Conformational transitions of the Spindly adaptor underlie its interaction with Dynein and Dynactin

por d’Amico, Ennio A., Ud Din Ahmad, Misbha, Cmentowski, Verena, Girbig, Mathias, Müller, Franziska, Wohlgemuth, Sabine, Brockmeyer, Andreas, Maffini, Stefano, Janning, Petra, Vetter, Ingrid R., Carter, Andrew P., Perrakis, Anastassis, Musacchio, Andrea
Publicado 2022

Endosomal recycling defects link Huntington’s disease with McLeod syndrome

por Marsan, Elise, Huang, Eric J.
Publicado 2022

Spatiotemporal control of actomyosin contractility by MRCKβ signaling drives phagocytosis

por Zihni, Ceniz, Georgiadis, Anastasios, Ramsden, Conor M., Sanchez-Heras, Elena, Haas, Alexis J., Nommiste, Britta, Semenyuk, Olha, Bainbridge, James W.B., Coffey, Peter J., Smith, Alexander J., Ali, Robin R., Balda, Maria S., Matter, Karl
Publicado 2022

Autoantibodies against type I IFNs in patients with critical influenza pneumonia

por Zhang, Qian, Pizzorno, Andrés, Miorin, Lisa, Bastard, Paul, Gervais, Adrian, Le Voyer, Tom, Bizien, Lucy, Manry, Jeremy, Rosain, Jérémie, Philippot, Quentin, Goavec, Kelian, Padey, Blandine, Cupic, Anastasija, Laurent, Emilie, Saker, Kahina, Vanker, Martti, Särekannu, Karita, García-Salum, Tamara, Ferres, Marcela, Le Corre, Nicole, Sánchez-Céspedes, Javier, Balsera-Manzanero, María, Carratala, Jordi, Retamar-Gentil, Pilar, Abelenda-Alonso, Gabriela, Valiente, Adoración, Tiberghien, Pierre, Zins, Marie, Debette, Stéphanie, Meyts, Isabelle, Haerynck, Filomeen, Castagnoli, Riccardo, Notarangelo, Luigi D., Gonzalez-Granado, Luis I., Dominguez-Pinilla, Nerea, Andreakos, Evangelos, Triantafyllia, Vasiliki, Rodríguez-Gallego, Carlos, Solé-Violán, Jordi, Ruiz-Hernandez, José Juan, Rodríguez de Castro, Felipe, Ferreres, José, Briones, Marisa, Wauters, Joost, Vanderbeke, Lore, Feys, Simon, Kuo, Chen-Yen, Lei, Wei-Te, Ku, Cheng-Lung, Tal, Galit, Etzioni, Amos, Hanna, Suhair, Fournet, Thomas, Casalegno, Jean-Sebastien, Queromes, Gregory, Argaud, Laurent, Javouhey, Etienne, Rosa-Calatrava, Manuel, Cordero, Elisa, Aydillo, Teresa, Medina, Rafael A., Kisand, Kai, Puel, Anne, Jouanguy, Emmanuelle, Abel, Laurent, Cobat, Aurélie, Trouillet-Assant, Sophie, García-Sastre, Adolfo, Casanova, Jean-Laurent
Publicado 2022

Triglyceride lipolysis triggers liquid crystalline phases in lipid droplets and alters the LD proteome

por Rogers, Sean, Gui, Long, Kovalenko, Anastasiia, Zoni, Valeria, Carpentier, Maxime, Ramji, Kamran, Ben Mbarek, Kalthoum, Bacle, Amelie, Fuchs, Patrick, Campomanes, Pablo, Reetz, Evan, Speer, Natalie Ortiz, Reynolds, Emma, Thiam, Abdou Rachid, Vanni, Stefano, Nicastro, Daniela, Henne, W. Mike
Publicado 2022

Mitochondria transfer mediates stress erythropoiesis by altering the bioenergetic profiles of early erythroblasts through CD47

por Yang, Chong, Yokomori, Rui, Chua, Lee Hui, Tan, Shi Hao, Tan, Darren Qiancheng, Miharada, Kenichi, Sanda, Takaomi, Suda, Toshio
Publicado 2022

NCOA4: More than a receptor for ferritinophagy

por Wang, Zheng, Zhang, Hong
Publicado 2022

Balancing cell polarity PARts through dephosphorylation

por Barros-Carvalho, André, Morais-de-Sá, Eurico
Publicado 2022

Intestinal epithelial c-Maf expression determines enterocyte differentiation and nutrient uptake in mice

por Cosovanu, Catalina, Resch, Philipp, Jordan, Stefan, Lehmann, Andrea, Ralser, Markus, Farztdinov, Vadim, Spranger, Joachim, Mülleder, Michael, Brachs, Sebastian, Neumann, Christian
Publicado 2022

c-MAF coordinates enterocyte zonation and nutrient uptake transcriptional programs

por González-Loyola, Alejandra, Bernier-Latmani, Jeremiah, Roci, Irena, Wyss, Tania, Langer, Jakob, Durot, Stephan, Munoz, Olivia, Prat-Luri, Borja, Delorenzi, Mauro, Lutolf, Matthias P., Zamboni, Nicola, Verdeil, Grégory, Petrova, Tatiana V.
Publicado 2022

