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354141por Ramakrishnan, Sanjay, Nicolau, Dan V, Langford, Beverly, Mahdi, Mahdi, Jeffers, Helen, Mwasuku, Christine, Krassowska, Karolina, Fox, Robin, Binnian, Ian, Glover, Victoria, Bright, Stephen, Butler, Christopher, Cane, Jennifer L, Halner, Andreas, Matthews, Philippa C, Donnelly, Louise E, Simpson, Jodie L, Baker, Jonathan R, Fadai, Nabil T, Peterson, Stefan, Bengtsson, Thomas, Barnes, Peter J, Russell, Richard E K, Bafadhel, Mona“…BACKGROUND: Multiple early reports of patients admitted to hospital with COVID-19 showed that patients with chronic respiratory disease were significantly under-represented in these cohorts. We hypothesised that the widespread use of inhaled glucocorticoids among these patients was responsible for this finding, and tested if inhaled glucocorticoids would be an effective treatment for early COVID-19. …”
Publicado 2021
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354142“…Artesunate‐atovaquone‐proguanil and the development of parasite resistance may represent an area for further research.…”
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354143por Varma, Vijay R., Wang, Youjin, An, Yang, Varma, Sudhir, Bilgel, Murat, Doshi, Jimit, Legido-Quigley, Cristina, Delgado, João C., Oommen, Anup M., Roberts, Jackson A., Wong, Dean F., Davatzikos, Christos, Resnick, Susan M., Troncoso, Juan C., Pletnikova, Olga, O’Brien, Richard, Hak, Eelko, Baak, Brenda N., Pfeiffer, Ruth, Baloni, Priyanka, Mohmoudiandehkordi, Siamak, Nho, Kwangsik, Kaddurah-Daouk, Rima, Bennett, David A., Gadalla, Shahinaz M., Thambisetty, Madhav“…We hypothesize that dysregulation of BA signaling pathways in the brain may represent a plausible biologic mechanism underlying these results. …”
Publicado 2021
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354144por Waldvogel, Thomas, Wagschal, Uwe, Metz, Thomas, Becker, Bernd, Feiten, Linus, Weishaupt, Samuel“…Although our analysis focuses merely on the partisan groups of the two candidates which parties are represented in the TV debates, in summarizing the results, we consider the question of construct validity (FF1.1) to be positively decided. …”
Publicado 2021
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354145por Lutfi, Forat, Siglin, Jonathan, Sanchez-Petitto, Gabriela, Bukhari, Ali, Gottlieb, David, Kim, Dong Won, Cooper, Brandon, Fleyshman, Michelle, De Miguel Perez, Diego, Kleinberg, Michael, Lapidus, Rena G, Rapoport, Aaron P., Fan, Xiaoxuan, Dahiya, Saurabh“…These findings are consistent with the fact that both CG and NCG, as hospitalized patients, represent the most severely ill COVID patient cohort. …”
Publicado 2020
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354146por Mussetti, Alberto, Salas Gay, Maria Queralt, Condom, Maria, Antonio, Maite, Ochoa, Cristian, Ivan, Iulia, Jiménez Ruiz De La Torre, David, Sanz-Linares, Gabriela Isabel, Ansoleaga, Belen, Parody, Rocio, Bazarbachi, Ali, Sureda Balari, Anna“…Technological problems still represent a barrier to a wider application of telehealth monitoring systems in the medical setting. …”
Publicado 2020
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354147por Claudiani, Simone, Rosadas, Carolina, McClure, Myra, Khan, Maryam, Tedder, Richard S., Innes, Andrew J., Milojkovic, Dragana, Apperley, Jane“…[Image: see text] Background: The new SARS-CoV-2-induced disease (COVID-19) pandemic has represented a huge challenge for the health systems and has been responsible for almost 700.000 deaths worldwide as of 1(st) August 2020. …”
Publicado 2020
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354148por Qu, Jiayao, Li, Jia, Zhang, Yaming, He, Rongzhang, Liu, Xiangting, Gong, Ke, Duan, Lili, Luo, Weihao, Hu, Zheng, Wang, Gengsheng, Xia, Chenglai, Luo, Dixian“…CONCLUSIONS: AKR1B10 promotes the proliferation, migration and invasion of breast cancer cells via the PI3K/AKT/NF-κB signaling pathway and represents a novel prognostic indicator as well as a potential therapeutic target in breast cancer. …”
Publicado 2021
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354149“…CASE REPORT - INTRODUCTION: Eye involvement represents a common finding in patients with systemic autoimmune diseases, particularly rheumatoid arthritis, Sjogren syndrome, seronegative spondyloarthropathy, and variable vasculitides e.g., sarcoid, antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis, GCA, Behcet’s and Cogan’s syndrome. …”
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354150por McLaren, Rodney A., Trejo, Fatima Estrada, Blitz, Matthew J., Bianco, Angela, Limaye, Meghana, Brustman, Lois, Bernstein, Peter S., Roman, Ashley S., Stone, Joanne, Minkoff, Howard“…The hospitals located within New York City (N=10) had a larger drop in birth rate in the last 2 years (−1947, 18.9%) than in the hospitals located in Long Island (N=4) (−581, 13.4%). Figure 2 represents the total live births by individual hospitals in the different time frames. …”
Publicado 2021
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354151por Wicke, Nina“…These quality dimensions represent to a certain extent ‘basic prerequisites’ which enable participants to trust scientific findings and, where applicable, to take them into account when making decisions. …”
