Neuronal KCNQ2/3 channels are recruited to lipid raft microdomains by palmitoylation of BACE1

por Dai, Gucan
Publicado 2022

Fyn and TOM1L1 are recruited to clathrin-coated pits and regulate Akt signaling

por Cabral-Dias, Rebecca, Lucarelli, Stefanie, Zak, Karolina, Rahmani, Sadia, Judge, Gurjeet, Abousawan, John, DiGiovanni, Laura F., Vural, Dafne, Anderson, Karen E., Sugiyama, Michael G., Genc, Gizem, Hong, Wanjin, Botelho, Roberto J., Fairn, Gregory D., Kim, Peter K., Antonescu, Costin N.
Publicado 2022

The aryl hydrocarbon receptor contributes to tissue adaptation of intestinal eosinophils in mice

por Diny, Nicola Laura, Schonfeldova, Barbora, Shapiro, Michael, Winder, Matthew L., Varsani-Brown, Sunita, Stockinger, Brigitta
Publicado 2022

2022

por Eisner, David A.
Publicado 2022

Hippocampal neurons maintain a large PtdIns(4)P pool that results in faster PtdIns(4,5)P(2) synthesis

por de la Cruz, Lizbeth, Kushmerick, Christopher, Sullivan, Jane M., Kruse, Martin, Vivas, Oscar
Publicado 2022

Troponin levels make a difference

por Short, Ben
Publicado 2022

Monocytic MDSCs homing to thymus contribute to age-related CD8(+) T cell tolerance of HBV

por Fang, Zhong, Zhang, Yi, Zhu, Zhaoqin, Wang, Cong, Hu, Yao, Peng, Xiuhua, Zhang, Dandan, Zhao, Jun, Shi, Bisheng, Shen, Zhongliang, Wu, Min, Xu, Chunhua, Chen, Jieliang, Zhou, Xiaohui, Xie, Youhua, Yu, Hui, Zhang, Xiaonan, Li, Jianhua, Hu, Yunwen, Kozlowski, Maya, Bertoletti, Antonio, Yuan, Zhenghong
Publicado 2022

Mechanosensitive calcium flashes promote sustained RhoA activation during tight junction remodeling

por Varadarajan, Saranyaraajan, Chumki, Shahana A., Stephenson, Rachel E., Misterovich, Eileen R., Wu, Jessica L., Dudley, Claire E., Erofeev, Ivan S., Goryachev, Andrew B., Miller, Ann L.
Publicado 2022

FGFR3 overactivation in the brain is responsible for memory impairments in Crouzon syndrome mouse model

por Cornille, Maxence, Moriceau, Stéphanie, Khonsari, Roman H., Heuzé, Yann, Loisay, Léa, Boitez, Valérie, Morice, Anne, Arnaud, Eric, Collet, Corinne, Bensidhoum, Morad, Kaci, Nabil, Boddaert, Nathalie, Paternoster, Giovanna, Rauschendorfer, Theresa, Werner, Sabine, Mansour, Suzanne L., Di Rocco, Federico, Oury, Franck, Legeai-Mallet, Laurence
Publicado 2022

Sidekick dynamically rebalances contractile and protrusive forces to control tissue morphogenesis

por Malin, Jacob, Rosa Birriel, Christian, Astigarraga, Sergio, Treisman, Jessica E., Hatini, Victor
Publicado 2022

A partial form of inherited human USP18 deficiency underlies infection and inflammation

por Martin-Fernandez, Marta, Buta, Sofija, Le Voyer, Tom, Li, Zhi, Dynesen, Lasse Toftdal, Vuillier, Françoise, Franklin, Lina, Ailal, Fatima, Muglia Amancio, Alice, Malle, Louise, Gruber, Conor, Benhsaien, Ibtihal, Altman, Jennie, Taft, Justin, Deswarte, Caroline, Roynard, Manon, Nieto-Patlan, Alejandro, Moriya, Kunihiko, Rosain, Jérémie, Boddaert, Nathalie, Bousfiha, Aziz, Crow, Yanick J., Jankovic, Dragana, Sher, Alan, Casanova, Jean-Laurent, Pellegrini, Sandra, Bustamante, Jacinta, Bogunovic, Dusan
Publicado 2022

