“…Although there appeared to be between province differences in pandemic waves and vaccination strategies, the VE against COVID-19 infection as well as related severe outcome appeared to be not statistically significantly different. A nationally representative VE could be estimated using pooled data from multiple regions.…”
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“…“Metabolic memory” represents the epigenetic changes induced by chronic hyperglycaemia, despite the correction of the glucose levels themselves. …”
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“…CONCLUSION: These data represent the largest annual reported study of plastic surgery resident aesthetic surgical and injectable procedures and outcomes, demonstrating the high volume and productivity of the NYU Resident Aesthetic Surgery Clinic. …”
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“…RESULTS: Preliminary identifications indicate the presence of at least 727 unique fungal species within the Reserve, representing 4 phyla, 17 classes, 40 orders, 101 families, and 229 genera. …”
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“…The patient is best represented by a high-fidelity mannequin such as Trauma HAL(®) (Miami, FL USA) https://www.gaumard.com/products/trauma/trauma-halr), with a monitor displaying vital signs and voice-response capabilities. …”
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“…INTRODUCTION: Annually, there are approximately 1.4 billon lightning strikes around the world; of these, an estimated 24,000 strikes cause significant injury or death.1 In the United States, there are approximately 400 lightning-related injuries every year resulting in 40 average annual deaths.1 Although only one in approximately 14,000 people will ever be struck by lightning, this still represents a significant injury mechanism for which emergency department providers must be prepared.2 Lightning is formed by static electricity built up due to ice crystals in clouds which creates a differential charge between the cloud and another object, such as the ground. …”
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“…These were not clearly tied to patient demographic factors, and could represent intrinsic differences in the response to injury. …”
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“…OBJECTIVES: Nonoperative treatment represents a safe, guideline-based approach for meniscal injuries, but it is unclear why or how it works. …”
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“…BACKGROUND: Cardiovascular disease (CVD) is a major cause of mortality in the United States, representing the highest total expenditures among major diseases. …”
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“…CONCLUSIONS: This evaluation suggests that IFN β-1a SC injection, IFNβ-1b SC injection, and glatiramer acetate represent the most cost-effective DMDs for the treatment of RRMS, where cost-effectiveness is defined as cost per relapse avoided, assuming that (a) the RRR in relapses and disease progression steps calculated from multiple DMD placebo-controlled clinical trials reflect real differences among DMDs over 2 years; and (b)resource unit costs derived from published sources reflect economic consequences of relapses and disease progression. …”
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“…METHODS: This was a retrospective claims analysis of the PharMetrics Patient-Centric database over an approximately 7-year period from January 1997 to April 2004. The database represents about 43 million members in commercial health plans. …”
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“…Treatment attributes represented the expected outcomes of treatment: severity of daily symptoms, frequency of flare-ups, serious disease complications, oral steroid use, and the risks of 3 potentially fatal SAEs lymphoma, serious or opportunistic infections, and progressive multifocal leukoencephalopathy (PML) during 10 years of treatment. …”
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“…To our knowledge, this represents the largest cohort of ICI-pretreated patients with RCC prospectively treated in a clinical trial. …”
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“…However, whether Aβ(42) and amyR have different meanings and whether Aβ(40) represents more than an Aβ(42)-corrective factor remain to be clarified. …”
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“…A total of seven distinct clusters representing different temporal patterns of miRNA expression were discovered. …”
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“…In retrospect, with the diagnosis of VEXAS in mind, it is likely that this improvement represented disease fluctuation rather than response to antibiotics. …”
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“…Bone turnover markers increased from BL (n=7) (CT(X)=253±111 pg/mL; P1NP=34±10 mcg/L) by P3W24 (n=13) (CT(X)=744±565; P1NP=104±87) and remained elevated at LTEM12 (CT(X)=988±652; P1NP=83±49 [p<0.01]. This study represents a molecularly targeted, precision medicine approach to the treatment of ADH1. …”
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“…Background/Purpose: Teriparatide, an effective osteoanabolic agent, requires a chronic regimen of daily subcutaneous (SC) injections, representing a burden for patients which may interfere with compliance and quality of life. …”
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“…Background: Biotherapeutics offer effective treatments for reproductive disorders, but require painful parenteral (e.g., subcutaneous (SC)) injections, representing a burden for patients which interferes with comfort and quality of life. …”
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“…The identification of these molecular targets and pathways represents a significant step forward in understanding the molecular basis of Danshenol C's therapeutic effects in PF. …”
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