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  1. 1281
    por Low, Jin-Yih, Nicholson, Helen D.
    Publicado 2015
    “…Here, we summarize the current knowledge of the role of epigenetic modification in regulating the expression of these caveolae related genes and how this relates to changes in cellular physiology and in health and disease.…”
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    Epigenetic modifications of caveolae associated proteins in health and disease
  2. 1282
    “…Several of these modification sites are conserved from yeast to human. …”
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    Posttranslational Modifications and Clearing of α-Synuclein Aggregates in Yeast
  3. 1283
    “…Objective To study the presentation and treatment in two infants who presented with refractory Sandifer syndrome (SS). Study Design We retrospectively reviewed the cases of two infants who presented to our outpatient clinic with SS who were refractory to conventional treatment. …”
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    Treatment of Sandifer Syndrome with an Amino-Acid–Based Formula
  4. 1284
    “…Using a combination of bioinformatics, biochemical analysis, and cell-based assays, we identify here specific histone modifications as facilitators of chromosome breakage and translocations. …”
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    Histone modifications predispose genome regions to breakage and translocation
  5. 1285
    “…Protein localization and dynamics can now be visualized in living cells using the fluorescent protein fusion technique, but it is still difficult to selectively detect molecules with a specific function. As a posttranslational protein modification is often associated with a specific function, marking specifically modified protein molecules in living cells is a way to track an important fraction of protein. …”
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    Visualizing posttranslational and epigenetic modifications of endogenous proteins in vivo
  6. 1286
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    Microsurgical Technique Modifications: Practical Tips for Improving Precision
  7. 1287
    “…We describe an optimized system for the easy, effective, and precise modification of the Escherichia coli genome. Genome changes are introduced first through the integration of a 1.3 kbp Landing Pad consisting of a gene conferring resistance to tetracycline (tetA) or the ability to metabolize the sugar galactose (galK). …”
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    An Integrated System for Precise Genome Modification in Escherichia coli
  8. 1288
    “…Its theme was Beyond the Genome, with talks focused on the various influences of posttranslational modifications in malignant transformation and the spread of cancer. …”
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    Origins of cancer symposium 2015: posttranslational modifications and cancer
  9. 1289
    “…Here we propose a scenario for coupling between the electric field of light and spins via optical modification of the exchange interaction, one of the strongest quantum effects with strength of 10(3) Tesla. …”
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    Ultrafast optical modification of exchange interactions in iron oxides
  10. 1290
    por Levi, Sonia, Rovida, Ermanna
    Publicado 2015
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    Neuroferritinopathy: From ferritin structure modification to pathogenetic mechanism
  11. 1291
    “…Here, crucial proteins which mediate synaptic transmission can undergo posttranslational modifications with either pre- or postsynaptic origin. …”
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    Nitric Oxide-Mediated Posttranslational Modifications: Impacts at the Synapse
  12. 1292
    por Baldwin, Graham S., Sims, Ioulia
    Publicado 2015
    “…To investigate the effect of tyrosine modification on ferric ion binding, the changes in absorbance of gastrin(17), gastrin(17)SO(4) and gastrin(17)PO(4) on addition of Fe(3+) ions were monitored. …”
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    Tyrosine modification increases the affinity of gastrin for ferric ions
  13. 1293
    “…Interestingly, maize centromeres also have lower levels of the heterochromatin histone modification mark H3K27me2 relative to pericentromeric regions. …”
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    Gene Expression and Chromatin Modifications Associated with Maize Centromeres
  14. 1294
    “…The causative role of these modifications in inducing protein misfolding and aggregation was determined by inducing carbonyl stress in young mice, which recapitulated the increased protein aggregation observed in old mice. …”
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    Role of Carbonyl Modifications on Aging-Associated Protein Aggregation
  15. 1295
    “…Post-translational modification (PTM) is recognized as a major process accounting for protein structural variation, functional diversity, and the dynamics and complexity of the proteome. …”
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    Protein Phosphorylation and Redox Modification in Stomatal Guard Cells
  16. 1296
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    Prosthodontic Management of Xerostomic Patient: A Technical Modification
  17. 1297
    “…Oligonucleotide aptamers have comparable affinity and specificity to targets with monoclonal antibodies whilst they have minimal immunogenicity, high production, low cost and high stability, thus are promising inhibitors to rival antibodies for disease therapy. …”
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    Molecular Selection, Modification and Development of Therapeutic Oligonucleotide Aptamers
  18. 1298
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    Modification of tooth development by heat shock protein 60
  19. 1299
    “…The pathophysiology and epidemiologic links between ED and risk factors for cardiovascular disease (CVD) are well-established. Lifestyle modifications such as smoking cessation, weight reduction, dietary modification, physical activity, and psychological stress reduction have been increasingly recognized as foundational to the prevention and treatment of ED. …”
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    Can lifestyle modification affect men’s erectile function?
  20. 1300
    “…Chemical formation of dehydroalanine has been widely used for the post-translational modification of proteins and peptides, however methods to incorporate multiple dehydroalanine residues into a single peptide have not been defined. …”
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    Chemical generation and modification of peptides containing multiple dehydroalanines
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