Poor quality Vβ recombination signal sequences stochastically enforce TCRβ allelic exclusion

por Wu, Glendon S., Yang-Iott, Katherine S., Klink, Morgann A., Hayer, Katharina E., Lee, Kyutae D., Bassing, Craig H.
Publicado 2020

Blueprint of human thymopoiesis reveals molecular mechanisms of stage-specific TCR enhancer activation

por Cieslak, Agata, Charbonnier, Guillaume, Tesio, Melania, Mathieu, Eve-Lyne, Belhocine, Mohamed, Touzart, Aurore, Smith, Charlotte, Hypolite, Guillaume, Andrieu, Guillaume P., Martens, Joost H.A., Janssen-Megens, Eva, Gut, Marta, Gut, Ivo, Boissel, Nicolas, Petit, Arnaud, Puthier, Denis, Macintyre, Elizabeth, Stunnenberg, Hendrik G., Spicuglia, Salvatore, Asnafi, Vahid
Publicado 2020

Japanese encephalitis virus–primed CD8(+) T cells prevent antibody-dependent enhancement of Zika virus pathogenesis

por Chen, Dong, Duan, Zhiliang, Zhou, Wenhua, Zou, Weiwei, Jin, Shengwei, Li, Dezhou, Chen, Xinyu, Zhou, Yongchao, Yang, Lan, Zhang, Yanjun, Shresta, Sujan, Wen, Jinsheng
Publicado 2020

Targeting leukocidin-mediated immune evasion protects mice from Staphylococcus aureus bacteremia

por Tam, Kayan, Lacey, Keenan A., Devlin, Joseph C., Coffre, Maryaline, Sommerfield, Alexis, Chan, Rita, O’Malley, Aidan, Koralov, Sergei B., Loke, P’ng, Torres, Victor J.
Publicado 2020

Layilin augments integrin activation to promote antitumor immunity

por Mahuron, Kelly M., Moreau, Joshua M., Glasgow, Jeff E., Boda, Devi P., Pauli, Mariela L., Gouirand, Victoire, Panjabi, Luv, Grewal, Robby, Luber, Jacob M., Mathur, Anubhav N., Feldman, Renny M., Shifrut, Eric, Mehta, Pooja, Lowe, Margaret M., Alvarado, Michael D., Marson, Alexander, Singer, Meromit, Wells, Jim, Jupp, Ray, Daud, Adil I., Rosenblum, Michael D.
Publicado 2020

RSSs set the odds for exclusion

por Krangel, Michael S.
Publicado 2020

Correction: Ablation of endothelial VEGFR1 improves metabolic dysfunction by inducing adipose tissue browning

por Seki, Takahiro, Hosaka, Kayoko, Fischer, Carina, Lim, Sharon, Andersson, Patrik, Abe, Mitsuhiko, Iwamoto, Hideki, Gao, Yanyan, Wang, Xinsheng, Fong, Guo-Hua, Cao, Yihai
Publicado 2020

Cbl and Cbl-b control the germinal center reaction by facilitating naive B cell antigen processing

por Li, Xin, Gong, Liying, Meli, Alexandre P., Karo-Atar, Danielle, Sun, Weili, Zou, Yongrui, King, Irah L., Gu, Hua
Publicado 2020

Distinct functions of tissue-resident and circulating memory Th2 cells in allergic airway disease

por Rahimi, Rod A., Nepal, Keshav, Cetinbas, Murat, Sadreyev, Ruslan I., Luster, Andrew D.
Publicado 2020

Anti-human TREM2 induces microglia proliferation and reduces pathology in an Alzheimer’s disease model

por Wang, Shoutang, Mustafa, Meer, Yuede, Carla M., Salazar, Santiago Viveros, Kong, Philip, Long, Hua, Ward, Michael, Siddiqui, Omer, Paul, Robert, Gilfillan, Susan, Ibrahim, Adiljan, Rhinn, Hervé, Tassi, Ilaria, Rosenthal, Arnon, Schwabe, Tina, Colonna, Marco
Publicado 2020

BACH2 drives quiescence and maintenance of resting Treg cells to promote homeostasis and cancer immunosuppression

por Grant, Francis M., Yang, Jie, Nasrallah, Rabab, Clarke, James, Sadiyah, Firas, Whiteside, Sarah K., Imianowski, Charlotte J., Kuo, Paula, Vardaka, Panagiota, Todorov, Tihomir, Zandhuis, Nordin, Patrascan, Ilinca, Tough, David F., Kometani, Kohei, Eil, Robert, Kurosaki, Tomohiro, Okkenhaug, Klaus, Roychoudhuri, Rahul
Publicado 2020

