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  1. 3841
    “…Mechanistically, βFaar promote the synthesis and secretion of insulin by upregulating islet-specific genes Ins2, NeuroD1, and Creb1 through sponging miR-138-5p. In addition, using quantitative mass spectrometry, we identify TRAF3IP2 and SMURF1 as interacting proteins that are specifically associated with βFaar. …”
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    The long non-coding RNA βFaar regulates islet β-cell function and survival during obesity in mice
  2. 3842
    “…This study was aimed to demonstrate the in vivo neuroprotective effect of NAC against aluminum (Al(3+))-induced neuro-degeneration in rats (a model for AD). Twenty- five (25) adult male Wistar rats used for this study were divided into 5 groups: Group A = Control, B = Aluminum chloride (200 mg/kg), C = 1000 mg/kg of NAC + Aluminum chloride (200 mg/kg), D = 1000 mg/kg of NAC, E = Aluminum chloride (200 mg/kg) was orally administered daily for 3 weeks and discontinued for one week. …”
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    Histomorphological evaluations on the frontal cortex extrapyramidal cell layer following administration of N-Acetyl cysteine in aluminum induced neurodegeneration rat model
  3. 3843
    “…The recent molecular stratification of gliomas by the World Health Organisation in 2021 is expected to improve outcomes for patients in neuro-oncology through the development of treatments targeted to specific tumour types. …”
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    Considerations for modelling diffuse high-grade gliomas and developing clinically relevant therapies
  4. 3844
    “…Tissue morphology, abundance of chromogranin A, gut hormones, α-defensin, mucin 2, Na(+)/glucose co-transporter 1 (SGLT1) and transcription factors, Hes1, HATH1, NeuroD1, and Ngn3, were determined. In obese patients, the total number of enteroendocrine cells (EEC) and EECs containing gut hormones were significantly reduced in the stomach and duodenum, compared to lean, and returned to normality post-LSG. …”
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    Deregulation of transcription factors controlling intestinal epithelial cell differentiation; a predisposing factor for reduced enteroendocrine cell number in morbidly obese individuals
  5. 3845
    “…Moreover, mRNA and protein expression of the key regulators in glucose sensing and insulin secretion (Insulin, GLUT2, NeuroD1, and INSR) were downregulated in Cpne3-silenced cells. …”
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    Copine 3 “CPNE3” is a novel regulator for insulin secretion and glucose uptake in pancreatic β-cells
  6. 3846
    “…An attenuation of HPC neuroprotection as well as a reduction in the expression of neurogenesis markers, including p57 and NeuroD1, was observed in preconditioned mice lacking NCX1 or NCX3. …”
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    Preconditioning in hypoxic-ischemic neonate mice triggers Na(+)-Ca(2+) exchanger-dependent neurogenesis
  7. 3847
    “…Then, berberine promoted C17.2 cell to differentiate into neurons and the differentiation mechanism involved the activation of WNT/β-catenin pathway as well as the upregulation of expression levels of pro-neural factors Achaete-Scute Complex-Like 1 (ASCL1), Neurogenin 1 (NeuroG1), Neuronal Differentiation 2 (NeuroD2) and Doublecortin (DCX). …”
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    Berberine Protects C17.2 Neural Stem Cells From Oxidative Damage Followed by Inducing Neuronal Differentiation
  8. 3848
    “…Additionally, the mRNA and protein expression of the proneural genes Ngn1 and NeuroD, which are crucial for neurite outgrowth, were decreased after RF-EMF exposure. …”
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    Exposure to 1800 MHz radiofrequency radiation impairs neurite outgrowth of embryonic neural stem cells
  9. 3849
    “…Using our approach, we could consolidate the role of BDNF and implicate new genes (AnxA8, NeuroD2) in serotonergic functioning. Despite its explorative nature, the analysis can be seen as a gene prioritization approach to reduce the number of genes potentially connected to 5-HT(1A)R functioning and guide future in vitro studies.…”
