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  1. 354061
    Publicado 2022
    “…ANVISA, the holder of specialized knowledge in the health sector in the exercise of the “prior consent” procedure, should enter into any aspects of the pharmaceutical products or processes that allow it to infer whether the granting of the exclusivity right will represent potential harm to SUS public policies aimed at guaranteeing pharmaceutical assistance to the population (even if they are extracted from the patentability requirements i.e. novelty, inventive step and industrial application). 11. …”
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    “Penciclovir”: Decision of the Superior Court of Justice of Brazil (Superior Tribunal de Justiça) 5 August 2021 – Case No. 1.543.826 – RJ (2015/0173736-6)
  2. 354062
    “…Finally, C19-RS was strongly associated (r=0·61, p=0·00031) with a whole blood transcriptional module representing dysregulation of coagulation and platelet aggregation pathways. …”
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    Constructing custom-made radiotranscriptomic signatures of vascular inflammation from routine CT angiograms: a prospective outcomes validation study in COVID-19
  3. 354063
    “…A criterion based on the alternative consideration of ≥ 50% reduction in MIDAS score or MMDs in the first three months of treatment represents a more precise and inclusive option. TRIAL REGISTRATION: The trial was retrospectively registered at www.clinicaltrials.gov (NCT05442008). …”
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    Does MIDAS reduction at 3 months predict the outcome of erenumab treatment? A real-world, open-label trial
  4. 354064
    por Melville, Andrew
    Publicado 2022
    “…Whether sulfasalazine is truly less effective in this specific disease domain, or this simply represents a lack of supporting evidence, is debatable. …”
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    Online Artículo Texto
    OA12 Dactylitis in PsA: aetiology, clinical significance, & treatment implications
  5. 354065
    “…KEY LEARNING POINTS/CONCLUSION: Anti-MDA5 positive ILD represents a cohort of children requiring a more aggressive immunosuppressive therapies to optimise and prevent further deterioration in their clinical respiratory function. …”
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    P14 Challenges in treating anti-melanoma differentiation associated gene 5 (MDA5) antibody positive juvenile dermatomyositis (JDM) with interstitial lung disease (ILD) complicated by pneumocytis jirovecii pneumonia (PCP): a case report
  6. 354066
    “…DESIGN, SETTING, AND PARTICIPANTS: This prospective cohort study used data from 15 949 participants in the China Health and Retirement Longitudinal Study (CHARLS) and the US Health and Retirement Study (HRS), 2 ongoing nationally representative cohort studies enrolling community-dwelling older people. …”
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    Online Artículo Texto
    Association of Cystatin C Kidney Function Measures With Long-term Deficit-Accumulation Frailty Trajectories and Physical Function Decline
  7. 354067
    “…Data on participant race and ethnicity were not reported because they were not uniformly collected in the original cohorts and were therefore not representative or informative. EXPOSURES: SARS-CoV-2–positive and SARS-CoV-2–negative respiratory illness episodes. …”
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    Online Artículo Texto
    Longitudinal Household Assessment of Respiratory Illness in Children and Parents During the COVID-19 Pandemic
  8. 354068
