Targeting CLK3 inhibits the progression of cholangiocarcinoma by reprogramming nucleotide metabolism

por Zhou, Qingxin, Lin, Meihua, Feng, Xing, Ma, Fei, Zhu, Yuekun, Liu, Xing, Qu, Chao, Sui, Hong, Sun, Bei, Zhu, Anlong, Zhang, Heng, Huang, He, Gao, Zhi, Zhao, Yongxiang, Sun, Jiangyun, Bai, Yuxian, Jin, Junfei, Hong, Xuehui, Zou, Chang, Zhang, Zhiyong
Publicado 2020

Retrograde migration supplies resident memory T cells to lung-draining LN after influenza infection

por Stolley, J. Michael, Johnston, Timothy S., Soerens, Andrew G., Beura, Lalit K., Rosato, Pamela C., Joag, Vineet, Wijeyesinghe, Sathi P., Langlois, Ryan A., Osum, Kevin C., Mitchell, Jason S., Masopust, David
Publicado 2020

NK cell receptor NKG2D enforces proinflammatory features and pathogenicity of Th1 and Th17 cells

por Babic, Marina, Dimitropoulos, Christoforos, Hammer, Quirin, Stehle, Christina, Heinrich, Frederik, Sarsenbayeva, Assel, Eisele, Almut, Durek, Pawel, Mashreghi, Mir-Farzin, Lisnic, Berislav, Van Snick, Jacques, Löhning, Max, Fillatreau, Simon, Withers, David R., Gagliani, Nicola, Huber, Samuel, Flavell, Richard A., Polic, Bojan, Romagnani, Chiara
Publicado 2020

Circulating tumor cells: Ready for translation?

por Diamantopoulou, Zoi, Castro-Giner, Francesc, Aceto, Nicola
Publicado 2020

Talin1 sets the stage for dendritic cell activation

por Clausen, Björn E.
Publicado 2020

Accumulation of long-chain fatty acids in the tumor microenvironment drives dysfunction in intrapancreatic CD8(+) T cells

por Manzo, Teresa, Prentice, Boone M., Anderson, Kristin G., Raman, Ayush, Schalck, Aislyn, Codreanu, Gabriela S., Nava Lauson, Carina B., Tiberti, Silvia, Raimondi, Andrea, Jones, Marissa A., Reyzer, Michelle, Bates, Breanna M., Spraggins, Jeffrey M., Patterson, Nathan H., McLean, John A., Rai, Kunal, Tacchetti, Carlo, Tucci, Sara, Wargo, Jennifer A., Rodighiero, Simona, Clise-Dwyer, Karen, Sherrod, Stacy D., Kim, Michael, Navin, Nicholas E., Caprioli, Richard M., Greenberg, Philip D., Draetta, Giulio, Nezi, Luigi
Publicado 2020

Distinct fibroblast functional states drive clinical outcomes in ovarian cancer and are regulated by TCF21

por Hussain, Ali, Voisin, Veronique, Poon, Stephanie, Karamboulas, Christina, Bui, Ngoc Hoang Bao, Meens, Jalna, Dmytryshyn, Julia, Ho, Victor W., Tang, Kwan Ho, Paterson, Joshua, Clarke, Blaise A., Bernardini, Marcus Q., Bader, Gary D., Neel, Benjamin G., Ailles, Laurie E.
Publicado 2020

Synaptic restoration by cAMP/PKA drives activity-dependent neuroprotection to motoneurons in ALS

por Bączyk, Marcin, Alami, Najwa Ouali, Delestrée, Nicolas, Martinot, Clémence, Tang, Linyun, Commisso, Barbara, Bayer, David, Doisne, Nicolas, Frankel, Wayne, Manuel, Marin, Roselli, Francesco, Zytnicki, Daniel
Publicado 2020

cDC1 dysregulation in cancer: An opportunity for intervention

por Gajewski, Thomas F., Cron, Kyle R.
Publicado 2020

Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling

por Israelow, Benjamin, Song, Eric, Mao, Tianyang, Lu, Peiwen, Meir, Amit, Liu, Feimei, Alfajaro, Mia Madel, Wei, Jin, Dong, Huiping, Homer, Robert J., Ring, Aaron, Wilen, Craig B., Iwasaki, Akiko
Publicado 2020

Protrudin-mediated ER–endosome contact sites promote MT1-MMP exocytosis and cell invasion

por Pedersen, Nina Marie, Wenzel, Eva Maria, Wang, Ling, Antoine, Sandra, Chavrier, Philippe, Stenmark, Harald, Raiborg, Camilla
Publicado 2020

SARM1 acts downstream of neuroinflammatory and necroptotic signaling to induce axon degeneration

por Ko, Kwang Woo, Milbrandt, Jeffrey, DiAntonio, Aaron
Publicado 2020

TANGLED1 mediates microtubule interactions that may promote division plane positioning in maize

por Martinez, Pablo, Dixit, Ram, Balkunde, Rachappa S., Zhang, Antonia, O’Leary, Seán E., Brakke, Kenneth A., Rasmussen, Carolyn G.
Publicado 2020

Topological features of integrin adhesion complexes revealed by multiplexed proximity biotinylation

por Chastney, Megan R., Lawless, Craig, Humphries, Jonathan D., Warwood, Stacey, Jones, Matthew C., Knight, David, Jorgensen, Claus, Humphries, Martin J.
Publicado 2020

Interferon-stimulated gene 15 accelerates replication fork progression inducing chromosomal breakage

por Raso, Maria Chiara, Djoric, Nikola, Walser, Franziska, Hess, Sandra, Schmid, Fabian Marc, Burger, Sibylle, Knobeloch, Klaus-Peter, Penengo, Lorenza
Publicado 2020

CDK4/6 regulate lysosome biogenesis through TFEB/TFE3

por Yin, Qiuyuan, Jian, Youli, Xu, Meng, Huang, Xiahe, Wang, Niya, Liu, Zhifang, Li, Qian, Li, Jinglin, Zhou, Hejiang, Xu, Lin, Wang, Yingchun, Yang, Chonglin
Publicado 2020

Phospholipid ebb and flow makes mitochondria go

por Acoba, Michelle Grace, Senoo, Nanami, Claypool, Steven M.
Publicado 2020

Individual kinetochore-fibers locally dissipate force to maintain robust mammalian spindle structure

por Long, Alexandra F., Suresh, Pooja, Dumont, Sophie
Publicado 2020

HDAC6 regulates microtubule stability and clustering of AChRs at neuromuscular junctions

por Osseni, Alexis, Ravel-Chapuis, Aymeric, Thomas, Jean-Luc, Gache, Vincent, Schaeffer, Laurent, Jasmin, Bernard J.
Publicado 2020

Tissue specific requirement of Drosophila Rcd4 for centriole duplication and ciliogenesis

por Panda, Pallavi, Kovacs, Levente, Dzhindzhev, Nikola, Fatalska, Agnieszka, Persico, Veronica, Geymonat, Marco, Riparbelli, Maria Giovanna, Callaini, Giuliano, Glover, David M.
Publicado 2020