Plasmodium falciparum–specific IgM B cells dominate in children, expand with malaria, and produce functional IgM

por Hopp, Christine S., Sekar, Padmapriya, Diouf, Ababacar, Miura, Kazutoyo, Boswell, Kristin, Skinner, Jeff, Tipton, Christopher M., Peterson, Mary E., Chambers, Michael J., Andrews, Sarah, Lu, Jinghua, Tan, Joshua, Li, Shanping, Doumbo, Safiatou, Kayentao, Kassoum, Ongoiba, Aissata, Traore, Boubacar, Portugal, Silvia, Sun, Peter D., Long, Carole, Koup, Richard A., Long, Eric O., McDermott, Adrian B., Crompton, Peter D.
Publicado 2021

Group 2 innate lymphoid cells support hematopoietic recovery under stress conditions

por Sudo, Takao, Motomura, Yasutaka, Okuzaki, Daisuke, Hasegawa, Tetsuo, Yokota, Takafumi, Kikuta, Junichi, Ao, Tomoka, Mizuno, Hiroki, Matsui, Takahiro, Motooka, Daisuke, Yoshizawa, Ryosuke, Nagasawa, Takashi, Kanakura, Yuzuru, Moro, Kazuyo, Ishii, Masaru
Publicado 2021

Reduced insulin/IGF1 signaling prevents immune aging via ZIP-10/bZIP–mediated feedforward loop

por Lee, Yujin, Jung, Yoonji, Jeong, Dae-Eun, Hwang, Wooseon, Ham, Seokjin, Park, Hae-Eun H., Kwon, Sujeong, Ashraf, Jasmine M., Murphy, Coleen T., Lee, Seung-Jae V.
Publicado 2021

ALS2 regulates endosomal trafficking, postsynaptic development, and neuronal survival

por Kim, Joohyung, Kim, Sungdae, Nahm, Minyeop, Li, Tsai-Ning, Lin, Hsin-Chieh, Kim, Yeongjin David, Lee, Jihye, Yao, Chi-Kuang, Lee, Seungbok
Publicado 2021

Resin-acid derivatives bind to multiple sites on the voltage-sensor domain of the Shaker potassium channel

por Silverå Ejneby, Malin, Gromova, Arina, Ottosson, Nina E., Borg, Stina, Estrada-Mondragón, Argel, Yazdi, Samira, Apostolakis, Panagiotis, Elinder, Fredrik, Delemotte, Lucie
Publicado 2021

A promising new γ-secretase modulator for Alzheimer’s disease

por Dobrowolska Zakaria, Justyna A., Vassar, Robert J.
Publicado 2021

cMyBPC phosphorylation modulates the effect of omecamtiv mecarbil on myocardial force generation

por Mamidi, Ranganath, Holmes, Joshua B., Doh, Chang Yoon, Dominic, Katherine L., Madugula, Nikhil, Stelzer, Julian E.
Publicado 2021

FXYD proteins and sodium pump regulatory mechanisms

por Yap, John Q., Seflova, Jaroslava, Sweazey, Ryan, Artigas, Pablo, Robia, Seth L.
Publicado 2021

An asymmetric junctional mechanoresponse coordinates mitotic rounding with epithelial integrity

por Monster, Jooske L., Donker, Lisa, Vliem, Marjolein J., Win, Zaw, Matthews, Helen K., Cheah, Joleen S., Yamada, Soichiro, de Rooij, Johan, Baum, Buzz, Gloerich, Martijn
Publicado 2021

Endoplasmic reticulum maintains ion homeostasis required for plasma membrane repair

por Chandra, Goutam, Sreetama, Sen Chandra, Mázala, Davi A.G., Charton, Karine, VanderMeulen, Jack H., Richard, Isabelle, Jaiswal, Jyoti K.
Publicado 2021

FUS-dependent liquid–liquid phase separation is important for DNA repair initiation

por Levone, Brunno R., Lenzken, Silvia C., Antonaci, Marco, Maiser, Andreas, Rapp, Alexander, Conte, Francesca, Reber, Stefan, Mechtersheimer, Jonas, Ronchi, Antonella E., Mühlemann, Oliver, Leonhardt, Heinrich, Cardoso, M. Cristina, Ruepp, Marc-David, Barabino, Silvia M.L.
Publicado 2021

Targeting mechanosensitive MDM4 promotes lung fibrosis resolution in aged mice

por Qu, Jing, Yang, Shan-Zhong, Zhu, Yi, Guo, Ting, Thannickal, Victor J., Zhou, Yong
Publicado 2021

Hepatic Gadd45β promotes hyperglycemia and glucose intolerance through DNA demethylation of PGC-1α

por Wu, Ling, Jiao, Yang, Li, Yao, Jiang, Jingjing, Zhao, Lin, Li, Menghui, Li, Bin, Yan, Zheng, Chen, Xuejin, Li, Xiaoying, Lu, Yan
Publicado 2021

30 years of observations and hopes for faster progress on promoting the status of women in science

por Randolph, Gwendalyn J.
Publicado 2021

Anastacia Awad: Women in STEM outside the lab

por Houston, Stephanie
Publicado 2021

Correction: Human IgA bind a diverse array of commensal bacteria

por Sterlin, Delphine, Fadlallah, Jehane, Adams, Olivia, Fieschi, Claire, Parizot, Christophe, Dorgham, Karim, Rajkumar, Asok, Autaa, Gaëlle, El-Kafsi, Hela, Charuel, Jean-Luc, Juste, Catherine, Jönsson, Friederike, Candela, Thomas, Wardemann, Hedda, Aubry, Alexandra, Capito, Carmen, Brisson, Hélène, Tresallet, Christophe, Cummings, Richard D., Larsen, Martin, Yssel, Hans, von Gunten, Stephan, Gorochov, Guy
Publicado 2020

Structural basis of cytoplasmic Na(V)1.5 and Na(V)1.4 regulation

por Nathan, Sara, Gabelli, Sandra B., Yoder, Jesse B., Srinivasan, Lakshmi, Aldrich, Richard W., Tomaselli, Gordon F., Ben-Johny, Manu, Amzel, L. Mario
Publicado 2020

A crucial role for Jagunal homolog 1 in humoral immunity and antibody glycosylation in mice and humans

por Hagelkruys, Astrid, Wirnsberger, Gerald, Stadlmann, Johannes, Wöhner, Miriam, Horrer, Marion, Vilagos, Bojan, Jonsson, Gustav, Kogler, Melanie, Tortola, Luigi, Novatchkova, Maria, Bönelt, Peter, Hoffmann, David, Koglgruber, Rubina, Steffen, Ulrike, Schett, Georg, Busslinger, Meinrad, Bergthaler, Andreas, Klein, Christoph, Penninger, Josef M.
Publicado 2020

Spatiotemporal restriction of endothelial cell calcium signaling is required during leukocyte transmigration

por Dalal, Prarthana J., Sullivan, David P., Weber, Evan W., Sacks, David B., Gunzer, Matthias, Grumbach, Isabella M., Heller Brown, Joan, Muller, William A.
Publicado 2020

Lack of NFATc1 SUMOylation prevents autoimmunity and alloreactivity

por Xiao, Yin, Qureischi, Musga, Dietz, Lena, Vaeth, Martin, Vallabhapurapu, Subrahmanya D., Klein-Hessling, Stefan, Klein, Matthias, Liang, Chunguang, König, Anika, Serfling, Edgar, Mottok, Anja, Bopp, Tobias, Rosenwald, Andreas, Buttmann, Mathias, Berberich, Ingolf, Beilhack, Andreas, Berberich-Siebelt, Friederike
Publicado 2020