Sustained androgen receptor signaling is a determinant of melanoma cell growth potential and tumorigenesis

por Ma, Min, Ghosh, Soumitra, Tavernari, Daniele, Katarkar, Atul, Clocchiatti, Andrea, Mazzeo, Luigi, Samarkina, Anastasia, Epiney, Justine, Yu, Yi-Ru, Ho, Ping-Chih, Levesque, Mitchell P., Özdemir, Berna C., Ciriello, Giovanni, Dummer, Reinhard, Dotto, G. Paolo
Publicado 2020

Critical requirement for BCR, BAFF, and BAFFR in memory B cell survival

por Müller-Winkler, Jennifer, Mitter, Richard, Rappe, Julie C.F., Vanes, Lesley, Schweighoffer, Edina, Mohammadi, Hamid, Wack, Andreas, Tybulewicz, Victor L.J.
Publicado 2020

BAFFR controls early memory B cell responses but is dispensable for germinal center function

por Lau, Angelica W.Y., Turner, Vivian M., Bourne, Katherine, Hermes, Jana R., Chan, Tyani D., Brink, Robert
Publicado 2020

PPM1F controls integrin activity via a conserved phospho-switch

por Grimm, Tanja M., Dierdorf, Nina I., Betz, Karin, Paone, Christoph, Hauck, Christof R.
Publicado 2020

Kinetochore phosphatases suppress autonomous Polo-like kinase 1 activity to control the mitotic checkpoint

por Cordeiro, Marilia H., Smith, Richard J., Saurin, Adrian T.
Publicado 2020

Type I interferon signaling mediates Mycobacterium tuberculosis–induced macrophage death

por Zhang, Li, Jiang, Xiuju, Pfau, Daniel, Ling, Yan, Nathan, Carl F.
Publicado 2020

miR-155 promotes T reg cell development by safeguarding medullary thymic epithelial cell maturation

por Dong, Jiayi, Warner, Lindsey M., Lin, Ling-Li, Chen, Mei-Chi, O'Connell, Ryan M., Lu, Li-Fan
Publicado 2020

Genome-wide mutational signatures revealed distinct developmental paths for human B cell lymphomas

por Ye, Xiaofei, Ren, Weicheng, Liu, Dongbing, Li, Xiaobo, Li, Wei, Wang, Xianhuo, Meng, Fei-Long, Yeap, Leng-Siew, Hou, Yong, Zhu, Shida, Casellas, Rafael, Zhang, Huilai, Wu, Kui, Pan-Hammarström, Qiang
Publicado 2020

The T cell CD6 receptor operates a multitask signalosome with opposite functions in T cell activation

por Mori, Daiki, Grégoire, Claude, Voisinne, Guillaume, Celis-Gutierrez, Javier, Aussel, Rudy, Girard, Laura, Camus, Mylène, Marcellin, Marlène, Argenty, Jérémy, Burlet-Schiltz, Odile, Fiore, Frédéric, Gonzalez de Peredo, Anne, Malissen, Marie, Roncagalli, Romain, Malissen, Bernard
Publicado 2020

A cryo-ET survey of microtubules and intracellular compartments in mammalian axons

por Foster, Helen E., Ventura Santos, Camilla, Carter, Andrew P.
Publicado 2021

αv-Class integrin binding to fibronectin is solely mediated by RGD and unaffected by an RGE mutation

por Benito-Jardón, María, Strohmeyer, Nico, Ortega-Sanchís, Sheila, Bharadwaj, Mitasha, Moser, Markus, Müller, Daniel J., Fässler, Reinhard, Costell, Mercedes
Publicado 2020

