Cytosolic Ca(2+)-dependent Ca(2+) release activity primarily determines the ER Ca(2+) level in cells expressing the CPVT-linked mutant RYR2

por Kurebayashi, Nagomi, Murayama, Takashi, Ota, Ryosaku, Suzuki, Junji, Kanemaru, Kazunori, Kobayashi, Takuya, Ohno, Seiko, Horie, Minoru, Iino, Masamitsu, Yamashita, Fumiyoshi, Sakurai, Takashi
Publicado 2022

A mathematical model to quantify RYR Ca(2+) leak and associated heat production in resting human skeletal muscle fibers

por Barclay, Christopher J., Launikonis, Bradley S.
Publicado 2022

Calcium current modulation by the γ(1) subunit depends on alternative splicing of Ca(V)1.1

por El Ghaleb, Yousra, Ortner, Nadine J., Posch, Wilfried, Fernández-Quintero, Monica L., Tuinte, Wietske E., Monteleone, Stefania, Draheim, Henning J., Liedl, Klaus R., Wilflingseder, Doris, Striessnig, Jörg, Tuluc, Petronel, Flucher, Bernhard E., Campiglio, Marta
Publicado 2022

Heart failure in mice induces a dysfunction of the sinus node associated with reduced CaMKII signaling

por Xue, Jian-Bin, Val-Blasco, Almudena, Davoodi, Moran, Gómez, Susana, Yaniv, Yael, Benitah, Jean-Pierre, Gómez, Ana María
Publicado 2022

High-efficiency nonviral CRISPR/Cas9-mediated gene editing of human T cells using plasmid donor DNA

por Oh, Soyoung A., Senger, Kate, Madireddi, Shravan, Akhmetzyanova, Ilseyar, Ishizuka, Isabel E., Tarighat, Somayeh, Lo, Jerry H., Shaw, David, Haley, Benjamin, Rutz, Sascha
Publicado 2022

Visualizing intra-Golgi localization and transport by side-averaging Golgi ministacks

por Tie, Hieng Chiong, Mahajan, Divyanshu, Lu, Lei
Publicado 2022

The archaeal glutamate transporter homologue Glt(Ph) shows heterogeneous substrate binding

por Reddy, Krishna D., Ciftci, Didar, Scopelliti, Amanda J., Boudker, Olga
Publicado 2022

In vivo labeling reveals continuous trafficking of TCF-1(+) T cells between tumor and lymphoid tissue

por Li, Zhi, Tuong, Zewen K., Dean, Isaac, Willis, Claire, Gaspal, Fabrina, Fiancette, Rémi, Idris, Suaad, Kennedy, Bethany, Ferdinand, John R., Peñalver, Ana, Cabantous, Mia, Murtuza Baker, Syed, Fry, Jeremy W., Carlesso, Gianluca, Hammond, Scott A., Dovedi, Simon J., Hepworth, Matthew R., Clatworthy, Menna R., Withers, David R.
Publicado 2022

Lineage tracing clarifies the cellular origin of tissue-resident macrophages in the developing heart

por Liu, Kuo, Jin, Hengwei, Tang, Muxue, Zhang, Shaohua, Tian, Xueying, Zhang, Mingjun, Han, Ximeng, Liu, Xiuxiu, Tang, Juan, Pu, Wenjuan, Li, Yan, He, Lingjuan, Yang, Zhongzhou, Lui, Kathy O., Zhou, Bin
Publicado 2022

Biological noise is a key determinant of the reproducibility and adaptability of cardiac pacemaking and EC coupling

por Guarina, Laura, Moghbel, Ariana Neelufar, Pourhosseinzadeh, Mohammad S., Cudmore, Robert H., Sato, Daisuke, Clancy, Colleen E., Santana, Luis Fernando
Publicado 2022

Interphase microtubule disassembly is a signaling cue that drives cell rounding at mitotic entry

por Leguay, Kévin, Decelle, Barbara, Elkholi, Islam E., Bouvier, Michel, Côté, Jean-François, Carréno, Sébastien
Publicado 2022

Trapping of CDC42 C-terminal variants in the Golgi drives pyrin inflammasome hyperactivation

por Nishitani-Isa, Masahiko, Mukai, Kojiro, Honda, Yoshitaka, Nihira, Hiroshi, Tanaka, Takayuki, Shibata, Hirofumi, Kodama, Kumi, Hiejima, Eitaro, Izawa, Kazushi, Kawasaki, Yuri, Osawa, Mitsujiro, Katata, Yu, Onodera, Sachiko, Watanabe, Tatsuya, Uchida, Takashi, Kure, Shigeo, Takita, Junko, Ohara, Osamu, Saito, Megumu K., Nishikomori, Ryuta, Taguchi, Tomohiko, Sasahara, Yoji, Yasumi, Takahiro
Publicado 2022

Endomembranes promote chromosome missegregation by ensheathing misaligned chromosomes

por Ferrandiz, Nuria, Downie, Laura, Starling, Georgina P., Royle, Stephen J.
Publicado 2022

A strategy for determining the equilibrium constants for heteromeric ion channels in a complex model

por Benndorf, Klaus, Eick, Thomas, Sattler, Christian, Schmauder, Ralf, Schulz, Eckhard
Publicado 2022

SHIP164 is a chorein motif lipid transfer protein that controls endosome–Golgi membrane traffic

por Hanna, Michael G., Suen, Patreece H., Wu, Yumei, Reinisch, Karin M., De Camilli, Pietro
Publicado 2022

Null IFNAR1 and IFNAR2 alleles are surprisingly common in the Pacific and Arctic

por Meyts, Isabelle
Publicado 2022

The X in seX-biased immunity and autoimmune rheumatic disease

por Jiwrajka, Nikhil, Anguera, Montserrat C.
Publicado 2022

V-ATPase is a universal regulator of LC3-associated phagocytosis and non-canonical autophagy

por Hooper, Kirsty M., Jacquin, Elise, Li, Taoyingnan, Goodwin, Jonathan M., Brumell, John H., Durgan, Joanne, Florey, Oliver
Publicado 2022

Inhibition of FGF receptor blocks adaptive resistance to RET inhibition in CCDC6-RET–rearranged thyroid cancer

por Raman, Renuka, Villefranc, Jacques A., Ullmann, Timothy M., Thiesmeyer, Jessica, Anelli, Viviana, Yao, Jun, Hurley, James R., Pauli, Chantal, Bareja, Rohan, Wha Eng, Kenneth, Dorsaint, Princesca, Wilkes, David C., Beg, Shaham, Kudman, Sarah, Shaw, Reid, Churchill, Michael, Ahmed, Adnan, Keefer, Laurel, Misner, Ian, Nichol, Donna, Gumpeni, Naveen, Scognamiglio, Theresa, Rubin, Mark A., Grandori, Carla, Solomon, James Patrick, Song, Wei, Mosquera, Juan Miguel, Dephoure, Noah, Sboner, Andrea, Elemento, Olivier, Houvras, Yariv
Publicado 2022

STING controls energy stress-induced autophagy and energy metabolism via STX17

por Rong, Yueguang, Zhang, Shen, Nandi, Nilay, Wu, Zhe, Li, Linsen, Liu, Yang, Wei, Yuehan, Zhao, Yuan, Yuan, Weigang, Zhou, Chuchu, Xiao, Guanghua, Levine, Beth, Yan, Nan, Mou, Shan, Deng, Liufu, Tang, Zaiming, Liu, Xiaoxia, Kramer, Helmut, Zhong, Qing
Publicado 2022