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  1. 941
    “…In this study, we utilized sets of histone modification data, which are precisely distributed at either gene bodies or promoters to evaluate the annotation of the Zea mays genome. …”
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    Leveraging histone modifications to improve genome annotations
  2. 942
    “…The specific recognition of DNA modifications by the transcriptional protein machinery is thought to be a potential mechanism for epigenetic‐driven gene regulation, and many modified DNA‐specific binding proteins have been uncovered. …”
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    Proteome‐Wide Profiling of Readers for DNA Modification
  3. 943
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    Genetic Modification of Sodalis Species by DNA Transduction
  4. 944
    por Shigi, Naoki
    Publicado 2021
    “…Modulating sulfur modification controls the translation efficiency of specific groups of genes, allowing organisms to adapt to specific environments. …”
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    Biosynthesis and Degradation of Sulfur Modifications in tRNAs
  5. 945
    “…In addition, their regulation through post-translational modifications (PTMs) constitutes a major mechanism to shape their action positively or negatively. …”
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    Regulation of Viral Restriction by Post-Translational Modifications
  6. 946
    por Zhang, Nan, Zuo, Yuxin, Peng, Yu, Zuo, Lielian
    Publicado 2021
    “…N6-Methyladenosine (m6A) modification is a dynamic and reversible methylation modification at the N6-position of adenosine. …”
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    Function of N6-Methyladenosine Modification in Tumors
  7. 947
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    Editorial: Neuroprotection and Disease Modification in Parkinson’s Disease
  8. 948
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    Modification of Glass/Polyester Laminates with Flame Retardants
  9. 949
    “…This review introduces the compounds used for vitrification solutions (VSs), their properties indicating a modification of different plant vitrification solutions, their modifications in the compounds, and/or their concentration. …”
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    Vitrification Solutions for Plant Cryopreservation: Modification and Properties
  10. 950
    “…Post-translational modifications of histone proteins regulate a long cascade of downstream cellular activities, including transcription and replication. …”
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    Histone modifications in neurodifferentiation of embryonic stem cells
  11. 951
    “…We will also discuss the functionalization of BC to yield nanocomposites and the surface modification of BC by plasma and irradiation-based methods to fabricate materials with improved functionalities such as bactericidal capabilities.…”
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    Surface Modification of Bacterial Cellulose for Biomedical Applications
  12. 952
    por Servatius, Phil, Kazmaier, Uli
    Publicado 2022
    “…Activation and cyclization give direct access to cyclopeptides related to naturally occurring histone deacetylase (HDAC) inhibitors Cyl-1 and Cyl-2. Late stage modifications on the unsaturated amino acid side chain allow the introduction of functionalities which might coordinate to metal ions in the active center of metalloproteins, such as histone deacetylases.…”
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    Synthesis and late stage modifications of Cyl derivatives
  13. 953
    “…In this review, we describe genetic modifications to OVs that improve their ability to kill tumor cells directly, to dismantle the tumor microenvironment, or to alter tumor cell signaling and enhance anti-tumor immunity. …”
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    Genetic Modifications That Expand Oncolytic Virus Potency
  14. 954
    “…Aside from current use of DNA-targeting CRISPR-Cas9, the more recently discovered CRISPR-Cas13 has been explored as a means of editing due to its RNA-targeting capabilities. Specifically, there has been a recent interest in identifying and functionally characterizing biochemical RNA modifications, which has spurred a new field of research known as “epitranscriptomics”. …”
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    The Basis and Promise of Programmable RNA Editing and Modification
  15. 955
    por Leuenberger, Muriel
    Publicado 2022
    “…From this, I conclude that an analysis of MMTs based on a dual-basis, process view of authenticity is warranted, which implies that the influence of MMTs on authenticity crucially depends on the specifics of how memory modification would eventually work. …”
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    Memory Modification and Authenticity: A Narrative Approach
  16. 956
    “…In a homogeneous population of 161 patients, with a median age of 75 years, we found that 28.7% were frail according to the G8 test, while the estimated survival at 10 years was 2.25% based on the Charlson test. The therapeutic modification increased to 21% after frailty analysis, and the radiotherapy prescribed was 5.8 times more likely to be modified in frail patients. …”
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    The Impact of Frailty Screening on Radiation Treatment Modification
  17. 957
    por Blake, Lynsay I., Cann, Martin J.
    Publicado 2022
    “…Further, we describe recent studies on new techniques to isolate this problematic post-translational modification.…”
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    Carbon Dioxide and the Carbamate Post-Translational Modification
  18. 958
    “…Khan et al examine in detail ways in which the Montreal Cognitive Assessment (MoCA) has been modified for different languages and cultures and produce a systematic guide for future modifications. However, questions arise regarding the availability of the MoCA. …”
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    Cultural modification of neuropsychiatric assessment: complexities to consider
  19. 959
    “…Both ubiquitination and SUMOylation are dynamic post-translational modifications that regulate thousands of target proteins to control virtually every cellular process. …”
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    Insights in Post-Translational Modifications: Ubiquitin and SUMO
  20. 960
    “…Here, we will summarize recent advances in the regulatory and functional role of RNA modifications in these cellular functions, emphasizing the context-specific roles of RNA modifications in mammalian systems. …”
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    Roles of RNA Modifications in Diverse Cellular Functions
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