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  1. 1401
    “…This previously unrecognized structural modification impacts host-pathogen interaction and has implications for vaccine design.…”
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    Discovery of glycerol phosphate modification on streptococcal rhamnose polysaccharides
  2. 1402
    “…Among a number of mRNA modifications, N(6)-methyladenosine (m(6)A) modification is the most common type in eukaryotes and nuclear-replicating viruses. m(6)A has a significant role in numerous cancer types, including leukemia, brain tumors, liver cancer, breast cancer and lung cancer. …”
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    Detection of N(6)-methyladenosine modification residues (Review)
  3. 1403
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    Epigenetic Modifications in Placenta are Associated with the Child's Sensitization to Allergens
  4. 1404
    “…Additionally, the modification of soluble (13.32%) and insoluble dietary fiber (8.79%) ratio through pressure cooking was nonsignificant while roasting showed significant results, that is, 53.91% increase in soluble dietary fiber and 8.79% decrease in insoluble dietary fiber. …”
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    Modification of barley dietary fiber through thermal treatments
  5. 1405
    por Rahhal, Raneen, Seto, Edward
    Publicado 2019
    “…Histone modifications and RNA splicing, two seemingly unrelated gene regulatory processes, greatly increase proteome diversity and profoundly influence normal as well as pathological eukaryotic cellular functions. …”
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    Emerging roles of histone modifications and HDACs in RNA splicing
  6. 1406
    “…The present review introduces the natural hydrogels, which are often used for cartilage tissue engineering with respect to synthesis, modification and application methods. THE TRANSLATIONAL POTENTIAL OF THIS ARTICLE: This review introduces the natural hydrogels that are often used in cartilage tissue engineering with respect to synthesis, modification and application methods. …”
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    Natural hydrogels for cartilage regeneration: Modification, preparation and application
  7. 1407
    “…The result of analysis revealed that only a subset of RNA modification regulatory proteins are overexpressed in >75% of melanoma patient cases as compared to normal skin. …”
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    Dissecting the role of RNA modification regulatory proteins in melanoma
  8. 1408
    por Liu, Qi, Gregory, Richard I
    Publicado 2019
    “…Here, we developed RNAmod (https://bioinformatics.sc.cn/RNAmod), an interactive, one-stop, web-based platform for the automated analysis, annotation, and visualization of mRNA modifications in 21 species. RNAmod provides intuitive interfaces to show outputs including the distribution of RNA modifications, modification coverage for different gene features, functional annotation of modified mRNAs, and comparisons between different groups or specific gene sets. …”
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    RNAmod: an integrated system for the annotation of mRNA modifications
  9. 1409
    “…Consequently, MMP activity is tightly regulated through a combination of epigenetic, transcriptional, and post-transcriptional control of gene expression, proteolytic activation, post-translational modifications (PTMs), and extracellular inhibition. In addition, MMPs, their substrates and ECM binding partners are frequently modified by PTMs, which suggests an important role of PTMs in modulating the pleiotropic activities of these proteases. …”
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    Post-Translational Modification-Dependent Activity of Matrix Metalloproteinases
  10. 1410
    “…All in all, the PEG modification of TxID was improved in stability, resistance to enzymatic degradation, and may prolong the half-life in vivo, which may pave the way for the future application in smoking cessation and drug rehabilitation, as well as small cell lung cancer.…”
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    DSPE-PEG Modification of α-Conotoxin TxID
  11. 1411
    “…A set of sulfabetaine copolymers containing about 1 mol % (based on the repeat units) of reactive benzophenone methacrylate was prepared, spin-coated onto solid substrates, and photo-cured. …”
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    Surface Modification by Polyzwitterions of the Sulfabetaine-Type, and Their Resistance to Biofouling
  12. 1412
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    Unsubstituted Bambusurils: Post-Macrocyclization Modification of Versatile Intermediates
  13. 1413
    por Copland, M.
    Publicado 2019
    “…PURPOSE OF REVIEW: For patients with chronic phase chronic myeloid leukemia (CP-CML), there is an increasing focus on personalization of therapy with dose modifications of tyrosine kinase inhibitors (TKIs) to reduce side effects and maintain efficacy. …”
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    Is There a Role for Dose Modification of TKI Therapy in CML?
  14. 1414
    “…BACKGROUND: Perturbed posttranslational modification (PTM) landscapes commonly cause pathological phenotypes. …”
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    Systematic analysis of the intersection of disease mutations with protein modifications
  15. 1415
    por Banks, C.J., Andersen, J.L.
    Publicado 2019
    “…In this review, we address emerging mechanisms of SOD1 regulation by post-translational modifications, many of which begin to shed light on how the various functions of SOD1 are regulated within the cell.…”
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    Mechanisms of SOD1 regulation by post-translational modifications
  16. 1416
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    Editorial: Organ Modification for Edible Parts of Horticultural Crops
  17. 1417
    “…Variety of their applications is caused by a number of practically important properties, e.g., biocompatibility and biodegradability, non-toxicity, and mechanical durability. Modification of these polymers with different additives allows improving their properties and extending future applications. …”
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    Modification of Oligo- and Polylactides With Macrocyclic Fragments: Synthesis and Properties
  18. 1418
    por Hamam, Hussein J., Palaniyar, Nades
    Publicado 2019
    “…In fact, emerging evidence reveal that the post translational modifications (PTMs) of histones in neutrophils have a critical role in regulating neutrophil death. …”
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    Post-Translational Modifications in NETosis and NETs-Mediated Diseases
  19. 1419
    por Liu, Yanqing, Tavana, Omid, Gu, Wei
    Publicado 2019
    “…Among the multiple layers of mechanisms controlling p53 function, posttranslational modifications (PTMs) represent an efficient and precise way. …”
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    p53 modifications: exquisite decorations of the powerful guardian
  20. 1420
    “…Significantly larger modification of soma size, but not neurofilament labeling, was observed at the critical period peak when dark exposure preceded monocular deprivation. …”
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    Modification of Peak Plasticity Induced by Brief Dark Exposure
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