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  1. 1141
    “…Accumulating evidence has revealed the role of aberrant gene expression in CVD caused by dysregulated RNA modification. In this review, we focus on nine common RNA modifications: N(6)-methyladenosine (m(6)A), N(1)-methyladenosine (m(1)A), 5-methylcytosine (m(5)C), N(7)-methylguanosine (m(7)G), N(4)-acetylcytosine (ac(4)C), pseudouridine (Ψ), uridylation, adenosine-to-inosine (A-to-I) RNA editing, and modifications of U34 on tRNA wobble. …”
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    RNA modification in cardiovascular disease: implications for therapeutic interventions
  2. 1142
    “…The selenization of natural products refers to the chemical modification method of artificially introducing selenium atoms into natural products to interact with the functional groups in the target molecule to form selenides. …”
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    Selenium Modification of Natural Products and Its Research Progress
  3. 1143
    “…We also developed eRNA prediction models using joint gene expressions, DNA methylation, and histone modification. These models achieved impressive performance with an AUC value of approximately 0.95 for intra-cell prediction and 0.9 for cross-cell prediction. …”
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    Predicting active enhancers with DNA methylation and histone modification
  4. 1144
    “…In this study, we report a skeletal modification strategy for conversion of polar cyclic pyrrolidines into nonpolar linear dienes through a N-atom removal and deconstruction process. …”
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    Synthesis of dienes from pyrrolidines using skeletal modification
  5. 1145
    “…In neuroscience, there is a pressing need to isolate and characterize the epigenomes of specific CNS cell types in health and disease. In this study, we developed an in vivo tagging mouse model (Camk2a-NuTRAP) for paired isolation of neuronal DNA and RNA without cell sorting and then used this model to assess epigenomic regulation, DNA modifications in particular, of gene expression between neurons and glia. …”
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    Differential usage of DNA modifications in neurons, astrocytes, and microglia
  6. 1146
    “…RNA epitranscriptomic modifications, particularly the reversible modification methylation, have been observed throughout the RNA cycle. …”
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    Insights into the regulatory role of RNA methylation modifications in glioma
  7. 1147
    “…This study proposes a novel blockchain architecture called Unlichain that provides data-modification features within public blockchain architecture. …”
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    Data Modifications in Blockchain Architecture for Big-Data Processing
  8. 1148
    por Lian, Jie, Liu, Wenwu, Hu, Qin, Zhang, Xiaohua
    Publicado 2023
    “…However, the role of succinylation modification in cell metabolism after stroke and its regulation are not well understood. …”
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    Succinylation modification: a potential therapeutic target in stroke
  9. 1149
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    Modification of the existing maximum residue level for propamocarb in honey
  10. 1150
    “…When a plasmid containing restriction–modification (R–M) genes enters a naïve host, unmodified host DNA can be destroyed by restriction endonuclease. …”
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    Transcription regulation of the EcoRV restriction–modification system
  11. 1151
    por Helm, Mark
    Publicado 2006
    “…There are about 100 different base modifications known, which may perform a plethora of functions. …”
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    Post-transcriptional nucleotide modification and alternative folding of RNA
  12. 1152
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    The envelopes of amphibian oocytes: physiological modifications in Bufo arenarum
  13. 1153
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    Thermal modification of chrysotile asbestos: evidence for decreased cytotoxicity.
  14. 1154
    por Peabody, David S
    Publicado 2003
    “…MS2) have characteristics that make them suitable scaffolds to which a variety of substances could be chemically attached in definite geometric patterns. To provide for specific chemical modification of MS2's outer surface, cysteine residues were substituted for several amino acids present on the surface of the wild-type virus particle. …”
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    A Viral Platform for Chemical Modification and Multivalent Display
  15. 1155
    “…In this study, we have investigated the kinetics and thermodynamics of sequence-specific modification of DNA with deoxyribooligonucleotide linked to Co(II)-tetracarboxyphthalocyanine (PtcCo(II)) in the presence of H(2)O(2).…”
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    Kinetic Study of DNA Modification by Phthalocyanine Derivative of the Oligonucleotide
  16. 1156
    “…While multiple studies have demonstrated that modification of atherosclerotic cardiovascular risk factors (CVRFs) significantly reduces morbidity and mortality rates, clinical control of CVDs and CVRFs remains poor. …”
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    A New Paradigm of Cardiovascular Risk Factor Modification
  17. 1157
    por Christakos, S., Sinha, D., Dao, T. L.
    Publicado 1976
    “…The relationship between neonatal modification of endocrine functions and mammary tumourigenesis is discussed.…”
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    Neonatal modification of endocrine functions and mammary carcinogenesis in the rat.
  18. 1158
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    Organization of chromatin and histone modifications at a transcription site
  19. 1159
    “…With computational simulations, we suggest that with this slow oscillation-induced plasticity, a recurrent network converges on a more specific state, compared to that with spike timing-dependent plasticity alone.…”
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    Active Hippocampal Networks Undergo Spontaneous Synaptic Modification
  20. 1160
    por Smith, Theobald
    Publicado 1897
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    A MODIFICATION OF THE METHOD FOR DETERMINING THE PRODUCTION OF INDOL BY BACTERIA
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