Hepatic stellate and endothelial cells maintain hematopoietic stem cells in the developing liver

por Lee, Yeojin, Leslie, Juliana, Yang, Ying, Ding, Lei
Publicado 2020

The mRNA m(6)A reader YTHDF2 suppresses proinflammatory pathways and sustains hematopoietic stem cell function

por Mapperley, Christopher, van de Lagemaat, Louie N., Lawson, Hannah, Tavosanis, Andrea, Paris, Jasmin, Campos, Joana, Wotherspoon, David, Durko, Jozef, Sarapuu, Annika, Choe, Junho, Ivanova, Ivayla, Krause, Daniela S., von Kriegsheim, Alex, Much, Christian, Morgan, Marcos, Gregory, Richard I., Mead, Adam J., O’Carroll, Dónal, Kranc, Kamil R.
Publicado 2020

Optimized gene engineering of murine CAR-T cells reveals the beneficial effects of IL-15 coexpression

por Lanitis, Evripidis, Rota, Giorgia, Kosti, Paris, Ronet, Catherine, Spill, Aodrenn, Seijo, Bili, Romero, Pedro, Dangaj, Denarda, Coukos, George, Irving, Melita
Publicado 2020

The ER cholesterol sensor SCAP promotes CARTS biogenesis at ER–Golgi membrane contact sites

por Wakana, Yuichi, Hayashi, Kaito, Nemoto, Takumi, Watanabe, Chiaki, Taoka, Masato, Angulo-Capel, Jessica, Garcia-Parajo, Maria F., Kumata, Hidetoshi, Umemura, Tomonari, Inoue, Hiroki, Arasaki, Kohei, Campelo, Felix, Tagaya, Mitsuo
Publicado 2020

A distinct CD38(+)CD45RA(+) population of CD4(+), CD8(+), and double-negative T cells is controlled by FAS

por Maccari, Maria Elena, Fuchs, Sebastian, Kury, Patrick, Andrieux, Geoffroy, Völkl, Simon, Bengsch, Bertram, Lorenz, Myriam Ricarda, Heeg, Maximilian, Rohr, Jan, Jägle, Sabine, Castro, Carla N., Groß, Miriam, Warthorst, Ursula, König, Christoph, Fuchs, Ilka, Speckmann, Carsten, Thalhammer, Julian, Kapp, Friedrich G., Seidel, Markus G., Dückers, Gregor, Schönberger, Stefan, Schütz, Catharina, Führer, Marita, Kobbe, Robin, Holzinger, Dirk, Klemann, Christian, Smisek, Petr, Owens, Stephen, Horneff, Gerd, Kolb, Reinhard, Naumann-Bartsch, Nora, Miano, Maurizio, Staniek, Julian, Rizzi, Marta, Kalina, Tomas, Schneider, Pascal, Erxleben, Anika, Backofen, Rolf, Ekici, Arif, Niemeyer, Charlotte M., Warnatz, Klaus, Grimbacher, Bodo, Eibel, Hermann, Mackensen, Andreas, Frei, Andreas Philipp, Schwarz, Klaus, Boerries, Melanie, Ehl, Stephan, Rensing-Ehl, Anne
Publicado 2020

Centriole-independent mitotic spindle assembly relies on the PCNT–CDK5RAP2 pericentriolar matrix

por Watanabe, Sadanori, Meitinger, Franz, Shiau, Andrew K., Oegema, Karen, Desai, Arshad
Publicado 2020

Genetically encoded live-cell sensor for tyrosinated microtubules

por Kesarwani, Shubham, Lama, Prakash, Chandra, Anchal, Reddy, P. Purushotam, Jijumon, A.S., Bodakuntla, Satish, Rao, Balaji M., Janke, Carsten, Das, Ranabir, Sirajuddin, Minhajuddin
Publicado 2020

An antibody toolbox to track complex I assembly defines AIF’s mitochondrial function

por Murari, Anjaneyulu, Rhooms, Shauna-Kay, Goparaju, Naga Sri, Villanueva, Maximino, Owusu-Ansah, Edward
Publicado 2020

Wnts regulate planar cell polarity via heterotrimeric G protein and PI3K signaling

por Landin Malt, Andre, Hogan, Arielle K., Smith, Connor D., Madani, Maxwell S., Lu, Xiaowei
Publicado 2020