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Mostrando 521 - 540 Resultados de 23,460 Para Buscar 'SPDIF~', tiempo de consulta: 1.98s Limitar resultados
  1. 521
    “…This study involves a slight modification on the tube used, with a 20 cm-long weight of 20 g. …”
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    Modification of the Marmarou model in developing countries
  2. 522
    “…Furthermore, the fusion of effector enzymes with nuclease-deficient Cas9 (dCas9) in clustered regularly interspaced short palindromic repeats (CRISPR) associated protein 9 (Cas9) system equips a potent tool for locus-specific erasure or establishment of DNA methylation as well as histone modifications and, therefore, transcriptional regulation of specific genes. …”
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    Targeting Epigenetic Modifications in Uveal Melanoma
  3. 523
    “…The main mechanism of proteasome activity regulation is provided by modulation of their composition and post-translational modifications (PTMs). Moreover, diverse PTMs of proteins are known to participate in the loading of specific elements into extracellular vesicles. …”
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    Post-Translational Modifications of Extracellular Proteasome
  4. 524
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    Modification of Collagen Properties with Ferulic Acid
  5. 525
    por Barbon, Alessandro, Magri, Chiara
    Publicado 2020
    “…However, the importance of RNA modifications has attracted little attention until now in this field. …”
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    RNA Editing and Modifications in Mood Disorders
  6. 526
    “…Density modification uses expectations about features of a map such as a flat solvent and expected distributions of density in the region of the macromolecule to improve individual Fourier terms representing the map. …”
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    Density modification of cryo-EM maps
  7. 527
    “…Developing chemical and biological tools to detect specific modifications in the genome or transcriptome has greatly facilitated their study. …”
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    Mapping the epigenetic modifications of DNA and RNA
  8. 528
    “…Enhancers can be identified by their unique chromatin signature, including transcription factor binding and the enrichment of specific histone post-translational modifications, histone variants, and chromatin-associated cofactors. …”
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    Establishment and function of chromatin modification at enhancers
  9. 529
    “…Epigenetic modifications including histone modifications and DNA and RNA modifications are involved in multiple biological processes and human diseases. …”
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    The Roles of Base Modifications in Kidney Cancer
  10. 530
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    Colored ligature: Trivial but innovative modification
  11. 531
    “…Herein, we summarized modification of traditional nucleoside framework (sugar + base), traizole nucleosides, nucleoside analogues assembled by other drugs, macromolecule-modified nucleosides, and their bioactivity rules. 2′-“Ara”-substituted by –F or –CN group, and 3′-“ara” substituted by acetylenyl group can greatly influence their anti-tumor activities. …”
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    Advance of structural modification of nucleosides scaffold
  12. 532
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    The Impact of Epigenetic Modifications in Myeloid Malignancies
  13. 533
    “…Although the involvement of these protein modifications and sugars is well-studied, there is still a long road ahead to profoundly comprehend their nature, significance, importance for plant development and the interplay with stress responses. …”
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    Sweet Modifications Modulate Plant Development
  14. 534
    “…Herein, we summarize the association between SUMOylation modification events and four types of cellular death processes: apoptosis, autophagy, senescence and pyroptosis. …”
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    SUMOylation modification-mediated cell death
  15. 535
    “…A novel, two-parameter modification of a Drude model, based on fractional time derivatives, is presented. …”
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    Fractional Derivative Modification of Drude Model
  16. 536
    por Chen, Li, Kashina, Anna
    Publicado 2021
    “…Post-translational modifications (PTM) involve enzyme-mediated covalent addition of functional groups to proteins during or after synthesis. …”
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    Post-translational Modifications of the Protein Termini
  17. 537
    “…There are many scientific articles on the hydrothermal modification of wood, and many aspects of hydrothermal modification are summarized in review papers in this field. …”
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    Hydrothermal Modification of Wood: A Review
  18. 538
    por Ramesh, Vaidhiswaran, Krishnan, J
    Publicado 2021
    “…Multisite modification is a basic way of conferring functionality to proteins and a key component of post-translational modification networks. …”
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    Symmetry breaking meets multisite modification
  19. 539
    “…A central phenomenon in tumor malignancy is metabolic dysfunctionality; it reprograms metabolic homeostasis in tumor and stromal cells thus affecting metabolic modifications on specific proteins. These posttranslational modifications include glycosylation and palmitoylation, which usually alter the protein localization, stability, and function. …”
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    Metabolic Modifications, Inflammation, and Cancer Immunotherapy
  20. 540
    por Sugimoto, Chiho, Robison, A.J.
    Publicado 2021
    “…Zhang and colleagues provide new understanding of memory formation by uncovering the lysine acetyltransferase SRC3 as the key driver of the novel posttranslational modification of calmodulin (CaM) acetylation, which regulates CaM's activity and subsequent activation of CaMKII. …”
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    Calmodulin acetylation: A modification to remember
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