Mostrando 481 - 500 Resultados de 23,460 Para Buscar 'SPDIF~', tiempo de consulta: 3.25s Limitar resultados
  1. 481
    “…These events are largely controlled by tissue-specific transcription factors. These transcription factors must function within the context of chromatin to activate or repress target genes. …”
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  2. 482
    “…Thus, pendolmycin was as potent as teleocidin B and phorbol ester tumor promoters in modification of cell membrane functions, while having the simplest structure among them.…”
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  3. 483
  4. 484
    “…Particularly, increasing evidence is emerging that DNA methylation and histone modifications play an important role in gene regulation and are involved in alteration of the phenotype and function of vascular cells in response to environmental stresses. …”
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  5. 485
  6. 486
    “…Post translational modifications such as methylation or acetylation on histones have been well characterized, and their role in enhancing or inhibiting specific gene expression was clearly elucidated. …”
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  7. 487
    “…Therefore, natural and mutant glycosidases are excellent tools for modifications of flavonoid glycosides.…”
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  8. 488
  9. 489
    “…The involvement of chromatin modifications in the regulation of the core circadian clock genes is also discussed.…”
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  10. 490
    por Mucha, Artur
    Publicado 2012
    “…Improved methods for the formation of the phosphinic peptide backbone, including stereoselective and multicomponent reactions, are presented. Parallel modifications leading to the structurally diversified substituents are also described. …”
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  11. 491
    “…The synthetic investigation of biologically active natural compounds serves two main purposes: (i) the total synthesis of alkaloids and their analogues; (ii) modification of the structures for producing more selective, more effective, or less toxic derivatives. …”
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  12. 492
    “…Higher plants can produce a wide variety of anthocyanin molecules through modification of the six common anthocyanin aglycons that they present. …”
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  13. 493
  14. 494
    “…While the role of impurities has been studied extensively in various materials systems, the inherent complexity of eutectic crystallization in the presence of trace, often metallic impurities (‘eutectic modification’) remains poorly understood. In particular, the origins behind the drastic microstructural changes observed upon modification are elusive. …”
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  15. 495
    por Jezek, Meagan, Green, Erin M.
    Publicado 2019
    “…The structure of chromatin at telomeres and within adjacent subtelomeres has been implicated in telomere maintenance pathways in model systems and humans. Specific post-translational modifications of histones, including methylation, acetylation, and ubiquitination, have been shown to be necessary for maintaining a chromatin environment that promotes telomere integrity. …”
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  16. 496
  17. 497
  18. 498
    “…Recently however, it has been determined that implications in epigenetic modification seem to expand into various neurodegenerative disease mechanisms. …”
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  19. 499
  20. 500
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