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  1. 821
    por Pan, Tao
    Publicado 2018
    “…Transfer RNA (tRNA) is present at tens of millions of transcripts in a human cell and is the most abundant RNA in moles among all cellular RNAs. tRNA is also the most extensively modified RNA with, on an average, 13 modifications per molecule. The primary function of tRNA as the adaptor of amino acids and the genetic code in protein synthesis is well known. tRNA modifications play multi-faceted roles in decoding and other cellular processes. …”
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    Modifications and functional genomics of human transfer RNA
  2. 822
    “…In order to improve the applicability for vaccine delivery, researchers have carried out various chemical modifications of chitosan. This review summarizes a variety of modification methods and applications of chitosan and its derivatives in the field of vaccine delivery.…”
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    Chemical Modification of Chitosan for Efficient Vaccine Delivery
  3. 823
    “…Many of the chemical modifications that decorate DNA and histones are adducts derived from intermediates of cellular metabolic pathways. …”
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    Metabolic regulation of chromatin modifications and gene expression
  4. 824
    “…This reaction has been frequently used in carbohydrate chemistry for the modification of sugar hydroxy groups. Modification at the anomeric position, leading mainly to anomeric esters or glycosides, is of particular importance in the glycosciences. …”
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    Anomeric modification of carbohydrates using the Mitsunobu reaction
  5. 825
    “…[Image: see text] Honeybee silk proteins can be produced at high levels in recombinant systems, fabricated into materials, and are tolerant of amino acid modifications: properties that make them exciting templates for designing new functional materials. …”
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    Modification of Honeybee Silk by the Addition of Antimicrobial Agents
  6. 826
    “…We aim to review current and developing surface modifications with a view towards antibacterial orthopaedic implants for clinical applications.…”
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    Antibacterial surface modification of titanium implants in orthopaedics
  7. 827
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    Surface Modifications of Nanoparticles for Stability in Biological Fluids
  8. 828
    “…This review summarizes the chemical modifications to render synthetic porphyrins water-soluble, with a focus on the work disclosed since 2000. …”
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    Modifications of Porphyrins and Hydroporphyrins for Their Solubilization in Aqueous Media
  9. 829
    “…This special issue, collecting total synthesis and structural modification of six different type of bioactive MNPs, is expected to inspire and attract more research effects invested into MNP research.…”
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    Synthesis and Structural Modification of Marine Natural Products
  10. 830
    “…The layer charge reduced and the CEC value increased after fluorosilicate modification, which means the modified sericite is a promising matrix for clay-polymer nanocomposites.…”
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    The modification and characterization of thermal-treated sericite by fluorosilicate
  11. 831
    “…This review summarizes the different types and the structural modification of these new BACE1 inhibitors.…”
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    Development and Structural Modification of BACE1 Inhibitors
  12. 832
    “…Post-translational modifications (PTMs), including phosphorylation, acetylation, ubiquitination, SUMOylation, etc., of proteins can modulate protein properties such as intracellular distribution, activity, stability, aggregation, and interactions. …”
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    Roles of Post-translational Modifications in Spinocerebellar Ataxias
  13. 833
    por Eelen, Paul
    Publicado 2018
    “…This presentation was given as the introduction to the L.A.P.P. seminar day held October 27, 1980, which was themed: Behaviour modification. The lecture was published as: Eelen, P. (1980). …”
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    Behaviour Therapy and Behaviour Modification Background and Development
  14. 834
    “…Appropriate surface modification of IONPs can conquer these barriers with improved physicochemical properties. …”
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    Surface Modification of Magnetic Iron Oxide Nanoparticles
  15. 835
    por Ifuku, Shinsuke
    Publicado 2014
    “…Acidic conditions are the key factor to facilitate mechanical fibrillation. Surface modification is an effective way to change the surface property and to endow nanofiber surface with other properties. …”
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    Chitin and Chitosan Nanofibers: Preparation and Chemical Modifications
  16. 836
    “…As part of our continuing studies on the structural modification of oxyresveratrol, a library of twenty-six compounds was prepared via O-alkylation, aromatic halogenation, and electrophilic aromatic substitution. …”
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    Oxyresveratrol: Structural Modification and Evaluation of Biological Activities
  17. 837
    por Oh, HyungSeon, Hu, Zhe
    Publicado 2018
    “…Rank-1 modifications applied k-times (k > 1) often are performed to achieve a rank-k modification. …”
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    Multiple-rank modification of symmetric eigenvalue problem
  18. 838
    “…Notably, there is an increased proportion and activation state of specific monocyte subsets in systemic blood circulation. …”
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    Monocyte Subsets in Atherosclerosis and Modification with Exercise in Humans
  19. 839
    “…An experimental approach called LAIC-seq was developed to characterize modification levels on a transcriptome-wide scale. In this method, the modified and unmodified molecules are separated using antibodies specific for a given RNA modification (e.g., m(6)A). …”
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    RNA Modification Level Estimation with pulseR
  20. 840
    por Bottecchia, Cecilia, Noël, Timothy
    Publicado 2018
    “…Owing to mild reaction conditions (i.e., room temperature, use of visible light) and high functional‐group tolerance, photoredox catalysis could represent an ideal strategy for chemoselective biomolecule modification. Indeed, a recent trend in photoredox catalysis is its application to the development of novel methodologies for amino acid modification. …”
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    Photocatalytic Modification of Amino Acids, Peptides, and Proteins
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