N-terminal truncated cardiac troponin I enhances Frank-Starling response by increasing myofilament sensitivity to resting tension

por Feng, Han-Zhong, Huang, Xupei, Jin, Jian-Ping
Publicado 2023

The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA

por Jaffray, Ellis G., Tatham, Michael H., Mojsa, Barbara, Liczmanska, Magda, Rojas-Fernandez, Alejandro, Yin, Yili, Ball, Graeme, Hay, Ronald T.
Publicado 2023

Tingible body macrophages: Gargantuan chameleons of the germinal center

por Baudon, Elisa Madeleine, Bajenoff, Marc
Publicado 2023

IFNγ score–based neoadjuvant immunotherapy for stage III melanoma

por Fukuda, Keitaro
Publicado 2023

Eye on genome editing

por Du, Samuel W., Palczewski, Krzysztof
Publicado 2023

License to kill: Retinoic acid programs T cells for tissue residency

por Heeg, Maximilian, Goldrath, Ananda W.
Publicado 2023

Spatial mapping reveals granuloma diversity and histopathological superstructure in human tuberculosis

por Sawyer, Andrew J., Patrick, Ellis, Edwards, Jarem, Wilmott, James S., Fielder, Timothy, Yang, Qianting, Barber, Daniel L., Ernst, Joel D., Britton, Warwick J., Palendira, Umaimainthan, Chen, Xinchun, Feng, Carl G.
Publicado 2023

Overexpression of Lmo2 initiates T-lymphoblastic leukemia via impaired thymocyte competition

por Abdulla, Hesham D., Alserihi, Raed, Flensburg, Christoffer, Abeysekera, Waruni, Luo, Meng-Xiao, Gray, Daniel H.D., Liu, Xiaodong, Smyth, Gordon K., Alexander, Warren S., Majewski, Ian J., McCormack, Matthew P.
Publicado 2023

A neomorphic mutation in the interferon activation domain of IRF4 causes a dominant primary immunodeficiency

por Thouenon, Romane, Chentout, Loïc, Moreno-Corona, Nidia, Poggi, Lucie, Lombardi, Emilia Puig, Hoareau, Benedicte, Schmitt, Yohann, Lagresle-Peyrou, Chantal, Bustamante, Jacinta, André, Isabelle, Cavazzana, Marina, Durandy, Anne, Casanova, Jean-Laurent, Galicier, Lionel, Fadlallah, Jehane, Fischer, Alain, Kracker, Sven
Publicado 2023

Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage

por Billiet, Lore, De Cock, Laurenz, Sanchez Sanchez, Guillem, Mayer, Rupert L., Goetgeluk, Glenn, De Munter, Stijn, Pille, Melissa, Ingels, Joline, Jansen, Hanne, Weening, Karin, Pascal, Eva, Raes, Killian, Bonte, Sarah, Kerre, Tessa, Vandamme, Niels, Seurinck, Ruth, Roels, Jana, Lavaert, Marieke, Van Nieuwerburgh, Filip, Leclercq, Georges, Taghon, Tom, Impens, Francis, Menten, Björn, Vermijlen, David, Vandekerckhove, Bart
Publicado 2023

Human germline heterozygous gain-of-function STAT6 variants cause severe allergic disease

por Sharma, Mehul, Leung, Daniel, Momenilandi, Mana, Jones, Lauren C.W., Pacillo, Lucia, James, Alyssa E., Murrell, Jill R., Delafontaine, Selket, Maimaris, Jesmeen, Vaseghi-Shanjani, Maryam, Del Bel, Kate L., Lu, Henry Y., Chua, Gilbert T., Di Cesare, Silvia, Fornes, Oriol, Liu, Zhongyi, Di Matteo, Gigliola, Fu, Maggie P., Amodio, Donato, Tam, Issan Yee San, Chan, Gavin Shueng Wai, Sharma, Ashish A., Dalmann, Joshua, van der Lee, Robin, Blanchard-Rohner, Géraldine, Lin, Susan, Philippot, Quentin, Richmond, Phillip A., Lee, Jessica J., Matthews, Allison, Seear, Michael, Turvey, Alexandra K., Philips, Rachael L., Brown-Whitehorn, Terri F., Gray, Christopher J., Izumi, Kosuke, Treat, James R., Wood, Kathleen H., Lack, Justin, Khleborodova, Asya, Niemela, Julie E., Yang, Xingtian, Liang, Rui, Kui, Lin, Wong, Christina Sze Man, Poon, Grace Wing Kit, Hoischen, Alexander, van der Made, Caspar I., Yang, Jing, Chan, Koon Wing, Rosa Duque, Jaime Sou Da, Lee, Pamela Pui Wah, Ho, Marco Hok Kung, Chung, Brian Hon Yin, Le, Huong Thi Minh, Yang, Wanling, Rohani, Pejman, Fouladvand, Ali, Rokni-Zadeh, Hassan, Changi-Ashtiani, Majid, Miryounesi, Mohammad, Puel, Anne, Shahrooei, Mohammad, Finocchi, Andrea, Rossi, Paolo, Rivalta, Beatrice, Cifaldi, Cristina, Novelli, Antonio, Passarelli, Chiara, Arasi, Stefania, Bullens, Dominique, Sauer, Kate, Claeys, Tania, Biggs, Catherine M., Morris, Emma C., Rosenzweig, Sergio D., O’Shea, John J., Wasserman, Wyeth W., Bedford, H. Melanie, van Karnebeek, Clara D.M., Palma, Paolo, Burns, Siobhan O., Meyts, Isabelle, Casanova, Jean-Laurent, Lyons, Jonathan J., Parvaneh, Nima, Nguyen, Anh Thi Van, Cancrini, Caterina, Heimall, Jennifer, Ahmed, Hanan, McKinnon, Margaret L., Lau, Yu Lung, Béziat, Vivien, Turvey, Stuart E.
Publicado 2023

