Gut microbiota–driven brain Aβ amyloidosis in mice requires microglia

por Dodiya, Hemraj B., Lutz, Holly L., Weigle, Ian Q., Patel, Priyam, Michalkiewicz, Julia, Roman-Santiago, Carlos J., Zhang, Can Martin, Liang, Yingxia, Srinath, Abhinav, Zhang, Xulun, Xia, Jessica, Olszewski, Monica, Zhang, Xiaoqiong, Schipma, Matthew John, Chang, Eugene B., Tanzi, Rudolph E., Gilbert, Jack A., Sisodia, Sangram S.
Publicado 2021

pVHL-mediated SMAD3 degradation suppresses TGF-β signaling

por Zhou, Jun, Dabiri, Yasamin, Gama-Brambila, Rodrigo A., Ghafoory, Shahrouz, Altinbay, Mukaddes, Mehrabi, Arianeb, Golriz, Mohammad, Blagojevic, Biljana, Reuter, Stefanie, Han, Kang, Seidel, Anna, Đikić, Ivan, Wölfl, Stefan, Cheng, Xinlai
Publicado 2021

Reticulon-like REEP4 at the inner nuclear membrane promotes nuclear pore complex formation

por Golchoubian, Banafsheh, Brunner, Andreas, Bragulat-Teixidor, Helena, Neuner, Annett, Akarlar, Busra A., Ozlu, Nurhan, Schlaitz, Anne-Lore
Publicado 2021

Endosomal escape of delivered mRNA from endosomal recycling tubules visualized at the nanoscale

por Paramasivam, Prasath, Franke, Christian, Stöter, Martin, Höijer, Andreas, Bartesaghi, Stefano, Sabirsh, Alan, Lindfors, Lennart, Arteta, Marianna Yanez, Dahlén, Anders, Bak, Annette, Andersson, Shalini, Kalaidzidis, Yannis, Bickle, Marc, Zerial, Marino
Publicado 2021

NFAT-dependent and -independent exhaustion circuits program maternal CD8 T cell hypofunction in pregnancy

por Lewis, Emma L., Xu, Rong, Beltra, Jean-Christophe, Ngiow, Shin Foong, Cohen, Jordana, Telange, Rahul, Crane, Alexander, Sawinski, Deirdre, Wherry, E. John, Porrett, Paige M.
Publicado 2021

Worms find PEZO-1’s function easy to swallow

por Short, Ben
Publicado 2021

Structural basis of the super- and hyper-relaxed states of myosin II

por Craig, Roger, Padrón, Raúl
Publicado 2021

Chromosome compartmentalization alterations in prostate cancer cell lines model disease progression

por San Martin, Rebeca, Das, Priyojit, Dos Reis Marques, Renata, Xu, Yang, Roberts, Justin M., Sanders, Jacob T., Golloshi, Rosela, McCord, Rachel Patton
Publicado 2021

Intravenous administration of BCG protects mice against lethal SARS-CoV-2 challenge

por Hilligan, Kerry L., Namasivayam, Sivaranjani, Clancy, Chad S., O’Mard, Danielle, Oland, Sandra D., Robertson, Shelly J., Baker, Paul J., Castro, Ehydel, Garza, Nicole L., Lafont, Bernard A.P., Johnson, Reed, Ronchese, Franca, Mayer-Barber, Katrin D., Best, Sonja M., Sher, Alan
Publicado 2021

IFT trains overcome an NPHP module barrier at the transition zone

por Park, Kwangjin, Leroux, Michel R.
Publicado 2021

The ides of MARCH5: The E3 ligase essential for peroxisome degradation by pexophagy

por Platta, Harald W., Erdmann, Ralf
Publicado 2021

P2RY8 variants in lupus patients uncover a role for the receptor in immunological tolerance

por He, Yuke, Gallman, Antonia E., Xie, Chengmei, Shen, Qian, Ma, Jianyang, Wolfreys, Finn D., Sandy, Moriah, Arsov, Todor, Wu, Xiaoqian, Qin, Yuting, Zhang, Pingjing, Jiang, Simon, Stanley, Maurice, Wu, Philip, Tan, Jingjing, Ding, Huihua, Xue, Haiyan, Chen, Wei, Xu, Jinping, Criswell, Lindsey A., Nititham, Joanne, Adamski, Marcin, Kitching, A. Richard, Cook, Matthew C., Cao, Lanfang, Shen, Nan, Cyster, Jason G., Vinuesa, Carola G.
Publicado 2021

“P(2)RY(8)-son” break of tolerance promotes SLE

por Tusseau, Maud, Belot, Alexandre
Publicado 2021

TBK1 recruitment to STING mediates autoinflammatory arthritis caused by defective DNA clearance

por Li, Tong, Yum, Seoyun, Li, Minghao, Chen, Xiang, Zuo, Xiaoxia, Chen, Zhijian J.
Publicado 2021

Inhibitory pattern recognition receptors

por Rumpret, Matevž, von Richthofen, Helen J., Peperzak, Victor, Meyaard, Linde
Publicado 2021

Catecholamines are key modulators of ventricular repolarization patterns in the ball python (Python regius)

por Boukens, Bastiaan J.D., Joyce, William, Kristensen, Ditte Lind, Hooijkaas, Ingeborg, Jongejan, Aldo, Wang, Tobias, Jensen, Bjarke
Publicado 2021

Acute exposure to extracellular BTP2 does not inhibit Ca(2+) release during EC coupling in intact skeletal muscle fibers

por Wei-LaPierre, Lan, Groom, Linda, Dirksen, Robert T.
Publicado 2021

Trav15-dv6 family Tcrd rearrangements diversify the Tcra repertoire

por Dauphars, Danielle J., Mihai, Ariana, Wang, Liuyang, Zhuang, Yuan, Krangel, Michael S.
Publicado 2021

B cell–intrinsic TBK1 is essential for germinal center formation during infection and vaccination in mice

por Lee, Michelle S.J., Inoue, Takeshi, Ise, Wataru, Matsuo-Dapaah, Julia, Wing, James B., Temizoz, Burcu, Kobiyama, Kouji, Hayashi, Tomoya, Patil, Ashwini, Sakaguchi, Shimon, Simon, A. Katharina, Bezbradica, Jelena S., Nagatoishi, Satoru, Tsumoto, Kouhei, Inoue, Jun-Ichiro, Akira, Shizuo, Kurosaki, Tomohiro, Ishii, Ken J., Coban, Cevayir
Publicado 2021

Failures in thymus medulla regeneration during immune recovery cause tolerance loss and prime recipients for auto-GVHD

por Alawam, Abdullah S., Cosway, Emilie J., James, Kieran D., Lucas, Beth, Bacon, Andrea, Parnell, Sonia M., White, Andrea J., Jenkinson, William E., Anderson, Graham
Publicado 2021