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1361
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1362por Hu, Jingchu, Wang, Wenqing, Homan, Philipp, Wang, Penggui, Zheng, Xifu, Schiller, Daniela“…Here, we provide a first systematic investigation of reminder duration effects on threat memory modification in humans. Reminder duration was parametrically varied across 155 participants in a three-day protocol. …”
Publicado 2018
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1363“…It includes modifications of DNA nucleotides, nucleosomal remodeling, and post-translational modifications (PTMs). …”
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1364“…The article reveals patterns of changes in the parameters of oxidative modification of proteins for different periods of the inflammatory process in periodontal tissues during periodontitis. …”
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1365“…In addition, PPAR functions are also regulated by various Post-translational modifications (PTMs). These PTMs include phosphorylation, SUMOylation, ubiquitination, acetylation, and O-GlcNAcylation, which are found at numerous modification sites. …”
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1366“…However, in addition to phosphorylation events, tau undergoes a number of diverse posttranslational modifications (PTMs) which appear to be controlled by complex crosstalk. …”
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1367“…N6-methyladenosine (m6A) epitranscriptional modification has recently gained much attention. Through the development of m6A sequencing, the molecular mechanism and importance of m6A have been revealed. m6A is the most abundant internal modification in higher eukaryotic mRNAs, which plays crucial roles in mRNA metabolism and multiple biological processes. …”
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1368“…This points towards the importance of certain lifestyle modifications that can help prevent and treat this disorder. …”
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1369“…Vector control strategies based on population modification of Anopheline mosquitoes may have a significant role in the malaria eradication agenda. …”
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1370por Morena, Francesco, Argentati, Chiara, Bazzucchi, Martina, Emiliani, Carla, Martino, Sabata“…In fact, depending on the type of modification, RNA molecules enter into a specific program exerting the role of the player or/and the target in biological and pathological processes. …”
Publicado 2018
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1371por Hughes, Christopher D., Isaac, Kathryn V., Hwang, Paul F., Ganske, Ingrid, Proctor, Mark R., Meara, John G.“…In this study, we describe a modification of the Melbourne method of total calvarial remodeling for correcting scaphocephaly. …”
Publicado 2018
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1372“…Thereby, post-translational modifications (PTMs) of viral and cellular proteins gain increasingly attention as modifying enzymes regulate virtually every step of the viral replication cycle. …”
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1373por Massi, Alessandro, Bortolini, Olga, Ragno, Daniele, Bernardi, Tatiana, Sacchetti, Gianni, Tacchini, Massimo, De Risi, Carmela“…However, low bioavailability, poor aqueous solubility as well as rapid body clearance, fast metabolism and enzymatic degradation hamper the use of quercetin as therapeutic agent, so intense research efforts have been focused on the modification of the quercetin scaffold to obtain analogs with potentially improved properties for clinical applications. …”
Publicado 2017
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1374“…The investigation of post-translational modifications (PTMs) plays an important role for the study of type 2 diabetes. …”
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1375“…Accumulating evidence showed that epigenetic modifications could in turn alter metabolism in tumors. …”
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1376por Wood, Ian C.“…Exactly how epigenetic modifications contribute to specific aspects of Alzheimer’s disease is the focus of many researcher groups across the world. …”
Publicado 2018
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1377por Zaccaria, Sabrina, van Gaal, Ronald C., Riool, Martijn, Zaat, Sebastian A. J., Dankers, Patricia Y. W.“…Biomaterials based on non‐active polymers functionalized with antimicrobial agents by covalent modification or mixing are currently regarded as high potential solutions to prevent biomaterial associated infections that are major causes of biomedical device failure. …”
Publicado 2018
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1378por Mashhour, Ahmed, Zhigalov, Konstantin, Szczechowicz, Marcin, Mkalaluh, Sabreen, Easo, Jerry, Eichstaedt, Harald, Borodin, Dmitry, Ennker, Jürgen, Weymann, AlexanderEnlace del recurso
Publicado 2018
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1379por Yang, Fan“…Protein post-translational modifications (PTMs), such as phosphorylation, acetylation, methylation, and ubiquitination, have been shown to control protein activity, regulate protein stability, promote protein interactions and alter protein subcellular localization, leading to the modulation of crucial signaling pathways and affected cellular processes. …”
Publicado 2018
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1380por Ibañez, Sergio J., Garcia-Rubio, Javier, Gómez, Miguel-Ángel, Gonzalez-Espinosa, Sergio“…Rule modifications in basketball are used to develop the sport, and FIBA changes the basketball regulations periodically and constantly in search of a more attractive game. …”
Publicado 2018
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