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    Topologically Guided Prioritization of Candidate Gene Transcripts Coexpressed with the 5-HT(1A) Receptor by Combining In Vivo PET and Allen Human Brain Atlas Data
  10. 3850
    “…Cytochrome P450 (CYP) is its metabolic enzyme, and the drug’s biofunction results from its neuro-protective effect in animal and cell models. …”
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    Duloxetine-Induced Neural Cell Death and Promoted Neurite Outgrowth in N2a Cells
  11. 3851
    “…The proteomic analysis of left ventricular (LV) sample was determined using two-dimensional (2-D) gel electrophoresis and MALDI-TOF-MS. The serum levels of the systemic inflammatory and neuro-hormonal factors were assayed using radioimmunoassay kits. …”
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    Ameliorated stress related proteins are associated with improved cardiac function by sarcoplasmic reticulum calcium ATPase gene transfer in heart failure
  12. 3852
    “…Defect-doors&radiators&windows (air-currents) induce respiratory-diseases, defect-illumination causes accidents (neuro-orthopaedic diseases: commotio-cerebri,etc.). …”
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    On social psychiatry: Psychopathology of German justice on example of resident houses (RH)
  13. 3853
    “…VCP was measured using the NeuroTracker(™) CORE (NT) 3-Dimensional (3-D) software program (15 training sessions) over a 15-day period. …”
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    The impact of nutrition on visual cognitive performance in the nutrition, vision, and cognition in sport study
  14. 3854
    “…CONCLUSIONS: The present study demonstrates that PAMs of NMDA receptor have pharmacotherapeutic potentials to reverse down-regulated NMDA receptor signaling, neuro-socio-cognitive abnormalities and decreased neurogenesis in hippocampal cKO mice. …”
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    NMDA receptor agonists reverse impaired psychomotor and cognitive functions associated with hippocampal Hbegf-deficiency in mice
  15. 3855
    “…These studies demonstrate that neuro-inflammation following viral infection increases expression of activating FcγRs on M1-polarized microglia. …”
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    Modulation of Microglial Cell Fcγ Receptor Expression Following Viral Brain Infection
  16. 3856
    “…Interestingly, the VPA-induced TERT overexpression resulted to sequential upregulations of glutamatergic markers such as Ngn2 and NeuroD1, and inter-synaptic markers such as PSD-95, α-CaMKII, vGluT1 and synaptophysin. …”
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    Valproic Acid Induces Telomerase Reverse Transcriptase Expression during Cortical Development
  17. 3857
    “…The pancreatic and duodenal homeobox factor-1 (Pdx1) and Neurogenic differentiation 1 (NeuroD1) expressions were decreased in the islet of F2-HF rats at the age of week 12. …”
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    Maternal high-fat diet impairs glucose metabolism, β-cell function and proliferation in the second generation of offspring rats
  18. 3858
    “…At the biochemical level, changes in Willin/FRMD6 expression inversely affected the activity of the extracellular signal-regulated kinases (ERK) pathway and downstream transcriptional factor NeuroD1, which seems to prime SH-SY5Y cells for retinoic acid (RA)-induced neuronal differentiation.…”
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    Willin/FRMD6 Influences Mechanical Phenotype and Neuronal Differentiation in Mammalian Cells by Regulating ERK1/2 Activity
  19. 3859
    “…In 2019, an international panel of pediatric neuro-oncology experts convened to advance therapy for ETMR. …”
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    ETMR-08. INTERNATIONAL CONSENSUS PROTOCOL FOR EMBRYONAL TUMOR WITH MULTILAYER ROSETTES
  20. 3860
    “…Knockdown of dachb was associated with a significant downregulation of the β‐cell specific marker gene, insa, and the somatostatin cell marker, sst2, as well as regulators of pancreas development, ptf1a, neuroD, pax6a and nkx6.1, and the cell cycle gene, insm1a. …”
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    Investigating the role of dachshund b in the development of the pancreatic islet in zebrafish
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