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  1. 1241
    “…In addition, they pave the way for difficult experiments such as tissue-specific allele switching and functional analysis in post-mitotic or polyploid cells. …”
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    Accelerated homologous recombination and subsequent genome modification in Drosophila
  2. 1242
    “…BACKGROUND: Cognitive bias modification (CBM) protocols have been developed to help establish the causal role of biased cognitive processing in maintaining psychopathology and have demonstrated therapeutic benefits in a range of disorders. …”
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    Cognitive Bias Modification (CBM) of obsessive compulsive beliefs
  3. 1243
    “…Since then, there have been numerous modifications to the selection procedures. This review discusses the use of modified bases as a means of enhancing serum stability and producing effective therapeutic tools, as well as functionalising these nucleic acids to be used as potential diagnostic agents.…”
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    Aptamers as Theranostic Agents: Modifications, Serum Stability and Functionalisation
  4. 1244
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    Age-Related Modifications to the Magnitude and Periodicity of Neuromuscular Noise
  5. 1245
    “…However, it remains challenging to link chromatin modifications to eRNA transcription. Herein, we develop a logistic regression model to unravel the relationship between chromatin modifications and eRNA synthesis. …”
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    Predicting enhancer transcription and activity from chromatin modifications
  6. 1246
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    Semiconductor-based DNA sequencing of histone modification states
  7. 1247
    “…Post-translational modifications of tau and its interaction with several proteins play an important regulatory role in the physiology of tau. …”
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    Tau Protein Modifications and Interactions: Their Role in Function and Dysfunction
  8. 1248
    por Gao, Chenxi, Xiao, Gutian, Hu, Jing
    Publicado 2014
    “…Increasing evidence suggests that post-translational modifications (PTMs) of Wnt pathway components are essential for the activation of the Wnt/β-catenin pathway. …”
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    Regulation of Wnt/β-catenin signaling by posttranslational modifications
  9. 1249
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    Modification in Laryngeal mask airway CTrach tube design
  10. 1250
    “…This paper firstly summarizes the two factors causing the organic membrane fouling, including molecular weight (MW) and hydrophilicity/hydrophobicity of NOM, and then presents a brief introduction of the methods which can prevent membrane fouling such as pretreatment of the feed water (e.g., coagulation, adsorption, and pre-oxidation) and membrane hydrophilic modification (e.g., plasma modification, irradiation grafting modification, surface coating modification, blend modification, etc.). …”
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    Pretreatment and Membrane Hydrophilic Modification to Reduce Membrane Fouling
  11. 1251
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    Genetic Modification of the Effects of Exercise Behavior on Mental Health
  12. 1252
    por Sayarlioglu, Hayriye
    Publicado 2013
    “…Although the decrease in blood pressure may be limited with these measures, lifestyle modifications should be continued.…”
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    Rational approaches to the treatment of hypertension: modification of lifestyle measures
  13. 1253
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    Modest Effects of Lipid Modifications on the Structure of Caveolin-3
  14. 1254
    “…The ‘tubulin-code’ hypothesis proposes that different tubulin genes or posttranslational modifications (PTMs), which mainly confer variation in the carboxy-terminal tail (CTT), result in unique interactions with microtubule-associated proteins for specific cellular functions. …”
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    Regulation of microtubule motors by tubulin isotypes and posttranslational modifications
  15. 1255
    “…Stable alterations in gene function in the immune system have been reported in several studies of CFS. Epigenetic modifications have been implicated in long-term effects on gene function, however, to our knowledge, genome-wide epigenetic modifications associated with CFS have not been explored. …”
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    DNA Methylation Modifications Associated with Chronic Fatigue Syndrome
  16. 1256
    “…Activation of immune complexes is associated with post-translational modifications (PTMs) of proteins, such as phosphorylation, glycosylation, or ubiquitination. …”
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    Identification of Post-translational Modifications of Plant Protein Complexes
  17. 1257
    “…The purpose of this study is to describe technique modifications and report surgical outcomes following KDs at a high-volume Limb Salvage Center. …”
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    Through Knee Amputation: Technique Modifications and Surgical Outcomes
  18. 1258
    “…[Image: see text] Identification of histone post-translational modifications (PTMs) is challenging for proteomics search engines. …”
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    Evaluation of Proteomic Search Engines for the Analysis of Histone Modifications
  19. 1259
    “…It has been shown that both DNA methylation and histone modifications are involved in DNA damage response to various types of stresses. …”
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    Epigenetic chromatin modifications in barley after mutagenic treatment
  20. 1260
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    Galacto‐oligosaccharides attenuate renal injury with microbiota modification
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