Allosteric modulation of AURKA kinase activity by a small-molecule inhibitor of its protein-protein interaction with TPX2

por Janeček, Matej, Rossmann, Maxim, Sharma, Pooja, Emery, Amy, Huggins, David J., Stockwell, Simon R., Stokes, Jamie E., Tan, Yaw S., Almeida, Estrella Guarino, Hardwick, Bryn, Narvaez, Ana J., Hyvönen, Marko, Spring, David R., McKenzie, Grahame J., Venkitaraman, Ashok R.
Publicado 2016

Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin–sensitizing effects of metformin

por Fullerton, Morgan D., Galic, Sandra, Marcinko, Katarina, Sikkema, Sarah, Pulinilkunnil, Thomas, Chen, Zhi–Ping, O’Neill, Hayley M., Ford, Rebecca J., Palanivel, Rengasamy, O’Brien, Matthew, Hardie, D. Grahame, Macaulay, S. Lance, Schertzer, Jonathan D., Dyck, Jason R. B., van Denderen, Bryce J., Kemp, Bruce E., Steinberg, Gregory R.
Publicado 2013

AMP‐activated protein kinase: a cellular energy sensor that comes in 12 flavours

por Ross, Fiona A., MacKintosh, Carol, Hardie, D. Grahame
Publicado 2016

Role of the Polymerase ϵ sub-unit DPB2 in DNA replication, cell cycle regulation and DNA damage response in Arabidopsis

por Pedroza-Garcia, José Antonio, Domenichini, Séverine, Mazubert, Christelle, Bourge, Mickael, White, Charles, Hudik, Elodie, Bounon, Rémi, Tariq, Zakia, Delannoy, Etienne, del Olmo, Ivan, Piñeiro, Manuel, Jarillo, Jose Antonio, Bergounioux, Catherine, Benhamed, Moussa, Raynaud, Cécile
Publicado 2016

Herboxidiene triggers splicing repression and abiotic stress responses in plants

por AlShareef, Sahar, Ling, Yu, Butt, Haroon, Mariappan, Kiruthiga G., Benhamed, Moussa, Mahfouz, Magdy M.
Publicado 2017

The Arabidopsis SWI/SNF protein BAF60 mediates seedling growth control by modulating DNA accessibility

por Jégu, Teddy, Veluchamy, Alaguraj, Ramirez-Prado, Juan S., Rizzi-Paillet, Charley, Perez, Magalie, Lhomme, Anaïs, Latrasse, David, Coleno, Emeline, Vicaire, Serge, Legras, Stéphanie, Jost, Bernard, Rougée, Martin, Barneche, Fredy, Bergounioux, Catherine, Crespi, Martin, Mahfouz, Magdy M., Hirt, Heribert, Raynaud, Cécile, Benhamed, Moussa
Publicado 2017

MAPK-triggered chromatin reprogramming by histone deacetylase in plant innate immunity

por Latrasse, David, Jégu, Teddy, Li, Huchen, de Zelicourt, Axel, Raynaud, Cécile, Legras, Stéphanie, Gust, Andrea, Samajova, Olga, Veluchamy, Alaguraj, Rayapuram, Naganand, Ramirez-Prado, Juan Sebastian, Kulikova, Olga, Colcombet, Jean, Bigeard, Jean, Genot, Baptiste, Bisseling, Ton, Benhamed, Moussa, Hirt, Heribert
Publicado 2017

Dietary oleic acid regulates hepatic lipogenesis through a liver X receptor-dependent signaling

por Ducheix, Simon, Montagner, Alexandra, Polizzi, Arnaud, Lasserre, Frédéric, Régnier, Marion, Marmugi, Alice, Benhamed, Fadila, Bertrand-Michel, Justine, Mselli-Lakhal, Laila, Loiseau, Nicolas, Martin, Pascal G., Lobaccaro, Jean-Marc, Ferrier, Laurent, Postic, Catherine, Guillou, Hervé
Publicado 2017

AMP-activated protein kinase – not just an energy sensor

por Hardie, David Grahame, Lin, Sheng-Cai
Publicado 2017

Ecological and evolutionary significance of a lack of capacity for extended developmental arrest in crocodilian eggs

por Williamson, Sean A., Evans, Roger G., Manolis, S. Charlie, Webb, Grahame J., Reina, Richard D.
Publicado 2017

Development and optimization of a differentiated airway epithelial cell model of the bovine respiratory tract

por Cozens, Daniel, Grahame, Edward, Sutherland, Erin, Taylor, Geraldine, Berry, Catherine C., Davies, Robert L.
Publicado 2018

