PMN-derived netrin-1 attenuates cardiac ischemia-reperfusion injury via myeloid ADORA2B signaling

por Li, Jiwen, Conrad, Catharina, Mills, Tingting W., Berg, Nathaniel K., Kim, Boyun, Ruan, Wei, Lee, Jae W., Zhang, Xu, Yuan, Xiaoyi, Eltzschig, Holger K.
Publicado 2021

STARTRAC analyses of scRNAseq data from tumor models reveal T cell dynamics and therapeutic targets

por Bhatt, Dev, Kang, Boxi, Sawant, Deepali, Zheng, Liangtao, Perez, Kristy, Huang, Zhiyu, Sekirov, Laura, Wolak, Dan, Huang, Julie Y., Liu, Xian, DeVoss, Jason, Manzanillo, Paolo S., Pierce, Nathan, Zhang, Zemin, Symons, Antony, Ouyang, Wenjun
Publicado 2021

TMEM41B and VMP1 are scramblases and regulate the distribution of cholesterol and phosphatidylserine

por Li, Yang Emma, Wang, Yichang, Du, Ximing, Zhang, Tizhong, Mak, Hoi Yin, Hancock, Sarah E., McEwen, Holly, Pandzic, Elvis, Whan, Renee M., Aw, Yvette Celine, Lukmantara, Ivan E., Yuan, Yiqiong, Dong, Xiuju, Don, Anthony, Turner, Nigel, Qi, Shiqian, Yang, Hongyuan
Publicado 2021

VPS13D bridges the ER to mitochondria and peroxisomes via Miro

por Guillén-Samander, Andrés, Leonzino, Marianna, Hanna, Michael G., Tang, Ni, Shen, Hongying, De Camilli, Pietro
Publicado 2021

VPS13D promotes peroxisome biogenesis

por Baldwin, Heather A., Wang, Chunxin, Kanfer, Gil, Shah, Hetal V., Velayos-Baeza, Antonio, Dulovic-Mahlow, Marija, Brüggemann, Norbert, Anding, Allyson, Baehrecke, Eric H., Maric, Dragan, Prinz, William A., Youle, Richard J.
Publicado 2021

SARS-CoV-2–related MIS-C: A key to the viral and genetic causes of Kawasaki disease?

por Sancho-Shimizu, Vanessa, Brodin, Petter, Cobat, Aurélie, Biggs, Catherine M., Toubiana, Julie, Lucas, Carrie L., Henrickson, Sarah E., Belot, Alexandre, Tangye, Stuart G., Milner, Joshua D., Levin, Michael, Abel, Laurent, Bogunovic, Dusan, Casanova, Jean-Laurent, Zhang, Shen-Ying
Publicado 2021

Ubiquitous membrane-bound DNase activity in podosomes and invadopodia

por Pal, Kaushik, Zhao, Yuanchang, Wang, Yongliang, Wang, Xuefeng
Publicado 2021

Tension promotes kinetochore–microtubule release by Aurora B kinase

por Chen, Geng-Yuan, Renda, Fioranna, Zhang, Huaiying, Gokden, Alper, Wu, Daniel Z., Chenoweth, David M., Khodjakov, Alexey, Lampson, Michael A.
Publicado 2021

Immunogenicity and efficacy of one and two doses of Ad26.COV2.S COVID vaccine in adult and aged NHP

por Solforosi, Laura, Kuipers, Harmjan, Jongeneelen, Mandy, Rosendahl Huber, Sietske K., van der Lubbe, Joan E.M., Dekking, Liesbeth, Czapska-Casey, Dominika N., Izquierdo Gil, Ana, Baert, Miranda R.M., Drijver, Joke, Vaneman, Joost, van Huizen, Ella, Choi, Ying, Vreugdenhil, Jessica, Kroos, Sanne, de Wilde, Adriaan H., Kourkouta, Eleni, Custers, Jerome, van der Vlugt, Remko, Veldman, Daniel, Huizingh, Jeroen, Kaszas, Krisztian, Dalebout, Tim J., Myeni, Sebenzile K., Kikkert, Marjolein, Snijder, Eric J., Barouch, Dan H., Böszörményi, Kinga P., Stammes, Marieke A., Kondova, Ivanela, Verschoor, Ernst J., Verstrepen, Babs E., Koopman, Gerrit, Mooij, Petra, Bogers, Willy M.J.M., van Heerden, Marjolein, Muchene, Leacky, Tolboom, Jeroen T.B.M., Roozendaal, Ramon, Brandenburg, Boerries, Schuitemaker, Hanneke, Wegmann, Frank, Zahn, Roland C.
Publicado 2021

