Activated PI3Kδ breaches multiple B cell tolerance checkpoints and causes autoantibody production

por Lau, Anthony, Avery, Danielle T., Jackson, Katherine, Lenthall, Helen, Volpi, Stefano, Brigden, Henry, Russell, Amanda J., Bier, Julia, Reed, Joanne H., Smart, Joanne M., Cole, Theresa, Choo, Sharon, Gray, Paul E., Berglund, Lucinda J., Hsu, Peter, Wong, Melanie, O’Sullivan, Michael, Boztug, Kaan, Meyts, Isabelle, Uzel, Gulbu, Notarangelo, Luigi D., Brink, Robert, Goodnow, Christopher C., Tangye, Stuart G., Deenick, Elissa K.
Publicado 2019

Mevalonate metabolism–dependent protein geranylgeranylation regulates thymocyte egress

por Du, Xingrong, Zeng, Hu, Liu, Shaofeng, Guy, Cliff, Dhungana, Yogesh, Neale, Geoffrey, Bergo, Martin O., Chi, Hongbo
Publicado 2019

Downregulation of CFIm25 amplifies dermal fibrosis through alternative polyadenylation

por Weng, Tingting, Huang, Jingjing, Wagner, Eric J., Ko, Junsuk, Wu, Minghua, Wareing, Nancy E., Xiang, Yu, Chen, Ning-Yuan, Ji, Ping, Molina, Jose G., Volcik, Kelly A., Han, Leng, Mayes, Maureen D., Blackburn, Michael R., Assassi, Shervin
Publicado 2019

Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge

por Zhao, Haiyan, Xu, Lily, Bombardi, Robin, Nargi, Rachel, Deng, Zengqin, Errico, John M., Nelson, Christopher A., Dowd, Kimberly A., Pierson, Theodore C., Crowe, James E., Diamond, Michael S., Fremont, Daved H.
Publicado 2019

Iannis Aifantis: An accidental scientist

por Houston, Stephanie
Publicado 2020

Glial tauopathy: Neurons optional?

por Walker, Lary C.
Publicado 2019

Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses

por Phad, Ganesh E., Pushparaj, Pradeepa, Tran, Karen, Dubrovskaya, Viktoriya, Àdori, Monika, Martinez-Murillo, Paola, Vázquez Bernat, Néstor, Singh, Suruchi, Dionne, Gilman, O’Dell, Sijy, Bhullar, Komal, Narang, Sanjana, Sorini, Chiara, Villablanca, Eduardo J., Sundling, Christopher, Murrell, Benjamin, Mascola, John R., Shapiro, Lawrence, Pancera, Marie, Martin, Marcel, Corcoran, Martin, Wyatt, Richard T., Karlsson Hedestam, Gunilla B.
Publicado 2019

Atlas of the human intestine

por He, Xi C., Li, Linheng
Publicado 2020

Single-cell transcriptome analysis reveals differential nutrient absorption functions in human intestine

por Wang, Yalong, Song, Wanlu, Wang, Jilian, Wang, Ting, Xiong, Xiaochen, Qi, Zhen, Fu, Wei, Yang, Xuerui, Chen, Ye-Guang
Publicado 2019

Sweetening the hallmarks of cancer: Galectins as multifunctional mediators of tumor progression

por Girotti, María Romina, Salatino, Mariana, Dalotto-Moreno, Tomás, Rabinovich, Gabriel A.
Publicado 2019

B cells are sufficient to prime the dominant CD4(+) Tfh response to Plasmodium infection

por Arroyo, E. Nicole, Pepper, Marion
Publicado 2019

Insights into the molecular mechanisms underlying the inhibition of acid-sensing ion channel 3 gating by stomatin

por Klipp, Robert C., Cullinan, Megan M., Bankston, John R.
Publicado 2020

Membrane conductances of mouse cone photoreceptors

por Ingram, Norianne T., Sampath, Alapakkam P., Fain, Gordon L.
Publicado 2020

Alternative splicing potentiates dysfunction of early-onset epileptic encephalopathy SCN2A variants

por Thompson, Christopher H., Ben-Shalom, Roy, Bender, Kevin J., George, Alfred L.
Publicado 2020

Structural mechanisms of transient receptor potential ion channels

por Cao, Erhu
Publicado 2020

How stomatin stops ASIC3 gating

por Short, Ben
Publicado 2020

Active diffusion in oocytes nonspecifically centers large objects during prophase I and meiosis I

por Colin, Alexandra, Letort, Gaëlle, Razin, Nitzan, Almonacid, Maria, Ahmed, Wylie, Betz, Timo, Terret, Marie-Emilie, Gov, Nir S., Voituriez, Raphaël, Gueroui, Zoher, Verlhac, Marie-Hélène
Publicado 2020

Untangling the contribution of Haspin and Bub1 to Aurora B function during mitosis

por Hadders, Michael A., Hindriksen, Sanne, Truong, My Anh, Mhaskar, Aditya N., Wopken, J. Pepijn, Vromans, Martijn J.M., Lens, Susanne M.A.
Publicado 2020

Probing the subcellular distribution of phosphatidylinositol reveals a surprising lack at the plasma membrane

por Zewe, James P., Miller, April M., Sangappa, Sahana, Wills, Rachel C., Goulden, Brady D., Hammond, Gerald R.V.
Publicado 2020

ALIX- and ESCRT-III–dependent sorting of tetraspanins to exosomes

por Larios, Jorge, Mercier, Vincent, Roux, Aurélien, Gruenberg, Jean
Publicado 2020