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261por Andersson, Ulrika, Wibom, Carl, Cederquist, Kristina, Aradottir, Steina, Borg, Åke, Armstrong, Georgina N., Shete, Sanjay, Lau, Ching C., Bainbridge, Matthew N., Claus, Elizabeth B., Barnholtz-Sloan, Jill, Lai, Rose, Il'yasova, Dora, Houlston, Richard S., Schildkraut, Joellen, Bernstein, Jonine L., Olson, Sara H., Jenkins, Robert B., Lachance, Daniel H., Wrensch, Margaret, Davis, Faith G., Merrell, Ryan, Johansen, Christoffer, Sadetzki, Siegal, Bondy, Melissa L., Melin, Beatrice S., Adatto, Phyllis, Morice, Fabian, Payen, Sam, McQuinn, Lacey, McGaha, Rebecca, Guerra, Sandra, Paith, Leslie, Roth, Katherine, Zeng, Dong, Zhang, Hui, Yung, Alfred, Aldape, Kenneth, Gilbert, Mark, Weinberger, Jeffrey, Colman, Howard, Conrad, Charles, de Groot, John, Forman, Arthur, Groves, Morris, Levin, Victor, Loghin, Monica, Puduvalli, Vinay, Sawaya, Raymond, Heimberger, Amy, Lang, Frederick, Levine, Nicholas, Tolentino, Lori, Saunders, Kate, Thach, Thu-Trang, Iacono, Donna Dello, Sloan, Andrew, Gerson, Stanton, Selman, Warren, Bambakidis, Nicholas, Hart, David, Miller, Jonathan, Hoffer, Alan, Cohen, Mark, Rogers, Lisa, Nock, Charles J, Wolinsky, Yingli, Devine, Karen, Fulop, Jordonna, Barrett, Wendi, Shimmel, Kristen, Ostrom, Quinn, Barnett, Gene, Rosenfeld, Steven, Vogelbaum, Michael, Weil, Robert, Ahluwalia, Manmeet, Peereboom, David, Staugaitis, Susan, Schilero, Cathy, Brewer, Cathy, Smolenski, Kathy, McGraw, Mary, Naska, Theresa, Rosenfeld, Steven, Ram, Zvi, Blumenthal, Deborah T., Bokstein, Felix, Umansky, Felix, Zaaroor, Menashe, Cohen, Avi, Tzuk-Shina, Tzeela, Voldby, Bo, Laursen, René, Andersen, Claus, Brennum, Jannick, Henriksen, Matilde Bille, Marzouk, Maya, Davis, Mary Elizabeth, Boland, Eamon, Smith, Marcel, Eze, Ogechukwu, Way, Mahalia, Lada, Pat, Miedzianowski, Nancy, Frechette, Michelle, Paleologos, Nina, Byström, Gudrun, Svedberg, Eva, Huggert, Sara, Kimdal, Mikael, Sandström, Monica, Brännström, Nikolina, Hayat, Amina, Tihan, Tarik, Zheng, Shichun, Berger, Mitchel, Butowski, Nicholas, Chang, Susan, Clarke, Jennifer, Prados, Michael, Rice, Terri, Sison, Jeannette, Kivett, Valerie, Duo, Xiaoqin, Hansen, Helen, Hsuang, George, Lamela, Rosito, Ramos, Christian, Patoka, Joe, Wagenman, Katherine, Zhou, Mi, Klein, Adam, McGee, Nora, Pfefferle, Jon, Wilson, Callie, Morris, Pagan, Hughes, Mary, Britt-Williams, Marlin, Foft, Jessica, Madsen, Julia, Polony, Csaba, McCarthy, Bridget, Zahora, Candice, Villano, John, Engelhard, Herbert, Borg, Ake, Chanock, Stephen K, Collins, Peter, Elston, Robert, Kleihues, Paul, Kruchko, Carol, Petersen, Gloria, Plon, Sharon, Thompson, Patricia, Johansen, C., Sadetzki, S., Melin, B., Bondy, Melissa L., Lau, Ching C., Scheurer, Michael E., Armstrong, Georgina N., Liu, Yanhong, Shete, Sanjay, Yu, Robert K., Aldape, Kenneth D., Gilbert, Mark R., Weinberg, Jeffrey, Houlston, Richard S., Hosking, Fay J., Robertson, Lindsay, Papaemmanuil, Elli, Claus, Elizabeth B., Claus, Elizabeth B., Barnholtz-Sloan, Jill, Sloan, Andrew E., Barnett, Gene, Devine, Karen, Wolinsky, Yingli, Lai, Rose, McKean-Cowdin, Roberta, Il'yasova, Dora, Schildkraut, Joellen, Sadetzki, Siegal, Yechezkel, Galit Hirsh, Bruchim, Revital Bar-Sade, Aslanov, Lili, Sadetzki, Siegal, Johansen, Christoffer, Kosteljanetz, Michael, Broholm, Helle, Bernstein, Jonine L., Olson, Sara H., Schubert, Erica, DeAngelis, Lisa, Jenkins, Robert B., Yang, Ping, Rynearson, Amanda, Andersson, Ulrika, Wibom, Carl, Henriksson, Roger, Melin, Beatrice S., Cederquist, Kristina, Aradottir, Steina, Borg, Åke, Merrell, Ryan, Lada, Patricia, Wrensch, Margaret, Wiencke, John, Wiemels, Joe, McCoy, Lucie, McCarthy, Bridget J., Davis, Faith G.Enlace del recurso
Publicado 2014
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262por Hao, Xiujuan, Huang, Yan, Qiu, Ming, Yin, Chunlin, Ren, Huiming, Gan, Hongjie, Li, Huijun, Zhou, Yaxia, Xia, Jiazhi, Li, Wenting, Guo, Lijuan, Angres, Isaac A.“…Clinical investigations using immunoassays to measure SAM, SAH and the methylation index (MI) in normal and diseased samples indicated that (1) the SAM level is age and gender dependent; (2) the SAM level is associated with the severity of liver diseases, inflammatory reactions and other diseases; and (3) the methylation index (MI) is significantly reduced in many diseases and may serve as a screening biomarker to identify potentially unfavorable health conditions. …”
Publicado 2016
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263“…PRINCIPAL FINDINGS: Here we report that the developmental phenotype of the drb235 triple mutant plant is the result of deregulated miRNA biogenesis in the shoot apical meristem (SAM) region. …”