Mechanism of mutant calreticulin-mediated activation of the thrombopoietin receptor in cancers

por Venkatesan, Arunkumar, Geng, Jie, Kandarpa, Malathi, Wijeyesakere, Sanjeeva Joseph, Bhide, Ashwini, Talpaz, Moshe, Pogozheva, Irina D., Raghavan, Malini
Publicado 2021

O-GlcNAc modification of nuclear pore complexes accelerates bidirectional transport

por Yoo, Tae Yeon, Mitchison, Timothy J.
Publicado 2021

BFAR coordinates TGFβ signaling to modulate Th9-mediated cancer immunotherapy

por Pei, Siyu, Huang, Mingzhu, Huang, Jia, Zhu, Xiaodong, Wang, Hui, Romano, Simona, Deng, Xiuyu, Wang, Yan, Luo, Yixiao, Hao, Shumeng, Xu, Jing, Yu, Tao, Zhu, Qingchen, Yuan, Jia, Shen, Kunwei, Liu, Zhiqiang, Hu, Guohong, Peng, Chao, Luo, Qingquan, Wen, Zhenzhen, Dai, Dongfang, Xiao, Yichuan
Publicado 2021

Rac1-PAK1 regulation of Rab11 cycling promotes junction destabilization

por Erasmus, Jennifer C., Smolarczyk, Kasia, Brezovjakova, Helena, Mohd-Naim, Noor F., Lozano, Encarnación, Matter, Karl, Braga, Vania M.M.
Publicado 2021

Caspase inhibition prolongs inflammation by promoting a signaling complex with activated RIPK1

por Huang, Xinyue, Tan, Shuixia, Li, Yanxia, Cao, Shuangyi, Li, Xingyan, Pan, Heling, Shan, Bing, Qian, Lihui, Yuan, Junying
Publicado 2021

Ptpn2 and KLRG1 regulate the generation and function of tissue-resident memory CD8(+) T cells in skin

por Hochheiser, Katharina, Wiede, Florian, Wagner, Teagan, Freestone, David, Enders, Matthias H., Olshansky, Moshe, Russ, Brendan, Nüssing, Simone, Bawden, Emma, Braun, Asolina, Bachem, Annabell, Gressier, Elise, McConville, Robyn, Park, Simone L., Jones, Claerwen M., Davey, Gayle M., Gyorki, David E., Tscharke, David, Parish, Ian A., Turner, Stephen, Herold, Marco J., Tiganis, Tony, Bedoui, Sammy, Gebhardt, Thomas
Publicado 2021

Altered selection on a single self-ligand promotes susceptibility to organ-specific T cell infiltration

por Klawon, David E.J., Gilmore, Dana C., Leonard, John D., Miller, Christine H., Chao, Jaime L., Walker, Matthew T., Duncombe, Ryan K., Tung, Kenneth S., Adams, Erin J., Savage, Peter A.
Publicado 2021

Correction: Thermal modulation of epicardial Ca(2+) dynamics uncovers molecular mechanisms of Ca(2+) alternans

por Millet, Jose, Aguilar-Sanchez, Yuriana, Kornyeyev, Dmytro, Bazmi, Maedeh, Fainstein, Diego, Copello, Julio A., Escobar, Ariel L.
Publicado 2021

Planar cell polarity induces local microtubule bundling for coordinated ciliary beating

por Nakayama, Shogo, Yano, Tomoki, Namba, Toshinori, Konishi, Satoshi, Takagishi, Maki, Herawati, Elisa, Nishida, Tomoki, Imoto, Yasuo, Ishihara, Shuji, Takahashi, Masahide, Furuta, Ken’ya, Oiwa, Kazuhiro, Tamura, Atsushi, Tsukita, Sachiko
Publicado 2021

SUMOylation stabilizes sister kinetochore biorientation to allow timely anaphase

por Su, Xue Bessie, Wang, Menglu, Schaffner, Claudia, Nerusheva, Olga O., Clift, Dean, Spanos, Christos, Kelly, David A., Tatham, Michael, Wallek, Andreas, Wu, Yehui, Rappsilber, Juri, Jeyaprakash, A. Arockia, Storchova, Zuzana, Hay, Ronald T., Marston, Adèle L.
Publicado 2021

PLCγ1 promotes phase separation of T cell signaling components

por Zeng, Longhui, Palaia, Ivan, Šarić, Anđela, Su, Xiaolei
Publicado 2021