Caldesmon ablation in mice causes umbilical herniation and alters contractility of fetal urinary bladder smooth muscle

por Pütz, Sandra, Barthel, Lisa Sophie, Frohn, Marina, Metzler, Doris, Barham, Mohammed, Pryymachuk, Galyna, Trunschke, Oliver, Lubomirov, Lubomir T., Hescheler, Jürgen, Chalovich, Joseph M., Neiss, Wolfram F., Koch, Manuel, Schroeter, Mechthild M., Pfitzer, Gabriele
Publicado 2021

A global chromatin compaction pathway that represses germline gene expression during starvation

por Belew, Mezmur D., Chien, Emilie, Wong, Matthew, Michael, W. Matthew
Publicado 2021

Application of fluorescent dextrans to the brain surface under constant pressure reveals AQP4-independent solute uptake

por Smith, Alex J., Akdemir, Gokhan, Wadhwa, Meetu, Song, Dan, Verkman, Alan S.
Publicado 2021

Multi-omic profiling reveals widespread dysregulation of innate immunity and hematopoiesis in COVID-19

por Wilk, Aaron J., Lee, Madeline J., Wei, Bei, Parks, Benjamin, Pi, Ruoxi, Martínez-Colón, Giovanny J., Ranganath, Thanmayi, Zhao, Nancy Q., Taylor, Shalina, Becker, Winston, Jimenez-Morales, David, Blomkalns, Andra L., O’Hara, Ruth, Ashley, Euan A., Nadeau, Kari C., Yang, Samuel, Holmes, Susan, Rabinovitch, Marlene, Rogers, Angela J., Greenleaf, William J., Blish, Catherine A.
Publicado 2021

Dynamic innate immune response determines susceptibility to SARS-CoV-2 infection and early replication kinetics

por Cheemarla, Nagarjuna R., Watkins, Timothy A., Mihaylova, Valia T., Wang, Bao, Zhao, Dejian, Wang, Guilin, Landry, Marie L., Foxman, Ellen F.
Publicado 2021

Innate immune pathways and inflammation in hematopoietic aging, clonal hematopoiesis, and MDS

por Trowbridge, Jennifer J., Starczynowski, Daniel T.
Publicado 2021

Inflammation as a regulator of hematopoietic stem cell function in disease, aging, and clonal selection

por Caiado, Francisco, Pietras, Eric M., Manz, Markus G.
Publicado 2021

Analyzing signaling activity and function in hematopoietic cells

por Kull, Tobias, Schroeder, Timm
Publicado 2021

Inflammatory signaling regulates hematopoietic stem and progenitor cell development and homeostasis

por Collins, Amélie, Mitchell, Carl A., Passegué, Emmanuelle
Publicado 2021

What sugar does to your pores

por Kohler, Jennifer J.
Publicado 2021

Single-cell analysis of the cellular heterogeneity and interactions in the injured mouse spinal cord

por Milich, Lindsay M., Choi, James S., Ryan, Christine, Cerqueira, Susana R., Benavides, Sofia, Yahn, Stephanie L., Tsoulfas, Pantelis, Lee, Jae K.
Publicado 2021

Inhibiting BRD4 to generate BETter T cell memory

por Kasmani, Moujtaba Y., Cui, Weiguo
Publicado 2021

ENaC and ROMK channels in the connecting tubule regulate renal K(+) secretion

por Yang, Lei, Xu, Yuanyuan, Gravotta, Diego, Frindt, Gustavo, Weinstein, Alan M., Palmer, Lawrence G.
Publicado 2021

E3 ligase MKRN3 is a tumor suppressor regulating PABPC1 ubiquitination in non–small cell lung cancer

por Li, Ke, Zheng, Xufen, Tang, Hua, Zang, Yuan-Sheng, Zeng, Chunling, Liu, Xiaoxiao, Shen, Yanying, Pang, Yuzhi, Wang, Simin, Xie, Feifei, Lu, Xiaojing, Luo, Yuxiang, Li, Zhang, Bi, Wenbo, Jia, Xiaona, Huang, Tao, Wei, Rongqiang, Huang, Kenan, Chen, Zihao, Zhu, Qingchen, He, Yi, Zhang, Miaoying, Gu, Zhizhan, Xiao, Yichuan, Zhang, Xiaoyang, Fletcher, Jonathan A., Wang, Yuexiang
Publicado 2021

Human STAT3 variants underlie autosomal dominant hyper-IgE syndrome by negative dominance

por Asano, Takaki, Khourieh, Joëlle, Zhang, Peng, Rapaport, Franck, Spaan, András N., Li, Juan, Lei, Wei-Te, Pelham, Simon J., Hum, David, Chrabieh, Maya, Han, Ji Eun, Guérin, Antoine, Mackie, Joseph, Gupta, Sudhir, Saikia, Biman, Baghdadi, Jamila E.I., Fadil, Ilham, Bousfiha, Aziz, Habib, Tanwir, Marr, Nico, Ganeshanandan, Luckshman, Peake, Jane, Droney, Luke, Williams, Andrew, Celmeli, Fatih, Hatipoglu, Nevin, Ozcelik, Tayfun, Picard, Capucine, Abel, Laurent, Tangye, Stuart G., Boisson-Dupuis, Stéphanie, Zhang, Qian, Puel, Anne, Béziat, Vivien, Casanova, Jean-Laurent, Boisson, Bertrand
Publicado 2021

A Leep1 into migration and macropinocytosis

por Koh, Yvette W.H., Stow, Jennifer L.
Publicado 2021

Tankyrase regulates epithelial lumen formation via suppression of Rab11 GEFs

por Chandrakumar, Arun A., Coyaud, Étienne, Marshall, Christopher B., Ikura, Mitsuhiko, Raught, Brian, Rottapel, Robert
Publicado 2021

Muscle ankyrin repeat protein 1 (MARP1) locks titin to the sarcomeric thin filament and is a passive force regulator

por van der Pijl, Robbert J., van den Berg, Marloes, van de Locht, Martijn, Shen, Shengyi, Bogaards, Sylvia J.P., Conijn, Stefan, Langlais, Paul, Hooijman, Pleuni E., Labeit, Siegfried, Heunks, Leo M.A., Granzier, Henk, Ottenheijm, Coen A.C.
Publicado 2021

GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer’s disease

por Xu, Peng, Chang, Jerry C., Zhou, Xiaopu, Wang, Wei, Bamkole, Michael, Wong, Eitan, Bettayeb, Karima, Jiang, Lu-Lin, Huang, Timothy, Luo, Wenjie, Xu, Huaxi, Nairn, Angus C., Flajolet, Marc, Ip, Nancy Y., Li, Yue-Ming, Greengard, Paul
Publicado 2021

Lipid droplets in the nervous system

por Ralhan, Isha, Chang, Chi-Lun, Lippincott-Schwartz, Jennifer, Ioannou, Maria S.
Publicado 2021