Publicado 2021
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354152por Singh, Bandana, Kanack, Adam, Bayas, Antonios, George, Gemlyn, Abou-Ismail, Mouhamed Yazan Abou, Kohlhagen, Mindy, Christ, Monika, Naumann, Markus, Moser, Karen A, Smock, Kristi J, Grazioli, Alison, Murray, David L, Padmanabhan, Anand“…Mass spectrometric evaluation of anti-PF4 antibodies isolated from VITT patients demonstrated monoclonal anti-PF4 antibodies in three patients, and bi- and tri-clonal antibodies in one patient each (a representative monoclonal antibody anti-PF4 antibody is shown in Fig 1B). …”
Publicado 2021
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354153por Spyridis, Nikolaos, Karavalakis, Georgios, Mallouri, Despina, Eftychidis, Ioannis, Dolgyras, Panagiotis, Stavroyianni, Niki, Lalayanni, Chrysavgi, Batsis, Ioannis, Sakellari, Ioanna, Anagnostopoulos, Achilles, Sotiropoulos, Damianos“…Most of them (92%) acquired infection outside a hospital setting. 13% of pts were asymptomatic and diagnosis was confirmed only with positive RT-PCR test. The most common represented malignancies were NHL 26%, CLL 20% and acute leukemias 13.5%, while 15% of pts underwent transplantation (HCT). …”
Publicado 2021
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354154por Aumann, Shlomzion, Tsubary, Uria, Israel, Sarah, Ben Yehuda, Dina, Lavie, David, Goldschmidt, Neta, Vainstein, Vladimir, Libster, Diana, Saban, Revital, Shaulov, Adir, Avni, Batia, Nachmias, Boaz, Grisariu, Sigal, Paltiel, Ora, Gatt, Moshe, Zimran, Eran“…These studies, however, were strongly biased towards hospitalized patients, and poorly represented patients who experienced a milder course of COVID-19, not requiring hospitalization. …”
Publicado 2021
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354155por Gavriilaki, Eleni, Touloumenidou, Tasoula, Tsiftsoglou, Stefanos, Tragiannidis, Athanasios, Farmaki, Evangelia, Panagopoulou, Paraskevi, Michailidou, Elisavet, Koravou, Evdoxia, Koutra, Maria, Iosifidis, Ilias, Papadimitriou, Eleni, Papadopoulou-Alataki, Efimia, Papayanni, Penelope Georgia, Varelas, Christos, Papalexandri, Apostolia, Evangeliou, Athanasios, Galli-Tsinopoulou, Assimina, Zafeiriou, Dimitrios, Roilides, Emmanuel, Sakellari, Ioanna, Anagnostopoulos, Achilles“…We identified common variants, some well represented by relatively high frequencies (>70%) (rs11098044 in CFI, rs1061170 in CFH and rs12711521 in MASP2) and others less abundant, but varying considerably between the hospitalized group, the non-admitted group and the MIS-C individuals (rs2230199 in C3, rs1065489 in CFH, rs12614 and rs641153 in CFB, rs1800450 in MBL2, rs2273346 and rs72550870 in MASP2, rs72549154 in MASP3 and rs7567833 in COLEC11, all highlighted in Figure in red).). …”
Publicado 2021
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354156por Vasudevan, Lavanya, Glenton, Claire, Henschke, Nicholas, Maayan, Nicola, Eyers, John, Fønhus, Marita S, Tamrat, Tigest, Mehl, Garrett L, Lewin, Simon“…They focussed on identification of births and deaths in rural, remote, or marginalised populations who are typically under‐represented in civil registration processes or traditionally seen as having poor access to health services. …”
Publicado 2021
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354157por Phares, Christina R., Liu, Yecai, Wang, Zanju, Posey, Drew L., Lee, Deborah, Jentes, Emily S., Weinberg, Michelle, Mitchell, Tarissa, Stauffer, William, Self, Julie L., Marano, Nina“…Postarrival follow-up examinations, which were completed for 88,190 persons and identified 475 cases of culture-positive TB, represent an important opportunity to further limit spread of TB disease in the United States by identifying and providing, if needed, preventive care for those with LTBI or treatment for those with disease. …”
Publicado 2022
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354158por Moring, John, Straud, Casey, Penzien, Donald, Resick, Patricia, Peterson, Alan, Jaramillo, Carlos, Eapen, Blessen, McGeary, Cindy, Mintz, Jim, Hale, Willie, McGeary, Don“…Standardized canonical coefficients indicated that the PTSD subscales Reexperiencing (b = 0.64) and Negative Alterations in Cognition and Mood (b = 0.55) were the most representative of the identified canonical dimension. …”
Publicado 2020
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354159por Rajagopala, Lavanya, Dandeniya, Chathurika, Janagan, Shalene, Gunathilaka, Mahesh, Perera, Hasanthi, Karunarathna, Dhanushka, Jagoda, Jayathri“…Further research is needed to understand whether a high bone turnover is specific to MAFB gene mutation and if MCTO may represent a form of idiopathic juvenile osteoporosis in which short bones are more severely affected than long bones.…”
Publicado 2021
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354160por McKenna, Dearbhla, McLaughlin, Diarmuid, McLoone, Eibhlin, Campbell, Cathy, Rooney, Madeline, McAvoy, Clara“…Ocular involvement represents 10—20% of the initial presenting feature. …”
Publicado 2021
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