    “…SARS-CoV-2 infections with the delta (B.1.617.2; 72 [40%] of 180), alpha (B.1.1.7; 37 [21%]), omicron (B.1.1.529; 38 [21%]), and EU1 (B.1.177; 28 [16%]) variants were represented. All 180 participants received at least one dose of treatment and four participants discontinued the study (one in the molnupiravir group and three in the placebo group). …”
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    Molnupiravir versus placebo in unvaccinated and vaccinated patients with early SARS-CoV-2 infection in the UK (AGILE CST-2): a randomised, placebo-controlled, double-blind, phase 2 trial
  9. 354069
    “…Chemotherapy resistance represents a significant clinical challenge and is the main reason for poor ovarian cancer prognosis. …”
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    Platinum-resistance in epithelial ovarian cancer: an interplay of epithelial–mesenchymal transition interlinked with reprogrammed metabolism
  10. 354070
    “…Individuals were enrolled from all 18 districts of Hong Kong, according to a predefined age-stratified quota, primarily by random digit dialing (generating suitable eight-digit local telephone numbers by randomly picking sets of the first four digits from a sampling frame, and randomly generating the last four digits), and supplemented by our existing cohorts (which included cohorts for studying influenza vaccination from school-based vaccination programmes and cohorts for SARS-CoV-2 seroprevalence from the community), to ensure representativeness of the population in Hong Kong. Participants did weekly rapid antigen testing with a self-collected pooled nasal and throat swab, regardless of symptom and exposure status, from March 1 to April 15, 2022. …”
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    Online Artículo Texto
    Effectiveness of BNT162b2 and CoronaVac COVID-19 vaccination against asymptomatic and symptomatic infection of SARS-CoV-2 omicron BA.2 in Hong Kong: a prospective cohort study
  11. 354071
    “…The P-value reported represents the overall comparison of the intervention study phases versus control (routine care). …”
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    87. Impact of Universal Decolonization With and Without Enhanced Cleaning on MultiDrug-Resistant Organism (MDRO) Body-Site Carriage and Environmental Contamination in Nursing Homes (NHs): The CLEAN Study
  12. 354072
    “…Virtual spherical defects representing lytic lesions were placed at 32 defined locations based on axial (4 axial positions: neck, intertrochanteric, subtrochanteric or diaphyseal) and circumferential (8 circumferential: 45-degree intervals) positions. …”
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    Modification to Mirels scoring system location component improves fracture prediction for metastatic disease of the proximal femur
  13. 354073
    “…DISCLAIMER: This guideline represents the views of ESHRE, which were achieved after careful consideration of the scientific evidence available at the time of preparation. …”
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    ESHRE guideline: medically assisted reproduction in patients with a viral infection/disease
  14. 354074
    “…Potential participants represented the full range of sociodemographic classifications of neighborhoods. …”
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    Prosocial and Aggressive Behavior: A Longitudinal Study
  15. 354075
    “…DISCLAIMER: This guideline represents the views of ESHRE, which were achieved after careful consideration of the scientific evidence available at the time of preparation. …”
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    ESHRE guideline: recurrent pregnancy loss: an update in 2022(†)
  16. 354076
