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3401“…Here, in rats model we (i)used behavioral-assessment tests to evaluate heat acclimation mediated hypoxic (15’ 4.5 ± 0.5% O(2)) neuroprotection, (ii) measured protein and transcript levels of NMDA-R and AMPA-R subunits before and after hypoxia in the hippocampus and the frontal cortex, to evaluate the role of Ca(2+) in neuro-protection/cross-tolerance. Behavioral tests confirmed hypoxic tolerance in long-term (30d) but not in short-term (2d) heat acclimated rats. …”
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3402“…Study outcomes indicated that schizophrenic patients’ EPP deficits were consistently observed across studies (d = −0.92, 95% CI = −1.06 < δ < −0.78), with identification tasks (d = −0.95, 95% CI = −1.11 < δ < −0.80) being more difficult to process than discrimination tasks (d = −0.74, 95% CI = −1.03 < δ < −0.44) and emotional stimuli being more difficult than neutral stimuli. …”
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3403por Marquié, Marta, Valero, Sergi, Martínez, Joan, Alarcón-Martín, Emilio, García-Sánchez, Ainhoa, de Rojas, Itziar, Castilla-Martí, Miguel, Castilla-Martí, Luis, Hernández, Isabel, Rosende-Roca, Maitée, Vargas, Liliana, Tartari, Juan Pablo, Esteban-De Antonio, Ester, Bojaryn, Urszula, Pytel, Vanesa, Narvaiza, Leire, Alegret, Montserrat, Ortega, Gemma, Espinosa, Ana, Sanabria, Ángela, Pérez-Cordón, Alba, Lleonart, Núria, Muñoz, Nathalia, Tárraga, Lluís, Ruiz, Agustín, Boada, Mercè“…We aimed to investigate differences in macular VD in the superficial plexus in a large cohort of individuals cognitively unimpaired (CU), with mild cognitive impairment due to Alzheimer´s disease (MCI-AD), MCI due to cerebrovascular pathology (MCI-Va), probable Alzheimer´s disease dementia (ADD) and Vascular Dementia (VaD). Clinical, demographical, ophthalmological and OCT-A data from the Neuro-ophthalmology Research at Fundació ACE (NORFACE) project were analyzed. …”
Publicado 2022
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3405por Kumar, Manoj, Nanga, Ravi Prakash Reddy, Verma, Gaurav, Wilson, Neil, Brisset, Jean Christophe, Nath, Kavindra, Chawla, Sanjeev“…In the recent past, the advent and development of more sophisticated metabolic imaging and spectroscopic sequences have revolutionized the field of neuro-oncologic metabolomics. In this review article, we will briefly describe the scientific premises of three-dimensional echoplanar spectroscopic imaging (3D-EPSI), two-dimensional correlation spectroscopy (2D-COSY), and chemical exchange saturation technique (CEST) MRI techniques. …”
Publicado 2022
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3406por Chteinberg, Emil, Sauer, Christopher Martin, Rennspiess, Dorit, Beumers, Lukas, Schiffelers, Lisa, Eben, Jonathan, Haugg, Anke, Winnepenninckx, Véronique, Kurz, Anna Kordelia, Speel, Ernst-Jan, Zenke, Martin, zur Hausen, Axel“…All MCCs were devoid of REST and were positive for NeuroD1 expression. Only one MCC tissue revealed focal ASCL1 expression. …”
Publicado 2018
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3407“…The tissue sections were stained with hemotoxylin-eosin and immunostained for chromogranin A (CgA), serotonin, peptide YY (PYY), oxyntomodulin, pancreatic polypeptide (PP), somatostatin, Musashi1 (Msi1), Math1, Neurogenin3 (Neurog3) and NeuroD1. The staining was quantified using image analysis software. …”
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3408“…All five patients with confirmed adrenal insufficiency with cortisol levels <3 mcg/dL were treated with corticosteroids. 22 patients had cortisol levels in the equivocal zone (3 to 15 mcg/dL), and 16 were treated with corticosteroids. …”
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3409por Fujiwara, Mariana Tazima, Daniel, Karla Borges, Trentin, Marília Bortolotto Felippe, Cerci, Murilo Oliveira, Garmes, Heraldo Mendes“…At that time, neuroimaging had shown a pituitary enlargement, and laboratory data were diagnostic of severe primary hypothyroidism with TSH of 290.6 uUI/mL (normal range 0.4 to 4.5 uUI/mL) and T4L <0.23 ng/dL (normal range: 0.9 to 1.8 ng/dL). She then had received a 75 mcg levothyroxine prescription. …”
Publicado 2021
