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  1. 801
    “…OBJECTIVES: To evaluate tissue modifications in chromoblastomycosis carriers under itraconazole treatment. …”
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    Chromoblastomycosis: tissue modifications during itraconazole treatment
  2. 802
    “…In this report, we reviewed the current knowledge of APP modifications and trafficking as well as their role in APP processing. …”
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    Modifications and Trafficking of APP in the Pathogenesis of Alzheimer’s Disease
  3. 803
    “…CONCLUSION: In most patients referred to the cardiologist after being screened at an outpatient anaesthesiology clinic, echocardiography is performed for ruling out specific conditions and to be sure that no further improvement can be made in the patient’s health. …”
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    The preoperative cardiology consultation: indications and risk modification
  4. 804
    “…SUMOylation, as a post-translational modification, plays essential roles in various biological functions including cell growth, migration, cellular responses to stress and tumorigenesis. …”
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    Protein SUMOylation modification and its associations with disease
  5. 805
    “…Post-translational modifications are one of the factors that affect the properties of the tubulin polymer. …”
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    Tubulin Post-Translational Modifications and Microtubule Dynamics
  6. 806
    “…Some kind of a surface treatment is often necessary to achieve properties suitable for specific applications. There are multiple methods of surface treatment, each with their own pros and cons, such as plasma and laser treatment, UV lamp modification, etching, grafting, metallization, ion sputtering and others. …”
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    Surface Modification of Polymer Substrates for Biomedical Applications
  7. 807
    por Heiss, Matthias, Kellner, Stefanie
    Publicado 2016
    “…To understand the biological role of these modified nucleosides, nucleic acid scientists need tools to specifically label, detect and enrich modified nucleic acids. …”
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    Detection of nucleic acid modifications by chemical reagents
  8. 808
    por Helm, Mark
    Publicado 2017
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    Editorial: RNA modifications – what to read first?
  9. 809
    “…The addition of novel side chains at the 5-position of uracil is an effective means to increase chemical diversity of aptamers and hence the success rate for discovery of high-affinity ligands to protein targets. Such modifications also increase nuclease resistance, which is useful in a range of applications, especially for therapeutics. …”
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    Pharmacokinetic Properties of DNA Aptamers with Base Modifications
  10. 810
    “…The rapid development of genome modification technology has provided many great benefits in diverse areas of research and industry. …”
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    Genome Modification Technologies and Their Applications in Avian Species
  11. 811
    “…Herein we discuss the mechanism of epigenetic modification and its implication in CRC development, progression even metastasis by gut microbiota induction.…”
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    Gut microbiota, epigenetic modification and colorectal cancer
  12. 812
    “…Secondly, the least absolute shrinkage and selection operator is used to reduce multicollinearity without the modification of explanatory variables. Thirdly, proportions of SC types and age are considered to construct individual diagnostic models and classify the training set and the test set for reflecting the characteristics of the entire dataset. …”
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    Modification of the Integrated Sasang Constitutional Diagnostic Model
  13. 813
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    Modification of Bacterial Cellulose Biofilms with Xylan Polyelectrolytes
  14. 814
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    Modification of Epigenetic Histone Acetylation in Hepatocellular Carcinoma
  15. 815
    “…The relevance of this kind of nanorod in a complex measurement setting can be further improved by suitable surface modification and functionalization procedures, so that customized nanostructures for a specific application become available. …”
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    Applications, Surface Modification and Functionalization of Nickel Nanorods
  16. 816
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    Chemical modification of group IV graphene analogs
  17. 817
    “…SUMOylation is a reversible post-translational modification which has emerged as a crucial molecular regulatory mechanism, involved in the regulation of DNA damage repair, immune responses, carcinogenesis, cell cycle progression and apoptosis. …”
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    The post-translational modification, SUMOylation, and cancer (Review)
  18. 818
    “…Here we show the computer-assisted design of sulfonyl acrylate reagents for the modification of a single lysine residue on native protein sequences. …”
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    Chemo- and Regioselective Lysine Modification on Native Proteins
  19. 819
    por Kim, Youngeun, Jho, Eek-hoon
    Publicado 2018
    “…Interestingly, non-degradative ubiquitin modifications are also known to play important roles in the regulation of Hippo signaling. …”
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    Regulation of the Hippo signaling pathway by ubiquitin modification
  20. 820
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    Correction: Role of novel histone modifications in cancer
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