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1321por Ma, Lijia, Zhao, Boxuan, Chen, Kai, Thomas, Amber, Tuteja, Jigyasa H., He, Xin, He, Chuan, White, Kevin P.“…Here we analyze m(6)A mRNA modifications in lymphoblastoid cell lines (LCLs) from human, chimpanzee and rhesus, and we identify patterns of m(6)A evolution among species. …”
Publicado 2017
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1322por Fahrenkrog, Birthe“…The mechanism by which chromosomes restructure during apoptosis is still poorly understood, but it is becoming increasingly clear that altered epigenetic histone modifications are fundamental parameters that influence the chromatin state and the nuclear rearrangements within apoptotic cells. …”
Publicado 2015
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1323
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1324“…Nano-hydroxyapatite and its modification, hydroxyapatite with the excess of phosphorus (P-HAP) and hydroxyapatite with the carbon ions built into the structure (C-HAP), were prepared by the wet method. …”
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1325“…Here, we describe an efficient workflow for the synthesis of RNA with a single mP modification in diastereomerically pure form. While the automated assembly of mP-modified RNA is straightforward, its deprotection under basic conditions is challenging; a carefully optimized step-by-step procedure is provided. …”
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1326por Fleisher, Adam S., Donohue, Michael, Chen, Kewei, Brewer, James B., Aisen, Paul S., the Alzheimer’s Disease Neuroimaging InitiativeEnlace del recurso
Publicado 2009
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1327“…The hydrophobic amine-salt modification resulting in high spacing of layered or exfoliation of individual clay platelets is the most important factor for gaining significant improvements of properties. …”
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1328“…Here, we review some of the technological advances in this rapidly developing field, identify the conceptual challenges and discuss approaches that are needed to rigorously test the biological function of specific RNA modifications.…”
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1329por Mahé, Elise A., Madigou, Thierry, Sérandour, Aurélien A., Bizot, Maud, Avner, Stéphane, Chalmel, Frédéric, Palierne, Gaëlle, Métivier, Raphaël, Salbert, Gilles“…However, the functional relationship between cytosine modifications and the chromatin architecture of enhancers remains elusive. …”
Publicado 2017
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1330por Yu, Mingming, Feng, Bin, Xie, Wang, Fang, Lin, Li, Hong, Liu, Liqi, Ren, Musu, Sun, Jinliang, Zhang, Jiabao, Hu, Hefeng“…The results indicated that the modification would help the prepolymer improve its molecular mobility. …”
Publicado 2015
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1331“…The present FePt NPs synthesized using oleic acid and oleylamine as the stabilizers under identical conditions were achieved with a simple method. The surface modification of FePt NPs by using mercaptoacetic acid (thiol) as a phase transfer reagent through ligand exchange turned the NPs hydrophilic, and the FePt NPs were water-dispersible. …”
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1332“…They show a highly conserved secondary and tertiary structure and the highest density of post-transcriptional modifications among all RNAs. These modifications concentrate in two hotspots—the anticodon loop and the tRNA core region, where the D- and T-loop interact with each other, stabilizing the overall structure of the molecule. …”
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1333
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1334por Clark, William P., Steinberg, Simon, Dronskowski, Richard, McCammon, Catherine, Kupenko, Ilya, Bykov, Maxim, Dubrovinsky, Leonid, Akselrud, Lev G., Schwarz, Ulrich, Niewa, Rainer“…At pressures between 10 and 45 GPa, significant magnetic hyperfine splitting indicated compound formation after annealing at 1300 K. …”
Publicado 2017
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1336“…The current study aimed to compare the effectiveness of three different types of training programmes (cognitive bias modification-attention, CBM-A; cognitive bias modification-interpretation, CBM-I; attention and interpretation modification, AIM) administered via smart-phones by using a control condition (CC). …”
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1337por Ni, Shuaijian, Yao, Houzong, Wang, Lili, Lu, Jun, Jiang, Feng, Lu, Aiping, Zhang, Ge“…In this review, we will discuss methods to conquer these challenges and highlight recent developments of chemical modifications and technological advances that may enable early aptamers to be translated into clinical therapeutics.…”
Publicado 2017
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1338
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1339por Liang, Yanping, Dearnaley, William J., Varano, A. Cameron, Winton, Carly E., Gilmore, Brian L., Alden, Nick A., Sheng, Zhi, Kelly, Deborah F.“…We refer to this site as a modification “hotspot.” Ubiquitin adducts in the hotspot region proved to be biochemically reversible. …”
Publicado 2017
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1340