Longevity and replenishment of human liver-resident memory T cells and mononuclear phagocytes

por Pallett, Laura J., Burton, Alice R., Amin, Oliver E., Rodriguez-Tajes, Sergio, Patel, Amit A., Zakeri, Nekisa, Jeffery-Smith, Anna, Swadling, Leo, Schmidt, Nathalie M., Baiges, Anna, Gander, Amir, Yu, Dominic, Nasralla, David, Froghi, Farid, Iype, Satheesh, Davidson, Brian R., Thorburn, Douglas, Yona, Simon, Forns, Xavier, Maini, Mala K.
Publicado 2020

Relative contribution of nonstructural protein 1 in dengue pathogenesis

por Lee, Pei Xuan, Ting, Donald Heng Rong, Boey, Clement Peng Hee, Tan, Eunice Tze Xin, Chia, Janice Zuo Hui, Idris, Fakhriedzwan, Oo, Yukei, Ong, Li Ching, Chua, Yen Leong, Hapuarachchi, Chanditha, Ng, Lee Ching, Alonso, Sylvie
Publicado 2020

Membrane budding is a major mechanism of in vivo platelet biogenesis

por Potts, Kathryn S., Farley, Alison, Dawson, Caleb A., Rimes, Joel, Biben, Christine, de Graaf, Carolyn, Potts, Margaret A., Stonehouse, Olivia J., Carmagnac, Amandine, Gangatirkar, Pradnya, Josefsson, Emma C., Anttila, Casey, Amann-Zalcenstein, Daniela, Naik, Shalin, Alexander, Warren S., Hilton, Douglas J., Hawkins, Edwin D., Taoudi, Samir
Publicado 2020

Neuronal interleukin-1 receptors mediate pain in chronic inflammatory diseases

por Mailhot, Benoit, Christin, Marine, Tessandier, Nicolas, Sotoudeh, Chaudy, Bretheau, Floriane, Turmel, Roxanne, Pellerin, Ève, Wang, Feng, Bories, Cyril, Joly-Beauparlant, Charles, De Koninck, Yves, Droit, Arnaud, Cicchetti, Francesca, Scherrer, Grégory, Boilard, Eric, Sharif-Naeini, Reza, Lacroix, Steve
Publicado 2020

Pancreatic cancer SLUGged

por Josselsohn, Rachel H., Tuveson, David A.
Publicado 2020

Loss of decay-accelerating factor triggers podocyte injury and glomerulosclerosis

por Angeletti, Andrea, Cantarelli, Chiara, Petrosyan, Astgik, Andrighetto, Sofia, Budge, Kelly, D’Agati, Vivette D., Hartzell, Susan, Malvi, Deborah, Donadei, Chiara, Thurman, Joshua M., Galešić-Ljubanović, Danica, He, John Cijiang, Xiao, Wenzhen, Campbell, Kirk N., Wong, Jenny, Fischman, Clara, Manrique, Joaquin, Zaza, Gianluigi, Fiaccadori, Enrico, La Manna, Gaetano, Fribourg, Miguel, Leventhal, Jeremy, Da Sacco, Stefano, Perin, Laura, Heeger, Peter S., Cravedi, Paolo
Publicado 2020

Autologous tumor cell vaccine induces antitumor T cell immune responses in patients with mantle cell lymphoma: A phase I/II trial

por Frank, Matthew J., Khodadoust, Michael S., Czerwinski, Debra K., Haabeth, Ole A.W., Chu, Michael P., Miklos, David B., Advani, Ranjana H., Alizadeh, Ash A., Gupta, Neel K., Maeda, Lauren S., Reddy, Sunil A., Laport, Ginna G., Meyer, Everett H., Negrin, Robert S., Rezvani, Andrew R., Weng, Wen-Kai, Sheehan, Kevin, Faham, Malek, Okada, Ami, Moore, A. Holliston, Phillips, Destiny L., Wapnir, Irene L., Brody, Joshua D., Levy, Ronald
Publicado 2020

SOAT1 promotes mevalonate pathway dependency in pancreatic cancer

por Oni, Tobiloba E., Biffi, Giulia, Baker, Lindsey A., Hao, Yuan, Tonelli, Claudia, Somerville, Tim D.D., Deschênes, Astrid, Belleau, Pascal, Hwang, Chang-il, Sánchez-Rivera, Francisco J., Cox, Hilary, Brosnan, Erin, Doshi, Abhishek, Lumia, Rebecca P., Khaledi, Kimia, Park, Youngkyu, Trotman, Lloyd C., Lowe, Scott W., Krasnitz, Alexander, Vakoc, Christopher R., Tuveson, David A.
Publicado 2020

IL-33 promotes anemia during chronic inflammation by inhibiting differentiation of erythroid progenitors

por Swann, James W., Koneva, Lada A., Regan-Komito, Daniel, Sansom, Stephen N., Powrie, Fiona, Griseri, Thibault
Publicado 2020