    Publicado 1990
    Mapa
    Atlas nacional de México /
  17. 354077
    por Jia, S., Shen, C.P., Adachi, I., Aihara, H., Said, S. Al, Asner, D.M., Atmacan, H., Aushev, T., Ayad, R., Babu, V., Behera, P., Belous, K., Bennett, J., Bessner, M., Bhardwaj, V., Bhuyan, B., Bilka, T., Bobrov, A., Bodrov, D., Bonvicini, G., Borah, J., Bračko, M., Branchini, P., Browder, T.E., Budano, A., Campajola, M., Červenkov, D., Chang, M.-C., Chang, P., Chekelian, V., Chen, A., Cheon, B.G., Chilikin, K., Cho, H.E., Cho, K., Cho, S.-J., Choi, S.-K., Choi, Y., Choudhury, S., Cinabro, D., Cunliffe, S., Das, S., Dash, N., De Nardo, G., De Pietro, G., Dhamija, R., Di Capua, F., Doležal, Z., Dong, T.V., Epifanov, D., Ferber, T., Ferlewicz, D., Fulsom, B.G., Garg, R., Gaur, V., Gabyshev, N., Giri, A., Goldenzweig, P., Golob, B., Graziani, E., Guan, Y., Gudkova, K., Hadjivasiliou, C., Hara, T., Hayasaka, K., Hayashii, H., Hedges, M.T., Hou, W.-S., Inami, K., Inguglia, G., Ishikawa, A., Itoh, R., Iwasaki, M., Iwasaki, Y., Jacobs, W.W., Jang, E.-J., Jin, Y., Joo, K.K., Kahn, J., Kaliyar, A.B., Kang, K.H., Kawasaki, T., Kiesling, C., Kim, C.H., Kim, D.Y., Kim, K.-H., Kim, Y.-K., Kinoshita, K., Kodyš, P., Kohani, S., Konno, T., Korobov, A., Korpar, S., Kovalenko, E., Križan, P., Kroeger, R., Krokovny, P., Kumar, M., Kumar, R., Kumara, K., Kwon, Y.-J., Lam, T., Laurenza, M., Lee, S.C., Li, J., Li, L.K., Li, Y., Li, Y.B., Gioi, L. Li, Libby, J., Lieret, K., Liventsev, D., Martini, A., Masuda, M., Matsuda, T., Matvienko, D., Maurya, S.K., Meier, F., Merola, M., Metzner, F., Miyabayashi, K., Mizuk, R., Mohanty, G.B., Nakao, M., Narwal, D., Natkaniec, Z., Natochii, A., Nayak, L., Nisar, N.K., Nishida, S., Nishimura, K., Ogawa, K., Ogawa, S., Ono, H., Oskin, P., Pakhlov, P., Pakhlova, G., Pang, T., Pardi, S., Park, S.-H., Patra, S., Paul, S., Pedlar, T.K., Pestotnik, R., Piilonen, L.E., Podobnik, T., Prencipe, E., Prim, M.T., Röhrken, M., Rostomyan, A., Rout, N., Russo, G., Sahoo, D., Sandilya, S., Sangal, A., Santelj, L., Sanuki, T., Savinov, V., Schnell, G., Schueler, J., Schwanda, C., Seino, Y., Senyo, K., Sevior, M.E., Shapkin, M., Sharma, C., Shebalin, V., Shiu, J.-G., Shwartz, B., Singh, J.B., Sokolov, A., Solovieva, E., Stanič, S., Starič, M., Stottler, Z.S., Sumihama, M., Sumisawa, K., Sumiyoshi, T., Sutcliffe, W., Takizawa, M., Tamponi, U., Tanida, K., Tenchini, F., Trabelsi, K., Uchida, M., Uehara, S., Uglov, T., Unno, Y., Uno, K., Uno, S., Urquijo, P., Vahsen, S.E., Van Tonder, R., Varner, G., Vinokurova, A., Waheed, E., Wang, D., Wang, E., Wang, M.-Z., Watanuki, S., Won, E., Yabsley, B.D., Yan, W., Yang, S.B., Ye, H., Yelton, J., Yin, J.H., Yusa, Y., Zhai, Y., Zhang, Z.P., Zhilich, V., Zhukova, V.
    Publicado 2021
    “…We set the upper limits at 90% credibility level (C.L.) on the product branching fractions for <math display="inline"><mi mathvariant="normal">ϒ</mi><mo stretchy="false">(</mo><mn>1</mn><mi>S</mi><mo stretchy="false">)</mo><mo stretchy="false">→</mo><mi>γ</mi><msup><mi>A</mi><mn>0</mn></msup></math> and <math display="inline"><msup><mi>A</mi><mn>0</mn></msup><mo stretchy="false">→</mo><msup><mi>τ</mi><mo>+</mo></msup><msup><mi>τ</mi><mo>-</mo></msup></math> varying from <math display="inline"><mn>3.8</mn><mo>×</mo><msup><mn>10</mn><mrow><mo>-</mo><mn>6</mn></mrow></msup></math> to <math display="inline"><mn>1.5</mn><mo>×</mo><msup><mn>10</mn><mrow><mo>-</mo><mn>4</mn></mrow></msup></math>. Our results represent an approximately twofold improvement on the current world best upper limits for the <math display="inline"><mrow><mi mathvariant="normal">ϒ</mi><mo stretchy="false">(</mo><mn>1</mn><mi>S</mi><mo stretchy="false">)</mo><mo stretchy="false">→</mo><mi>γ</mi><msup><mrow><mi>A</mi></mrow><mrow><mn>0</mn></mrow></msup><mo stretchy="false">(</mo><mo stretchy="false">→</mo><msup><mrow><mi>τ</mi></mrow><mrow><mo>+</mo></mrow></msup><msup><mrow><mi>τ</mi></mrow><mrow><mo>-</mo></mrow></msup><mo stretchy="false">)</mo></mrow></math> production. …”
