CD47 blockade enhances the efficacy of intratumoral STING-targeting therapy by activating phagocytes

por Kosaka, Akemi, Ishibashi, Kei, Nagato, Toshihiro, Kitamura, Hidemitsu, Fujiwara, Yukio, Yasuda, Syunsuke, Nagata, Marino, Harabuchi, Shohei, Hayashi, Ryusuke, Yajima, Yuki, Ohara, Kenzo, Kumai, Takumi, Aoki, Naoko, Komohara, Yoshihiro, Oikawa, Kensuke, Harabuchi, Yasuaki, Kitada, Masahiro, Kobayashi, Hiroya, Ohkuri, Takayuki
Publicado 2021

EVAP: A two-photon imaging tool to study conformational changes in endogenous Kv2 channels in live tissues

por Thapa, Parashar, Stewart, Robert, Sepela, Rebecka J., Vivas, Oscar, Parajuli, Laxmi K., Lillya, Mark, Fletcher-Taylor, Sebastian, Cohen, Bruce E., Zito, Karen, Sack, Jon T.
Publicado 2021

LPHN2 inhibits vascular permeability by differential control of endothelial cell adhesion

por Camillo, Chiara, Facchinello, Nicola, Villari, Giulia, Mana, Giulia, Gioelli, Noemi, Sandri, Chiara, Astone, Matteo, Tortarolo, Dora, Clapero, Fabiana, Gays, Dafne, Oberkersch, Roxana E., Arese, Marco, Tamagnone, Luca, Valdembri, Donatella, Santoro, Massimo M., Serini, Guido
Publicado 2021

Activated PI3Kδ signals compromise plasma cell survival via limiting autophagy and increasing ER stress

por Al Qureshah, Fahd, Sagadiev, Sara, Thouvenel, Christopher D., Liu, Shuozhi, Hua, Zhaolin, Hou, Baidong, Acharya, Mridu, James, Richard G., Rawlings, David J.
Publicado 2021

MicroRNA-directed pathway discovery elucidates an miR-221/222–mediated regulatory circuit in class switch recombination

por Wigton, Eric J., Mikami, Yohei, McMonigle, Ryan J., Castellanos, Carlos A., Wade-Vallance, Adam K., Zhou, Simon K., Kageyama, Robin, Litterman, Adam, Roy, Suparna, Kitamura, Daisuke, Dykhuizen, Emily C., Allen, Christopher D.C., Hu, Hui, O’Shea, John J., Ansel, K. Mark
Publicado 2021

Glypican 4 mediates Wnt transport between germ layers via signaling filopodia

por Hu, Bo, Rodriguez, Juan J., Kakkerla Balaraju, Anurag, Gao, Yuanyuan, Nguyen, Nhan T., Steen, Heston, Suhaib, Saeb, Chen, Songhai, Lin, Fang
Publicado 2021

Minibrain kinase and calcineurin coordinate activity-dependent bulk endocytosis through synaptojanin

por Peng, Yi-Jheng, Geng, Junhua, Wu, Ying, Pinales, Cristian, Langen, Jennifer, Chang, Yen-Ching, Buser, Christopher, Chang, Karen T.
Publicado 2021

Electrophysiological characterization of the hERG R56Q LQTS variant and targeted rescue by the activator RPR260243

por Kemp, Jacob M., Whittaker, Dominic G., Venkateshappa, Ravichandra, Pang, ZhaoKai, Johal, Raj, Sergeev, Valentine, Tibbits, Glen F., Mirams, Gary R., Claydon, Thomas W.
Publicado 2021

Synchrony of sarcomeric movement regulates left ventricular pump function in the in vivo beating mouse heart

por Kobirumaki-Shimozawa, Fuyu, Shimozawa, Togo, Oyama, Kotaro, Baba, Shunsuke, Li, Jia, Nakanishi, Tomohiro, Terui, Takako, Louch, William E., Ishiwata, Shin’ichi, Fukuda, Norio
Publicado 2021

