Discovery of pentapeptide-inhibitor hits targeting FKBP51 by combining computational modeling and X-ray crystallography

por Han, Jian-Ting, Zhu, Yongchang, Pan, Da-Bo, Xue, Hong-Xiang, Wang, Shuang, Peng, Yali, Liu, Huanxiang, He, Yong-Xing, Yao, Xiaojun
Publicado 2021

Survival analysis across the entire transcriptome identifies biomarkers with the highest prognostic power in breast cancer

por Győrffy, Balázs
Publicado 2021

MedProDB: A database of Mediator proteins

por Bhardwaj, Rohan, Thakur, Jitendra Kumar, Kumar, Shailesh
Publicado 2021

Conformational transitions of caspase-6 in substrate-induced activation process explored by perturbation-response scanning combined with targeted molecular dynamics

por Huang, Shuheng, Mei, Hu, Lu, Laichun, Kuang, Zuyin, Heng, Yu, Xu, Lei, Liang, Xiaoqi, Qiu, Minyao, Pan, Xianchao
Publicado 2021

MyoData: An expression knowledgebase at single cell/nucleus level for the discovery of coding-noncoding RNA functional interactions in skeletal muscle

por Corso, Davide, Chemello, Francesco, Alessio, Enrico, Urso, Ilenia, Ferrarese, Giulia, Bazzega, Martina, Romualdi, Chiara, Lanfranchi, Gerolamo, Sales, Gabriele, Cagnin, Stefano
Publicado 2021

Identify differential genes and cell subclusters from time-series scRNA-seq data using scTITANS

por Shao, Li, Xue, Rui, Lu, Xiaoyan, Liao, Jie, Shao, Xin, Fan, Xiaohui
Publicado 2021

Identification of cyclin protein using gradient boost decision tree algorithm

por Zulfiqar, Hasan, Yuan, Shi-Shi, Huang, Qin-Lai, Sun, Zi-Jie, Dao, Fu-Ying, Yu, Xiao-Long, Lin, Hao
Publicado 2021

Quantitative elucidation of associations between nucleotide identity and physicochemical properties of amino acids and the functional insight

por Jin, Yan-Ting, Jin, Tian-Yue, Zhang, Zhi-Li, Ye, Yuan-Nong, Deng, Zixin, Wang, Ju, Guo, Feng-Biao
Publicado 2021

Magnesium ions regulate mesenchymal stem cells population and osteogenic differentiation: A fuzzy agent-based modeling approach

por Nourisa, Jalil, Zeller-Plumhoff, Berit, Helmholz, Heike, Luthringer-Feyerabend, Bérengère, Ivannikov, Vladimir, Willumeit-Römer, Regine
Publicado 2021

Cryptic amyloidogenic regions in intrinsically disordered proteins: Function and disease association

por Santos, Jaime, Pallarès, Irantzu, Iglesias, Valentín, Ventura, Salvador
Publicado 2021

Mutperiod: Analysis of periodic mutation rates in nucleosomes

por Morledge-Hampton, Benjamin, Wyrick, John J.
Publicado 2021

Application of long-read sequencing to the detection of structural variants in human cancer genomes

por Sakamoto, Yoshitaka, Zaha, Suzuko, Suzuki, Yutaka, Seki, Masahide, Suzuki, Ayako
Publicado 2021

Interactions between soil compositions and the wheat root microbiome under drought stress: From an in silico to in planta perspective

por Si, Jiyeon, Froussart, Emilie, Viaene, Tom, Vázquez-Castellanos, Jorge F., Hamonts, Kelly, Tang, Lin, Beirinckx, Stien, De Keyser, Annick, Deckers, Tibby, Amery, Fien, Vandenabeele, Steven, Raes, Jeroen, Goormachtig, Sofie
Publicado 2021

Geometric construction of viral genome space and its applications

por Sun, Nan, Pei, Shaojun, He, Lily, Yin, Changchuan, He, Rong Lucy, Yau, Stephen S.-T.
Publicado 2021

New structural variations responsible for Charcot-Marie-Tooth disease: The first two large KIF5A deletions detected by CovCopCan software

por Pyromali, Ioanna, Perani, Alexandre, Nizou, Angélique, Benslimane, Nesrine, Derouault, Paco, Bourthoumieu, Sylvie, Fradin, Mélanie, Sole, Guilhem, Duval, Fanny, Gomes, Constantin, Favreau, Frédéric, Sturtz, Franck, Magdelaine, Corinne, Lia, Anne-Sophie
Publicado 2021

Engineering a new vaccine platform for heterologous antigen delivery in live-attenuated Mycobacterium tuberculosis

por Broset, Esther, Calvet Seral, Juan, Arnal, Carmen, Uranga, Santiago, Kanno, Alex I., Leite, Luciana C.C., Martín, Carlos, Gonzalo-Asensio, Jesús
Publicado 2021

Aqueous ionic liquids redistribute local enzyme stability via long-range perturbation pathways

por El Harrar, Till, Frieg, Benedikt, Davari, Mehdi D., Jaeger, Karl-Erich, Schwaneberg, Ulrich, Gohlke, Holger
Publicado 2021

Non-conventional interactions of N3 inhibitor with the main protease of SARS-CoV and SARS-CoV-2

por García-Gutiérrez, Ponciano, Zubillaga, Rafael A., Ibarra, Ilich A., Martínez, Ana, Vargas, Rubicelia, Garza, Jorge
Publicado 2021

Deciphering the mechanism of action of antitubercular compounds with metabolomics

por Sakallioglu, Isin T., Barletta, Raúl G., Dussault, Patrick H., Powers, Robert
Publicado 2021

Chirality affects cholesterol-oxysterol association in water, a computational study

por Markiewicz, Michal, Szczelina, Robert, Milanovic, Bozena, Subczynski, Witold K., Pasenkiewicz-Gierula, Marta
Publicado 2021