Vision rescue via unconstrained in vivo prime editing in degenerating neural retinas

por Qin, Huan, Zhang, Wenliang, Zhang, Shiyao, Feng, Yuan, Xu, Weihui, Qi, Jia, Zhang, Qian, Xu, Chunxiu, Liu, Shanshan, Zhang, Jia, Lei, Yushuang, Liu, Wanqin, Feng, Shuyu, Wang, Jingjing, Fu, Xuefei, Xu, Zifen, Li, Ping, Yao, Kai
Publicado 2023

IFN-γ signature enables selection of neoadjuvant treatment in patients with stage III melanoma

por Reijers, Irene L.M., Rao, Disha, Versluis, Judith M., Menzies, Alexander M., Dimitriadis, Petros, Wouters, Michel W., Spillane, Andrew J., Klop, Willem M.C., Broeks, Annegien, Bosch, Linda J.W., Lopez-Yurda, Marta, van Houdt, Winan J., Rawson, Robert V., Grijpink-Ongering, Lindsay G., Gonzalez, Maria, Cornelissen, Sten, Bouwman, Jasper, Sanders, Joyce, Plasmeijer, Elsemieke, Elshot, Yannick S., Scolyer, Richard A., van de Wiel, Bart A., Peeper, Daniel S., van Akkooi, Alexander C.J., Long, Georgina V., Blank, Christian U.
Publicado 2023

Secreted mammalian DNases protect against systemic bacterial infection by digesting biofilms

por Lacey, Keenan A., Serpas, Lee, Makita, Sohei, Wang, Yueyang, Rashidfarrokhi, Ali, Soni, Chetna, Gonzalez, Sandra, Moreira, Andre, Torres, Victor J., Reizis, Boris
Publicado 2023

Human PIK3R1 mutations disrupt lymphocyte differentiation to cause activated PI3Kδ syndrome 2

por Nguyen, Tina, Lau, Anthony, Bier, Julia, Cooke, Kristen C., Lenthall, Helen, Ruiz-Diaz, Stephanie, Avery, Danielle T., Brigden, Henry, Zahra, David, Sewell, William A, Droney, Luke, Okada, Satoshi, Asano, Takaki, Abolhassani, Hassan, Chavoshzadeh, Zahra, Abraham, Roshini S., Rajapakse, Nipunie, Klee, Eric W., Church, Joseph A., Williams, Andrew, Wong, Melanie, Burkhart, Christoph, Uzel, Gulbu, Croucher, David R., James, David E., Ma, Cindy S., Brink, Robert, Tangye, Stuart G., Deenick, Elissa K.
Publicado 2023

cMyBP-C ablation in human engineered cardiac tissue causes progressive Ca(2+)-handling abnormalities

por De Lange, Willem J., Farrell, Emily T., Hernandez, Jonathan J., Stempien, Alana, Kreitzer, Caroline R., Jacobs, Derek R., Petty, Dominique L., Moss, Richard L., Crone, Wendy C., Ralphe, J. Carter
Publicado 2023

Intestinal cell type-specific communication networks underlie homeostasis and response to Western diet

por Wang, Yu-Chen, Cao, Yang, Pan, Calvin, Zhou, Zhiqiang, Yang, Lili, Lusis, Aldons J.
Publicado 2023