Junctophilins 1, 2, and 3 all support voltage-induced Ca(2+) release despite considerable divergence

por Perni, Stefano, Beam, Kurt
Publicado 2022

Recycling of cell surface membrane proteins from yeast endosomes is regulated by ubiquitinated Ist1

por Laidlaw, Kamilla M.E., Calder, Grant, MacDonald, Chris
Publicado 2022

Sleep exerts lasting effects on hematopoietic stem cell function and diversity

por McAlpine, Cameron S., Kiss, Máté G., Zuraikat, Faris M., Cheek, David, Schiroli, Giulia, Amatullah, Hajera, Huynh, Pacific, Bhatti, Mehreen Z., Wong, Lai-Ping, Yates, Abi G., Poller, Wolfram C., Mindur, John E., Chan, Christopher T., Janssen, Henrike, Downey, Jeffrey, Singh, Sumnima, Sadreyev, Ruslan I., Nahrendorf, Matthias, Jeffrey, Kate L., Scadden, David T., Naxerova, Kamila, St-Onge, Marie-Pierre, Swirski, Filip K.
Publicado 2022

Viral proteases activate the CARD8 inflammasome in the human cardiovascular system

por Nadkarni, Rhea, Chu, Wern Cui, Lee, Cheryl Q.E., Mohamud, Yasir, Yap, Lynn, Toh, Gee Ann, Beh, Sheryl, Lim, Radiance, Fan, Yiyun Michelle, Zhang, Yizhuo Lyanne, Robinson, Kim, Tryggvason, Karl, Luo, Honglin, Zhong, Franklin, Ho, Lena
Publicado 2022

ARL3 mediates BBSome ciliary turnover by promoting its outward movement across the transition zone

por Liu, Yan-Xia, Sun, Wei-Yue, Xue, Bin, Zhang, Rui-Kai, Li, Wen-Juan, Xie, Xixian, Fan, Zhen-Chuan
Publicado 2022

Impaired immune response drives age-dependent severity of COVID-19

por Beer, Julius, Crotta, Stefania, Breithaupt, Angele, Ohnemus, Annette, Becker, Jan, Sachs, Benedikt, Kern, Lisa, Llorian, Miriam, Ebert, Nadine, Labroussaa, Fabien, Nhu Thao, Tran Thi, Trueeb, Bettina Salome, Jores, Joerg, Thiel, Volker, Beer, Martin, Fuchs, Jonas, Kochs, Georg, Wack, Andreas, Schwemmle, Martin, Schnepf, Daniel
Publicado 2022

Inhibition of GABA(A) receptors in intestinal stem cells prevents chemoradiotherapy-induced intestinal toxicity

por Zhang, Cuiyu, Zhou, Yuping, Zheng, Junjie, Ning, Nannan, Liu, Haining, Jiang, Wenyang, Yu, Xin, Mu, Kun, Li, Yan, Guo, Wei, Hu, Huili, Li, Jingxin, Chen, Dawei
Publicado 2022

The low-density lipoprotein receptor–mTORC1 axis coordinates CD8(+) T cell activation

por Bonacina, Fabrizia, Moregola, Annalisa, Svecla, Monika, Coe, David, Uboldi, Patrizia, Fraire, Sara, Beretta, Simona, Beretta, Giangiacomo, Pellegatta, Fabio, Catapano, Alberico Luigi, Marelli-Berg, Federica M., Norata, Giuseppe Danilo
Publicado 2022

A specialized tyrosine-based endocytosis signal in MR1 controls antigen presentation to MAIT cells

por Lim, Hui Jing, Wubben, Jacinta M., Garcia, Cristian Pinero, Cruz-Gomez, Sebastian, Deng, Jieru, Mak, Jeffrey Y.W., Hachani, Abderrahman, Anderson, Regan J., Painter, Gavin F., Goyette, Jesse, Amarasinghe, Shanika L., Ritchie, Matthew E., Roquilly, Antoine, Fairlie, David P., Gaus, Katharina, Rossjohn, Jamie, Villadangos, Jose A., McWilliam, Hamish E.G.
Publicado 2022

CARD8 makes coxsackievirus more “heartbreaking”

por Wang, Qiankun, Shan, Liang
Publicado 2022