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1381“…Recently published work by our group and others, regarding environmentally induced transgenerational effects, have identified an array of mechanisms, with a particular focus on histone modifications, that shed some light on the underlying epigenetic processes driving long-term generational effects.…”
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1382“…Indeed, in the past two decades, random screening involving chemical modification, post-SELEX chemical modification, and rational design methods have been advanced, and combining and integrating these methods may produce a new class of functional nucleic acids. …”
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1383
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1384por Hollenstein, MarcelEnlace del recurso
Publicado 2012
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1385por Shaughnessy, Kevin H.“…Synthetic modification of nucleoside structures provides access to molecules of interest as pharmaceuticals, biochemical probes, and models to study diseases. …”
Publicado 2015
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1386por Yang, Yuh-Shyong, Wang, Chen-Chu, Chen, Bo-Han, Hou, You-Hua, Hung, Kuo-Sheng, Mao, Yi-Chih“…Protein tyrosine sulfation (PTS) is a common post-translational modification that was first reported in the literature fifty years ago. …”
Publicado 2015
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1387por Satulu, Veronica, Ionita, Maria Daniela, Vizireanu, Sorin, Mitu, Bogdana, Dinescu, Gheorghe“…We discuss several plasma techniques for surface fluorination: deposition of fluorocarbon thin films either by magnetron sputtering of polytetrafluoroethylene targets, or by plasma-assisted chemical vapor deposition using tetrafluoroethane as a precursor, and modification of carbon nanowalls by plasma treatment in a sulphur hexafluoride environment. …”
Publicado 2016
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1388por Chi, Haotian, Wang, Xiaoli, Shao, Yue, Qin, Ying, Deng, Zixin, Wang, Lianrong, Chen, Shi“…This review provides an update on recent advances in engineering, modification and application of synthetic microbial chassis, with particular emphasis on the value of learning about chassis as a way to better understand life and improve applications.…”
Publicado 2018
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1390
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1391por Tomikawa, Chie“…More than 90 different modified nucleosides have been identified in tRNA. Among the tRNA modifications, the 7-methylguanosine (m(7)G) modification is found widely in eubacteria, eukaryotes, and a few archaea. …”
Publicado 2018
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1392“…On the other hand, recent advances suggest that metabolic pathways could directly signal into chromatin modifications and impact on specific gene programs. The key metabolites acetyl-CoA or S-adenosyl-methionine (SAM) are examples of important metabolic hubs which play in addition a role in chromatin acetylation and methylation. …”
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1393por Ačkar, Đurđica, Babić, Jurislav, Jozinović, Antun, Miličević, Borislav, Jokić, Stela, Miličević, Radoslav, Rajič, Marija, Šubarić, Drago“…Researchers are continually trying to improve its properties by different modification procedures and expand its application. What is mostly applied in this view are their chemical modifications, among which organic acids have recently drawn the greatest attention, particularly with respect to the application of starch in the food industry. …”
Publicado 2015
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1394
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1395“…Histone modifications are associated with alternative splicing. …”
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1396“…We aim to provide a modification to reduce the postoperative “step” defect. …”
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1397por Krupnik, Valery“…I propose to apply Bayesian framework to psychotherapy integration and discuss a possibility of using it as a universal strategy called Strategic Modification of Priors (SMOP). I illustrate SMOP's application with a synopsis of a clinical case.…”
Publicado 2019
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1398“…This work may promote research on the atomic‐scale structural modification of 2D materials toward functional applications.…”
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1399por Perchey, Renaud T., Tonini, Laure, Tosolini, Marie, Fournié, Jean-Jacques, Lopez, Frédéric, Besson, Arnaud, Pont, Frédéric“…Discovery of protein modification sites relies on protein digestion by proteases and mass spectrometry (MS) identification of the modified peptides. …”
Publicado 2019
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1400por Heo, Kyung-Sun“…Although underlying mechanisms have been suggested for how SENPs participate in breast cancer tumorigenesis, such as through regulation of target protein transactivation, cancer cell survival, cell cycle, or other post-translational modification-related machinery recruitment, the effect of SENP isoform-specific inhibitors on the progression of breast cancer have not been well evaluated. …”
Publicado 2019
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