ULK complex organization in autophagy by a C-shaped FIP200 N-terminal domain dimer

por Shi, Xiaoshan, Yokom, Adam L., Wang, Chunxin, Young, Lindsey N., Youle, Richard J., Hurley, James H.
Publicado 2020

Structural insights into G domain dimerization and pathogenic mutation of OPA1

por Yu, Caiting, Zhao, Jinghua, Yan, Liming, Qi, Yuanbo, Guo, Xiangyang, Lou, Zhiyong, Hu, Junjie, Rao, Zihe
Publicado 2020

The cell biology of inflammation: From common traits to remarkable immunological adaptations

por Weavers, Helen, Martin, Paul
Publicado 2020

Stress-induced phosphorylation of CLIP-170 by JNK promotes microtubule rescue

por Henrie, Hélène, Bakhos-Douaihy, Dalal, Cantaloube, Isabelle, Pilon, Antoine, Talantikite, Maya, Stoppin-Mellet, Virginie, Baillet, Anita, Poüs, Christian, Benoit, Béatrice
Publicado 2020

A PI3K-WIPI2 positive feedback loop allosterically activates LC3 lipidation in autophagy

por Fracchiolla, Dorotea, Chang, Chunmei, Hurley, James H., Martens, Sascha
Publicado 2020

LUZP1 and the tumor suppressor EPLIN modulate actin stability to restrict primary cilia formation

por Gonçalves, João, Sharma, Amit, Coyaud, Étienne, Laurent, Estelle M.N., Raught, Brian, Pelletier, Laurence
Publicado 2020

UBR E3 ligases and the PDIA3 protease control degradation of unfolded antibody heavy chain by ERAD

por Tang, Danming, Sandoval, Wendy, Lam, Cynthia, Haley, Benjamin, Liu, Peter, Xue, Di, Roy, Deepankar, Patapoff, Tom, Louie, Salina, Snedecor, Brad, Misaghi, Shahram
Publicado 2020

Building the lipid droplet assembly complex

por Goodman, Joel M.
Publicado 2020

RIM-binding protein couples synaptic vesicle recruitment to release sites

por Petzoldt, Astrid G., Götz, Torsten W.B., Driller, Jan Heiner, Lützkendorf, Janine, Reddy-Alla, Suneel, Matkovic-Rachid, Tanja, Liu, Sunbin, Knoche, Elena, Mertel, Sara, Ugorets, Vladimir, Lehmann, Martin, Ramesh, Niraja, Beuschel, Christine Brigitte, Kuropka, Benno, Freund, Christian, Stelzl, Ulrich, Loll, Bernhard, Liu, Fan, Wahl, Markus C., Sigrist, Stephan J.
Publicado 2020

A modified lysosomal organelle mediates nonlytic egress of reovirus

por Fernández de Castro, Isabel, Tenorio, Raquel, Ortega-González, Paula, Knowlton, Jonathan J., Zamora, Paula F., Lee, Christopher H., Fernández, José J., Dermody, Terence S., Risco, Cristina
Publicado 2020

Seipin and Nem1 establish discrete ER subdomains to initiate yeast lipid droplet biogenesis

por Choudhary, Vineet, El Atab, Ola, Mizzon, Giulia, Prinz, William A., Schneiter, Roger
Publicado 2020

Neuronal activity disrupts myelinated axon integrity in the absence of NKCC1b

por Marshall-Phelps, Katy L.H., Kegel, Linde, Baraban, Marion, Ruhwedel, Torben, Almeida, Rafael G., Rubio-Brotons, Maria, Klingseisen, Anna, Benito-Kwiecinski, Silvia K., Early, Jason J., Bin, Jenea M., Suminaite, Daumante, Livesey, Matthew R., Möbius, Wiebke, Poole, Richard J., Lyons, David A.
Publicado 2020

Mitochondrial DNA segregation and replication restrict the transmission of detrimental mutation

por Chen, Zhe, Wang, Zong-Heng, Zhang, Guofeng, Bleck, Christopher K.E., Chung, Dillon J., Madison, Grey P., Lindberg, Eric, Combs, Christian, Balaban, Robert S., Xu, Hong
Publicado 2020

Rab18 regulates focal adhesion dynamics by interacting with kinectin-1 at the endoplasmic reticulum

por Guadagno, Noemi Antonella, Margiotta, Azzurra, Bjørnestad, Synne Arstad, Haugen, Linda Hofstad, Kjos, Ingrid, Xu, Xiaochun, Hu, Xian, Bakke, Oddmund, Margadant, Felix, Progida, Cinzia
Publicado 2020

A polybasic domain in aPKC mediates Par6-dependent control of membrane targeting and kinase activity

por Dong, Wei, Lu, Juan, Zhang, Xuejing, Wu, Yan, Lettieri, Kaela, Hammond, Gerald R., Hong, Yang
Publicado 2020

Stress sensor Ire1 deploys a divergent transcriptional program in response to lipid bilayer stress

por Ho, Nurulain, Yap, Wei Sheng, Xu, Jiaming, Wu, Haoxi, Koh, Jhee Hong, Goh, Wilson Wen Bin, George, Bhawana, Chong, Shu Chen, Taubert, Stefan, Thibault, Guillaume
Publicado 2020

Ubiquitin links smoothened to intraflagellar transport to regulate Hedgehog signaling

por Desai, Paurav B., Stuck, Michael W., Lv, Bo, Pazour, Gregory J.
Publicado 2020

Phosphoregulation provides specificity to biomolecular condensates in the cell cycle and cell polarity

por Gerbich, Therese M., McLaughlin, Grace A., Cassidy, Katelyn, Gerber, Scott, Adalsteinsson, David, Gladfelter, Amy S.
Publicado 2020

Blocking inflammation on the way: Rationale for CXCR2 antagonists for the treatment of COVID-19

por Koenig, Lars M., Boehmer, Daniel F.R., Metzger, Philipp, Schnurr, Max, Endres, Stefan, Rothenfusser, Simon
Publicado 2020

Neutrophils and COVID-19: Nots, NETs, and knots

por Nathan, Carl
Publicado 2020