Ye Tian: Surveilling stress to live longer

por Morgado-Palacin, Lucia
Publicado 2021

A fungal antigenic driver for Löfgren’s syndrome sarcoidosis

por Lim, Clarice X., Weichhart, Thomas
Publicado 2021

Persistent RNA virus infection is short-lived at the single-cell level but leaves transcriptomic footprints

por Reuther, Peter, Martin, Katrin, Kreutzfeldt, Mario, Ciancaglini, Matias, Geier, Florian, Calabrese, Diego, Merkler, Doron, Pinschewer, Daniel D.
Publicado 2021

Blood transcriptomics reveal the evolution and resolution of the immune response in tuberculosis

por Tabone, Olivier, Verma, Raman, Singhania, Akul, Chakravarty, Probir, Branchett, William J., Graham, Christine M., Lee, Jo, Trang, Tran, Reynier, Frederic, Leissner, Philippe, Kaiser, Karine, Rodrigue, Marc, Woltmann, Gerrit, Haldar, Pranabashis, O’Garra, Anne
Publicado 2021

Correction: Early nasal type I IFN immunity against SARS-CoV-2 is compromised in patients with autoantibodies against type I IFNs

por Lopez, Jonathan, Mommert, Marine, Mouton, William, Pizzorno, Andrés, Brengel-Pesce, Karen, Mezidi, Mehdi, Villard, Marine, Lina, Bruno, Richard, Jean-Christophe, Fassier, Jean-Baptiste, Cheynet, Valérie, Padey, Blandine, Duliere, Victoria, Julien, Thomas, Paul, Stéphane, Bastard, Paul, Belot, Alexandre, Bal, Antonin, Casanova, Jean-Laurent, Rosa-Calatrava, Manuel, Morfin, Florence, Walzer, Thierry, Trouillet-Assant, Sophie
Publicado 2021

The modified mitochondrial outer membrane carrier MTCH2 links mitochondrial fusion to lipogenesis

por Labbé, Katherine, Mookerjee, Shona, Le Vasseur, Maxence, Gibbs, Eddy, Lerner, Chad, Nunnari, Jodi
Publicado 2021

Persistent DNA damage signaling and DNA polymerase theta promote broken chromosome segregation

por Clay, Delisa E., Bretscher, Heidi S., Jezuit, Erin A., Bush, Korie B., Fox, Donald T.
Publicado 2021

Maternal gut microbiome regulates immunity to RSV infection in offspring

por Fonseca, Wendy, Malinczak, Carrie-Anne, Fujimura, Kei, Li, Danny, McCauley, Kathryn, Li, Jia, Best, Shannon K.K., Zhu, Diana, Rasky, Andrew J., Johnson, Christine C., Bermick, Jennifer, Zoratti, Edward M., Ownby, Dennis, Lynch, Susan V., Lukacs, Nicholas W., Ptaschinski, Catherine
Publicado 2021

Single-particle cryo-EM reveals conformational variability of the oligomeric VCC β-barrel pore in a lipid bilayer

por Sengupta, Nayanika, Mondal, Anish Kumar, Mishra, Suman, Chattopadhyay, Kausik, Dutta, Somnath
Publicado 2021

Neuronal activity regulates the nuclear proteome to promote activity-dependent transcription

por Herbst, Wendy A., Deng, Weixian, Wohlschlegel, James A., Achiro, Jennifer M., Martin, Kelsey C.
Publicado 2021

Targeting EYA2 tyrosine phosphatase activity in glioblastoma stem cells induces mitotic catastrophe

por Zhang, Guoxin, Dong, Zhen, Gimple, Ryan C., Wolin, Arthur, Wu, Qiulian, Qiu, Zhixin, Wood, Lisa M., Shen, Jia Z., Jiang, Li, Zhao, Linjie, Lv, Deguan, Prager, Briana C., Kim, Leo J.Y., Wang, Xiuxing, Zhang, Lingdi, Anderson, Ryan L., Moore, Jeffrey K., Bao, Shideng, Keller, Thomas H., Lin, Grace, Kang, Congbao, Hamerlik, Petra, Zhao, Rui, Ford, Heide L., Rich, Jeremy N.
Publicado 2021