The Rosa genome provides new insights into the domestication of modern roses

por Raymond, Olivier, Gouzy, Jérôme, Just, Jérémy, Badouin, Hélène, Verdenaud, Marion, Lemainque, Arnaud, Vergne, Philippe, Moja, Sandrine, Choisne, Nathalie, Pont, Caroline, Carrère, Sébastien, Caissard, Jean-Claude, Couloux, Arnaud, Cottret, Ludovic, Aury, Jean-Marc, Szecsi, Judit, Latrasse, David, Madoui, Mohammed-Amin, François, Léa, Fu, Xiaopeng, Yang, Shu-Hua, Dubois, Annick, Piola, Florence, Larrieu, Antoine, Perez, Magali, Labadie, Karine, Perrier, Lauriane, Govetto, Benjamin, Labrousse, Yoan, Villand, Priscilla, Bardoux, Claudia, Boltz, Véronique, Lopez-Roques, Céline, Heitzler, Pascal, Vernoux, Teva, Vandenbussche, Michiel, Quesneville, Hadi, Boualem, Adnane, Bendahmane, Abdelhafid, Liu, Chang, Le Bris, Manuel, Salse, Jérôme, Baudino, Sylvie, Benhamed, Moussa, Wincker, Patrick, Bendahmane, Mohammed
Publicado 2018

Isoform-specific AMPK association with TBC1D1 is reduced by a mutation associated with severe obesity

por Thomas, Elaine C., Hook, Sharon C., Gray, Alexander, Chadt, Alexandra, Carling, David, Al-Hasani, Hadi, Heesom, Kate J., Hardie, D. Grahame, Tavaré, Jeremy M.
Publicado 2018

INDETERMINATE-DOMAIN 4 (IDD4) coordinates immune responses with plant-growth in Arabidopsis thaliana

por Völz, Ronny, Kim, Soon-Kap, Mi, Jianing, Rawat, Anamika A., Veluchamy, Alaguraj, Mariappan, Kiruthiga G., Rayapuram, Naganand, Daviere, Jean-Michel, Achard, Patrick, Blilou, Ikram, Al-Babili, Salim, Benhamed, Moussa, Hirt, Heribert
Publicado 2019

A novel null mutation in the pyruvate dehydrogenase phosphatase catalytic subunit gene (PDP1) causing pyruvate dehydrogenase complex deficiency

por Bedoyan, Jirair K., Hecht, Leah, Zhang, Shulin, Tarrant, Stacey, Bergin, Ann, Demirbas, Didem, Yang, Edward, Shin, Ha Kyung, Grahame, George J., DeBrosse, Suzanne D., Hoppel, Charles L., Kerr, Douglas S., Berry, Gerard T.
Publicado 2019

Modelling of population structure through contemporary groups in genetic evaluation

por Klápště, Jaroslav, Suontama, Mari, Dungey, Heidi S, Telfer, Emily J, Stovold, Grahame T
Publicado 2019

Development of a Novel Cell-Permeable Protein–Protein Interaction Inhibitor for the Polo-box Domain of Polo-like Kinase 1

por Huggins, David J., Hardwick, Bryn S., Sharma, Pooja, Emery, Amy, Laraia, Luca, Zhang, Fengzhi, Narvaez, Ana J., Roberts-Thomson, Meredith, Crooks, Alex T., Boyle, Robert G., Boyce, Richard, Walker, David W., Mateu, Natalia, McKenzie, Grahame J., Spring, David R., Venkitaraman, Ashok R.
Publicado 2019

Integrative genome-wide analysis reveals the role of WIP proteins in inhibition of growth and development

por Roldan, Maria Victoria Gomez, Izhaq, Farhaj, Verdenaud, Marion, Eleblu, John, Haraghi, Aimen, Sommard, Vivien, Chambrier, Pierre, Latrasse, David, Jégu, Teddy, Benhamed, Moussa, Szécsi, Judit, Bendahmane, Mohammed, Boualem, Adnane, Bendahmane, Abdelhafid
Publicado 2020

The cardiolipin-binding peptide elamipretide mitigates fragmentation of cristae networks following cardiac ischemia reperfusion in rats

por Allen, Mitchell E., Pennington, Edward Ross, Perry, Justin B., Dadoo, Sahil, Makrecka-Kuka, Marina, Dambrova, Maija, Moukdar, Fatiha, Patel, Hetal D., Han, Xianlin, Kidd, Grahame K., Benson, Emily K., Raisch, Tristan B., Poelzing, Steven, Brown, David A., Shaikh, Saame Raza
Publicado 2020

Push Button Population Health: The SMART/HL7 FHIR Bulk Data Access Application Programming Interface

por Mandl, Kenneth D., Gottlieb, Daniel, Mandel, Joshua C., Ignatov, Vladimir, Sayeed, Raheel, Grieve, Grahame, Jones, James, Ellis, Alyssa, Culbertson, Adam
Publicado 2020