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    Search for a light Higgs boson in single-photon decays of $\Upsilon(1S)$ using $\Upsilon(2S) \to \pi^+ \pi^- \Upsilon(1S)$ tagging method
  18. 354078
    por Rhee, Soo-Yon, Blanco, Jose Luis, Jordan, Michael R., Taylor, Jonathan, Lemey, Philippe, Varghese, Vici, Hamers, Raph L., Bertagnolio, Silvia, de Wit, Tobias F. Rinke, Aghokeng, Avelin F., Albert, Jan, Avi, Radko, Avila-Rios, Santiago, Bessong, Pascal O., Brooks, James I., Boucher, Charles A. B., Brumme, Zabrina L., Busch, Michael P., Bussmann, Hermann, Chaix, Marie-Laure, Chin, Bum Sik, D’Aquin, Toni T., De Gascun, Cillian F., Derache, Anne, Descamps, Diane, Deshpande, Alaka K., Djoko, Cyrille F., Eshleman, Susan H., Fleury, Herve, Frange, Pierre, Fujisaki, Seiichiro, Harrigan, P. Richard, Hattori, Junko, Holguin, Africa, Hunt, Gillian M., Ichimura, Hiroshi, Kaleebu, Pontiano, Katzenstein, David, Kiertiburanakul, Sasisopin, Kim, Jerome H., Kim, Sung Soon, Li, Yanpeng, Lutsar, Irja, Morris, Lynn, Ndembi, Nicaise, NG, Kee Peng, Paranjape, Ramesh S., Peeters, Martine, Poljak, Mario, Price, Matt A., Ragonnet-Cronin, Manon L., Reyes-Terán, Gustavo, Rolland, Morgane, Sirivichayakul, Sunee, Smith, Davey M., Soares, Marcelo A., Soriano, Vincent V., Ssemwanga, Deogratius, Stanojevic, Maja, Stefani, Mariane A., Sugiura, Wataru, Sungkanuparph, Somnuek, Tanuri, Amilcar, Tee, Kok Keng, Truong, Hong-Ha M., van de Vijver, David A. M. C., Vidal, Nicole, Yang, Chunfu, Yang, Rongge, Yebra, Gonzalo, Ioannidis, John P. A., Vandamme, Anne-Mieke, Shafer, Robert W.
    Publicado 2015
    “…Inherent limitations of this study are that some cohorts may not represent the broader regional population and that studies were heterogeneous with respect to duration of infection prior to sampling. …”
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    Geographic and Temporal Trends in the Molecular Epidemiology and Genetic Mechanisms of Transmitted HIV-1 Drug Resistance: An Individual-Patient- and Sequence-Level Meta-Analysis
  19. 354079
    por Ibrahim, Mo, Bingham, Alpheus
    Publicado 2009
    “…When such systems came into broad use, i.e., chat rooms, usenets, innocentive, etc., and were subsequently studied, it was often found that the greatest probability of solution lies in the "long tail" of the function rather than in the head representing formally vetted 'experts.' Insight into a problem is often the intersection of training, experience, metaphor and provocation (think Archimedes). …”
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    The Citizen Cyberscience Lectures - 1) Mobile phones and Africa: a success story 2) Citizen Problem Solving
  20. 354080
    por Wysocka-Rabin, A
    Publicado 2013
    “…These studies applied the Monte Carlo technique to investigate the feasibility of performing Intensity Modulated Radiotherapy (IMRT) by scanning with a narrow photon beam. This approach represents an alternative to techniques that generate beam modulation by absorption, such as MLC, individually-manufactured compensators, and special tomotherapy modulators. …”
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    info:eu-repo/semantics/article
    Advances in conformal radiotherapy: using Monte Carlo Code to design new IMRT and IORT accelerators and interpret CT numbers
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