Neutralizing hepatitis B

por Robbiani, Davide F.
Publicado 2020

Cancer cell CCR2 orchestrates suppression of the adaptive immune response

por Fein, Miriam R., He, Xue-Yan, Almeida, Ana S., Bružas, Emilis, Pommier, Arnaud, Yan, Ran, Eberhardt, Anaïs, Fearon, Douglas T., Van Aelst, Linda, Wilkinson, John Erby, dos Santos, Camila O., Egeblad, Mikala
Publicado 2020

Ganglioneuromas are driven by activated AKT and can be therapeutically targeted with mTOR inhibitors

por Tao, Ting, Shi, Hui, Wang, Meng, Perez-Atayde, Antonio R., London, Wendy B., Gutierrez, Alejandro, Lemos, Bernardo, Durbin, Adam D., Look, A. Thomas
Publicado 2020

Noncanonical STAT3 activity sustains pathogenic Th17 proliferation and cytokine response to antigen

por Poholek, Catherine H., Raphael, Itay, Wu, Dongwen, Revu, Shankar, Rittenhouse, Natalie, Uche, Uzodinma U., Majumder, Saikat, Kane, Lawrence P., Poholek, Amanda C., McGeachy, Mandy J.
Publicado 2020

Transmembrane TNF drives osteoproliferative joint inflammation reminiscent of human spondyloarthritis

por Kaaij, Merlijn H., van Tok, Melissa N., Blijdorp, Iris C., Ambarus, Carmen A., Stock, Michael, Pots, Désiree, Knaup, Véronique L., Armaka, Marietta, Christodoulou-Vafeiadou, Eleni, van Melsen, Tessa K., Masdar, Huriatul, Eskes, Harry J.P.P., Yeremenko, Nataliya G., Kollias, George, Schett, Georg, Tas, Sander W., van Duivenvoorde, Leonie M., Baeten, Dominique L.P.
Publicado 2020

Potent human broadly neutralizing antibodies to hepatitis B virus from natural controllers

por Hehle, Verena, Beretta, Maxime, Bourgine, Maryline, Ait-Goughoulte, Malika, Planchais, Cyril, Morisse, Solen, Vesin, Benjamin, Lorin, Valérie, Hieu, Thierry, Stauffer, Andrea, Fiquet, Oriane, Dimitrov, Jordan D., Michel, Marie-Louise, Ungeheuer, Marie-Noëlle, Sureau, Camille, Pol, Stanislas, Di Santo, James P., Strick-Marchand, Hélène, Pelletier, Nadège, Mouquet, Hugo
Publicado 2020

The NLRP3–inflammasome as a sensor of organelle dysfunction

por Seoane, Paula I., Lee, Bali, Hoyle, Christopher, Yu, Shi, Lopez-Castejon, Gloria, Lowe, Martin, Brough, David
Publicado 2020

PD-1 restraint of regulatory T cell suppressive activity is critical for immune tolerance

por Tan, Catherine L., Kuchroo, Juhi R., Sage, Peter T., Liang, Dan, Francisco, Loise M., Buck, Jessica, Thaker, Youg Raj, Zhang, Qianxia, McArdel, Shannon L., Juneja, Vikram R., Lee, Sun Jung, Lovitch, Scott B., Lian, Christine, Murphy, George F., Blazar, Bruce R., Vignali, Dario A.A., Freeman, Gordon J., Sharpe, Arlene H.
Publicado 2020

Qki is an essential regulator of microglial phagocytosis in demyelination

por Ren, Jiangong, Dai, Congxin, Zhou, Xin, Barnes, Joseph A., Chen, Xi, Wang, Yunfei, Yuan, Liang, Shingu, Takashi, Heimberger, Amy B., Chen, Yiwen, Hu, Jian
Publicado 2020

The EB1–Kinesin-14 complex is required for efficient metaphase spindle assembly and kinetochore bi-orientation

por Kornakov, Nikolay, Möllers, Bastian, Westermann, Stefan
Publicado 2020

Spatial regulation of clathrin-mediated endocytosis through position-dependent site maturation

por Pedersen, Ross T.A., Hassinger, Julian E., Marchando, Paul, Drubin, David G.
Publicado 2020

MICOS subcomplexes assemble independently on the mitochondrial inner membrane in proximity to ER contact sites

por Tirrell, Parker S., Nguyen, Kailey N., Luby-Phelps, Katherine, Friedman, Jonathan R.
Publicado 2020

4-1BB (CD137) in anticancer chimeras

por Melero, Ignacio, Berraondo, Pedro
Publicado 2020

Cell division requires RNA eviction from condensing chromosomes

por Sharp, Judith A., Perea-Resa, Carlos, Wang, Wei, Blower, Michael D.
Publicado 2020

SHP2 inhibition diminishes KRAS(G12C) cycling and promotes tumor microenvironment remodeling

por Fedele, Carmine, Li, Shuai, Teng, Kai Wen, Foster, Connor J.R., Peng, David, Ran, Hao, Mita, Paolo, Geer, Mitchell J., Hattori, Takamitsu, Koide, Akiko, Wang, Yubao, Tang, Kwan Ho, Leinwand, Joshua, Wang, Wei, Diskin, Brian, Deng, Jiehui, Chen, Ting, Dolgalev, Igor, Ozerdem, Ugur, Miller, George, Koide, Shohei, Wong, Kwok-Kin, Neel, Benjamin G.
Publicado 2020

ECM deposition is driven by caveolin-1–dependent regulation of exosomal biogenesis and cargo sorting

por Albacete-Albacete, Lucas, Navarro-Lérida, Inmaculada, López, Juan Antonio, Martín-Padura, Inés, Astudillo, Alma M., Ferrarini, Alessia, Van-Der-Heyden, Michael, Balsinde, Jesús, Orend, Gertraud, Vázquez, Jesús, del Pozo, Miguel Ángel
Publicado 2020

Molecular imaging of Alzheimer’s disease–related gamma-secretase in mice and nonhuman primates

por Xu, Yulong, Wang, Changning, Wey, Hsiao-Ying, Liang, Yingxia, Chen, Zude, Choi, Se Hoon, Ran, Chongzhao, Rynearson, Kevin D., Bernales, Daniela R., Koegel, Robert E., Fiedler, Stephanie A., Striar, Robin, Wagner, Steven L., Tanzi, Rudolph E., Zhang, Can
Publicado 2020

The mitotic protein NuMA plays a spindle-independent role in nuclear formation and mechanics

por Serra-Marques, Andrea, Houtekamer, Ronja, Hintzen, Dorine, Canty, John T., Yildiz, Ahmet, Dumont, Sophie
Publicado 2020

Lysine acetylation of cytoskeletal proteins: Emergence of an actin code

por A, Mu, Latario, Casey J., Pickrell, Laura E., Higgs, Henry N.
Publicado 2020

Exit from germinal center to become quiescent memory B cells depends on metabolic reprograming and provision of a survival signal

por Inoue, Takeshi, Shinnakasu, Ryo, Kawai, Chie, Ise, Wataru, Kawakami, Eiryo, Sax, Nicolas, Oki, Toshihiko, Kitamura, Toshio, Yamashita, Kazuo, Fukuyama, Hidehiro, Kurosaki, Tomohiro
Publicado 2020