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264por Feng, Jianbo, Ren, Xing, Fu, Haijuan, Li, Di, Chen, Xiguang, Zu, Xuyu, Liu, Qing, Wu, Minghua“…Thus, the LRRC4/SAM68/circCD44/miR-326/miR-330-5p/SMAD6 signaling axis could be a potential target for GBM treatment.…”
Publicado 2021
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265por Rodrigues, Vandasue L., Dolde, Ulla, Sun, Bin, Blaakmeer, Anko, Straub, Daniel, Eguen, Tenai, Botterweg-Paredes, Esther, Hong, Shinyoung, Graeff, Moritz, Li, Man-Wah, Gendron, Joshua M., Wenkel, Stephan“…Detailed analysis of the genetic interaction among CO, JMJ14, miP1a/b, and TPL revealed a potential role for CO as a repressor of flowering in the shoot apical meristem (SAM). …”
Publicado 2021
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266por ZHENG, GUORONG, XIONG, YIMIN, XU, WEITIAN, WANG, YAN, CHEN, FANG, WANG, ZHIGANG, YAN, ZHI“…Finally, quantitative PCR was used to validate the candidate biomarkers for early gastric cancer in the test samples (35 cancer and 33 normal samples). Using the SAM algorithm, 14 differential miRNAs were selected as candidate biomarkers. …”
Publicado 2014
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267“…RESULTS: We compared miFDR with the BH approach, the Storey approach and SAM on both simulated datasets and public DNA microarray datasets. …”
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268por Im, Ji Hye, Kim, Tae Hoon, Lee, Kyue-Yim, Gwak, Ho-Shin, Lin, Weiwei, Park, Jong Bae, Kim, Jong Heon, Yoo, Byong Chul, Park, Seong-Min, Kwon, Ji-Woong, Shin, Sang Hoon, Yoo, Heon“…Using SAM comparisons between LM and BM samples, we identified 30 upregulated and 6 downregulated LM miRNAs. …”
Publicado 2021
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270por Hu, Shengqing, Liao, Yunfei, Zheng, Juan, Gou, Luoning, Regmi, Anita, Zafar, Mohammad Ishraq, Chen, Lulu“…Based on the gene microarray data GSE82208 and microRNA dataset GSE62054, the differentially expressed genes (DEGs) and microRNAs (DEMs) were obtained using R and SAM software. The common DEMs from R and SAM were fed to three different bioinformatic tools, TargetScan, miRDB, and miRTarBase, respectively, to predict their biological targets. …”
Publicado 2019
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271por Lykova, Maria, Panchenko, Iuliana, Schneider-Ramelow, Martin, Suga, Tadatomo, Mu, Fengwen, Buschbeck, RoyEnlace del recurso
Publicado 2023
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272“…The recent observation that the inhibition of MAT2A and MAT2B expression by miRNAs leads to a rise of endogenous SAM and strong inhibition of cancer cell growth could open new perspectives to the treatment of HCC.…”
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274por Minow, Mark A. A., Coneva, Viktoriya, Lesy, Victoria, Misyura, Max, Colasanti, Joseph“…First, the phloem companion-cell specific SUCROSE-PROTON SYMPORTER2 (SUC2) promoter was used to drive expression of an inverted repeat to target the FD gene, an exclusively SAM-localized floral regulator. Second, the SUC2 promoter was used to express an artificial microRNA (aMiR) designed to target a synthetic CLAVATA3 (CLV3) transgene in SAM stem cells. …”
Publicado 2022
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275
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276“…In addition, the integration of this SAM-modified microfabricated thin film RE enabled the rapid detection (<30 min) of miRNA (let-7a). …”
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277por Laurent, L, Dolgashev, V A, Nantista, C D, Tantawi, S G, Aicheler, M, Heikkinen, S T, Wuensch, W, Higashi, Y“…The cavity is a one port hemispherical cavity that operates in the TE013-like mode at 11.424 GHz. The test samples are mounted onto the endcap of the cavity. …”
Publicado 2010
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278por Rudolf, Eva Esther, Hüther, Patrick, Forné, Ignasi, Georgii, Elisabeth, Han, Yongtao, Hell, Rüdiger, Wirtz, Markus, Imhof, Axel, Becker, Claude, Durner, Jörg, Lindermayr, Christian“…This SAM accumulation triggered a substantial increase in the methylation index (MI = [SAM]/[S-adenosylhomocysteine]), indicating the transmethylation activity and histone methylation status in higher eukaryotes. …”
Publicado 2021
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279“…Shoot apical meristems (SAM) are tissues that function as a site of continuous organogenesis, which indicates that a small pool of pluripotent stem cells replenishes into lateral organs. …”
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