala, Akila, Ghadermarzi, Sina, Hu, Gang, Wu, Zhonghua, Kurgan, Lukasz
Publicado 2021

Codon-based indices for modeling gene expression and transcript evolution

por Bahiri-Elitzur, Shir, Tuller, Tamir
Publicado 2021

Artificial intelligence in clinical care amidst COVID-19 pandemic: A systematic review

por Adamidi, Eleni S., Mitsis, Konstantinos, Nikita, Konstantina S.
Publicado 2021

Network analysis methods for studying microbial communities: A mini review

por Matchado, Monica Steffi, Lauber, Michael, Reitmeier, Sandra, Kacprowski, Tim, Baumbach, Jan, Haller, Dirk, List, Markus
Publicado 2021

Refinement of bamboo genome annotations through integrative analyses of transcriptomic and epigenomic data

por Ma, Xuelian, Zhao, Hansheng, Yan, Hengyu, Sheng, Minghao, Cao, Yaxin, Yang, Kebin, Xu, Hao, Xu, Wenying, Gao, Zhimin, Su, Zhen
Publicado 2021

A novel bioengineered fragment peptide of Vasostatin-1 exerts smooth muscle pharmacological activities and anti-angiogenic effects via blocking VEGFR signalling pathway

por Wei, Ran, Wu, Qiushuang, Ai, Nana, Wang, Lei, Zhou, Mei, Shaw, Chris, Chen, Tianbao, Ye, Richard Dequan, Ge, Wei, Siu, Shirley W.I., Kwok, Hang Fai
Publicado 2021

Comparison of the pH- and thermally-induced fluctuations of a therapeutic antibody Fab fragment by molecular dynamics simulation

por Zhang, Cheng, Codina, Nuria, Tang, Jiazhi, Yu, Haoran, Chakroun, Nesrine, Kozielski, Frank, Dalby, Paul A.
Publicado 2021

Towards multi-label classification: Next step of machine learning for microbiome research

por Wu, Shunyao, Chen, Yuzhu, Li, Zhiruo, Li, Jian, Zhao, Fengyang, Su, Xiaoquan
Publicado 2021

DeepOmix: A scalable and interpretable multi-omics deep learning framework and application in cancer survival analysis

por Zhao, Lianhe, Dong, Qiongye, Luo, Chunlong, Wu, Yang, Bu, Dechao, Qi, Xiaoning, Luo, Yufan, Zhao, Yi
Publicado 2021