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3410por Onose, G, Mureşanu, DF, Ciurea, AV, Chendreanu, CD, Mihaescu, AS, Mardare, DC, Andone, I, SpȦnu, A, Popescu, C, Dumitrescu, A, Popescu, M, Grigorean, V, Ungur, B, Marinescu, F, Colibaşeanu, I, Onose, L, Haras, M, Sandu, A, Spircu, T“…Results: Concerning d FIM, there have not been objectified significant differences between the two lots (p=0.2453) but regarding key, focused on neuro–motor rehabilitative outcomes, functional/analytical parameters: KE (p=0.0007) and days until the first time recovery of the ability to walk between parallel bars (WPB–p=0.0000)–highly significant differences in favor of Cerebrolysin lot resulted. …”
Publicado 2009
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3411“…Ct-pros is expressed in single cells in neural and non-neural ectoderm, while Ct-msi and Ct-neuroD are localized to differentiating neural cells in the brain and ventral nerve cord. …”
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3412por Ikoma, Katsunori“…Yukio Mano, MD, PhD (1943–2004) Associate Editor, Journal of NeuroEngineering and Rehabilitation…”
Publicado 2005
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3413por Pelalak, Rasool, Nakhjiri, Ali Taghvaie, Marjani, Azam, Rezakazemi, Mashallah, Shirazian, Saeed“…Four membership functions (MFs) in each input parameter are insufficient to predict the gas fraction in the 3D bubble column reactor. However, by adding two membership functions, all features of gas fraction in the 3D reactor can be captured by the machine learning algorithm. …”
Publicado 2021
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3414por Iemolo, Francesco, Sanzaro, Enzo, Duro, Giovanni, Giordano, Antonello, Paciaroni, Maurizio“…BACKGROUND: Ischemic injury triggers inflammatory cascades and changes in the protein synthesis, neurotransmitters and neuro-hormones in the brain parenchyma that may further amplify the tissue damage. …”
Publicado 2016
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3415“…The network connection density under both defense behaviors was significantly higher than the period before and after defensive behavior occurred, indicating that there was a high synchronization of neural activity during the defense process. CONCLUSIONS: The dPAG nuclei of mice have different coding features between flight and freezing behaviors; during strong looming stimulation, fast neuro‐instinctive decision making is required while encountering weak sweeping stimulation, and computable planning late behavior is predicted in the early stage. …”
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3416por Le Bihan, Denis“…</p> <p style="text-align:justify"><strong>Biography and position</strong>: Denis Le Bihan holds an M.D. (Neurosurgery and Radiology) and a Ph.D in Physics (Nuclear and Elementary Particles). …”
Publicado 2016
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3417por Hu, Ze-Lan, Shi, Ming, Huang, Ying, Zheng, Min-Hua, Pei, Zhe, Chen, Jia-Yin, Han, Hua, Ding, Yu-Qiang“…CONCLUSIONS: Our data indicate that Rbpj-mediated canonical Notch signaling inhibits DRG neuronal differentiation, possibly by regulating NeuroD1 expression, and is required for DRG gliogenesis in vivo.…”
Publicado 2011
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3418por Vargas, Nancy, Álvarez-Cubela, Silvia, Giraldo, Jaime A., Nieto, Margarita, Fort, Nicholas M., Cechin, Sirlene, García, Enrique, Espino-Grosso, Pedro, Fraker, Christopher A., Ricordi, Camillo, Inverardi, Luca, Pastori, Ricardo L., Domínguez-Bendala, Juan“…Alongside Pdx1 and Beta2/NeuroD, the transcription factor MafA has been shown to be instrumental in the maintenance of the beta cell phenotype. …”
Publicado 2011
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3419por Xie, Jianwei, Chen, Pengchen, Xie, Hongteng, Sun, Yuqin, Huang, Zhen, Wei, Ran, Miao, Zhengqiang, Wang, Qingshui, Zhang, Shu-Dong, Wong, Koon Ho, Lin, Yao, Huang, Changming, Kwok, Hang Fai“…Knockdown of NeuroD1 enhanced the sensitivity to irinotecan of GNEC cell lines. …”
Publicado 2020
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3420por Gerace, Dario, Martiniello-Wilks, Rosetta, Habib, Rosaline, Ren, Binhai, Nassif, Najah Therese, O'Brien, Bronwyn Anne, Simpson, Ann Margaret“…Ex vivo expanded MSCs were transduced with the HMD lentiviral vector (MOI = 10) to express furin-cleavable human insulin (INS-FUR) and murine NeuroD1 and Pdx1. This was followed by the characterization of pancreatic transdifferentiation via reverse transcriptase polymerase chain reaction (RT-PCR) and static and glucose-stimulated insulin secretion (GSIS). …”
Publicado 2019
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