Neuronal Epac1 mediates retinal neurodegeneration in mouse models of ocular hypertension

por Liu, Wei, Ha, Yonju, Xia, Fan, Zhu, Shuang, Li, Yi, Shi, Shuizhen, Mei, Fang C., Merkley, Kevin, Vizzeri, Gianmarco, Motamedi, Massoud, Cheng, Xiaodong, Liu, Hua, Zhang, Wenbo
Publicado 2020

Tumor-derived soluble CD155 inhibits DNAM-1–mediated antitumor activity of natural killer cells

por Okumura, Genki, Iguchi-Manaka, Akiko, Murata, Rikito, Yamashita-Kanemaru, Yumi, Shibuya, Akira, Shibuya, Kazuko
Publicado 2020

The colonic macrophage transcription factor RBP-J orchestrates intestinal immunity against bacterial pathogens

por Kang, Lan, Zhang, Xiang, Ji, Liangliang, Kou, Tiantian, Smith, Sinead M., Zhao, Baohong, Guo, Xiaohuan, Pineda-Torra, Inés, Wu, Li, Hu, Xiaoyu
Publicado 2020

Transcriptional profiling identifies caspase-1 as a T cell–intrinsic regulator of Th17 differentiation

por Gao, Yajing, Deason, Krystin, Jain, Aakanksha, Irizarry-Caro, Ricardo A., Dozmorov, Igor, Coughlin, Laura A., Rauch, Isabella, Evers, Bret M., Koh, Andrew Y., Wakeland, Edward K., Pasare, Chandrashekhar
Publicado 2020

Tissue-resident macrophages in omentum promote metastatic spread of ovarian cancer

por Etzerodt, Anders, Moulin, Morgane, Doktor, Thomas Koed, Delfini, Marcello, Mossadegh-Keller, Noushine, Bajenoff, Marc, Sieweke, Michael H., Moestrup, Søren Kragh, Auphan-Anezin, Nathalie, Lawrence, Toby
Publicado 2020

Plaque-associated myeloid cells derive from resident microglia in an Alzheimer’s disease model

por Reed-Geaghan, Erin G., Croxford, Andrew L., Becher, Burkhard, Landreth, Gary E.
Publicado 2020

Activation of group 2 innate lymphoid cells alleviates aging-associated cognitive decline

por Fung, Ivan Ting Hin, Sankar, Poornima, Zhang, Yuanyue, Robison, Lisa S., Zhao, Xiuli, D’Souza, Shanti S., Salinero, Abigail E., Wang, Yue, Qian, Jiang, Kuentzel, Marcy L., Chittur, Sridar V., Temple, Sally, Zuloaga, Kristen L., Yang, Qi
Publicado 2020

Macrophage galactose lectin is critical for Kupffer cells to clear aged platelets

por Deppermann, Carsten, Kratofil, Rachel M., Peiseler, Moritz, David, Bruna A., Zindel, Joel, Castanheira, Fernanda Vargas E Silva, van der Wal, Fardau, Carestia, Agostina, Jenne, Craig N., Marth, Jamey D., Kubes, Paul
Publicado 2020

Tissue-specific pathways extrude activated ILC2s to disseminate type 2 immunity

por Ricardo-Gonzalez, Roberto R., Schneider, Christoph, Liao, Chang, Lee, Jinwoo, Liang, Hong-Erh, Locksley, Richard M.
Publicado 2020

A critical role for plasminogen in inflammation

por Baker, Sarah K., Strickland, Sidney
Publicado 2020

Sequential ubiquitination of NLRP3 by RNF125 and Cbl-b limits inflammasome activation and endotoxemia

por Tang, Juan, Tu, Sha, Lin, Guoxin, Guo, Hui, Yan, Chengkai, Liu, Qingjun, Huang, Ling, Tang, Na, Xiao, Yizhi, Pope, R. Marshall, Rajaram, Murugesan V.S., Amer, Amal O., Ahmer, Brian M., Gunn, John S., Wozniak, Daniel J., Tao, Lijian, Coppola, Vincenzo, Zhang, Liwen, Langdon, Wallace Y., Torrelles, Jordi B., Lipkowitz, Stanley, Zhang, Jian
Publicado 2020

The blood–brain barrier in health and disease: Important unanswered questions

por Profaci, Caterina P., Munji, Roeben N., Pulido, Robert S., Daneman, Richard
Publicado 2020

Drugging the microbiome

por Nagler, Cathryn R.
Publicado 2020

Mutation position is an important determinant for predicting cancer neoantigens

por Capietto, Aude-Hélène, Jhunjhunwala, Suchit, Pollock, Samuel B., Lupardus, Patrick, Wong, Jim, Hänsch, Lena, Cevallos, James, Chestnut, Yajun, Fernandez, Ajay, Lounsbury, Nicolas, Nozawa, Tamaki, Singh, Manmeet, Fan, Zhiyuan, de la Cruz, Cecile C., Phung, Qui T., Taraborrelli, Lucia, Haley, Benjamin, Lill, Jennie R., Mellman, Ira, Bourgon, Richard, Delamarre, Lélia
Publicado 2020

β2-adrenergic signals downregulate the innate immune response and reduce host resistance to viral infection

por Wieduwild, Elisabeth, Girard-Madoux, Mathilde J., Quatrini, Linda, Laprie, Caroline, Chasson, Lionel, Rossignol, Rafaëlle, Bernat, Claire, Guia, Sophie, Ugolini, Sophie
Publicado 2020

Essential cell-extrinsic requirement for PDIA6 in lymphoid and myeloid development

por Choi, Jin Huk, Zhong, Xue, Zhang, Zhao, Su, Lijing, McAlpine, William, Misawa, Takuma, Liao, Tzu-Chieh, Zhan, Xiaoming, Russell, Jamie, Ludwig, Sara, Li, Xiaohong, Tang, Miao, Anderton, Priscilla, Moresco, Eva Marie Y., Beutler, Bruce
Publicado 2020

Unfolding innate mechanisms in the cancer microenvironment: The emerging role of the mesenchyme

por Koliaraki, Vasiliki, Henriques, Ana, Prados, Alejandro, Kollias, George
Publicado 2020

Cell-intrinsic adrenergic signaling controls the adaptive NK cell response to viral infection

por Diaz-Salazar, Carlos, Bou-Puerto, Regina, Mujal, Adriana M., Lau, Colleen M., von Hoesslin, Madlaina, Zehn, Dietmar, Sun, Joseph C.
Publicado 2020

Microglia in Alzheimer’s disease: Local heroes!

por Villacampa, Nàdia, Heneka, Michael T.
Publicado 2020

The omentum, a niche for premetastatic ovarian cancer

por Ma, Xiaojing
Publicado 2020