Functional vulnerability of liver macrophages to capsules defines virulence of blood-borne bacteria

por An, Haoran, Qian, Chenyun, Huang, Yijia, Li, Jing, Tian, Xianbin, Feng, Jiaying, Hu, Jiao, Fang, Yujie, Jiao, Fangfang, Zeng, Yuna, Huang, Xueting, Meng, Xianbin, Liu, Xue, Lin, Xin, Zeng, Zhutian, Guilliams, Martin, Beschin, Alain, Chen, Yongwen, Wu, Yuzhang, Wang, Jing, Oggioni, Marco Rinaldo, Leong, John, Veening, Jan-Willem, Deng, Haiteng, Zhang, Rong, Wang, Hui, Wu, Jiang, Cui, Yan, Zhang, Jing-Ren
Publicado 2022

Ferrous iron–activatable drug conjugate achieves potent MAPK blockade in KRAS-driven tumors

por Jiang, Honglin, Muir, Ryan K., Gonciarz, Ryan L., Olshen, Adam B., Yeh, Iwei, Hann, Byron C., Zhao, Ning, Wang, Yung-hua, Behr, Spencer C., Korkola, James E., Evans, Michael J., Collisson, Eric A., Renslo, Adam R.
Publicado 2022

The multi-factor modulated biogenesis of the mitochondrial multi-span protein Om14

por Zhou, Jialin, Jung, Martin, Dimmer, Kai S., Rapaport, Doron
Publicado 2022

In situ cryo-electron tomography reveals local cellular machineries for axon branch development

por Nedozralova, Hana, Basnet, Nirakar, Ibiricu, Iosune, Bodakuntla, Satish, Biertümpfel, Christian, Mizuno, Naoko
Publicado 2022

DNA damage contributes to neurotoxic inflammation in Aicardi-Goutières syndrome astrocytes

por Giordano, Anna Maria Sole, Luciani, Marco, Gatto, Francesca, Abou Alezz, Monah, Beghè, Chiara, Della Volpe, Lucrezia, Migliara, Alessandro, Valsoni, Sara, Genua, Marco, Dzieciatkowska, Monika, Frati, Giacomo, Tahraoui-Bories, Julie, Giliani, Silvia Clara, Orcesi, Simona, Fazzi, Elisa, Ostuni, Renato, D’Alessandro, Angelo, Di Micco, Raffaella, Merelli, Ivan, Lombardo, Angelo, Reijns, Martin A.M., Gromak, Natalia, Gritti, Angela, Kajaste-Rudnitski, Anna
Publicado 2022

PERK reprograms hematopoietic progenitor cells to direct tumor-promoting myelopoiesis in the spleen

por Liu, Mingyu, Wu, Chong, Luo, Shufeng, Hua, Qiaomin, Chen, Hai-Tian, Weng, Yulan, Xu, Junyu, Lin, Huiling, Wang, Lu, Li, Jinheng, Zhu, Lan, Guo, Zhenhong, Zhuang, Shi-Mei, Kang, Tiebang, Zheng, Limin
Publicado 2022

The E3 ligase TRIM1 ubiquitinates LRRK2 and controls its localization, degradation, and toxicity

por Stormo, Adrienne E.D., Shavarebi, Farbod, FitzGibbon, Molly, Earley, Elizabeth M., Ahrendt, Hannah, Lum, Lotus S., Verschueren, Erik, Swaney, Danielle L., Skibinski, Gaia, Ravisankar, Abinaya, van Haren, Jeffrey, Davis, Emily J., Johnson, Jeffrey R., Von Dollen, John, Balen, Carson, Porath, Jacob, Crosio, Claudia, Mirescu, Christian, Iaccarino, Ciro, Dauer, William T., Nichols, R. Jeremy, Wittmann, Torsten, Cox, Timothy C., Finkbeiner, Steve, Krogan, Nevan J., Oakes, Scott A., Hiniker, Annie
Publicado 2022

Iron out KRAS-driven cancer

por Lei, Guang, Gan, Boyi
Publicado 2022

Cdc14 spatiotemporally dephosphorylates Atg13 to activate autophagy during meiotic divisions

por Feng, Wenzhi, Argüello-Miranda, Orlando, Qian, Suhong, Wang, Fei
Publicado 2022