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354261por Raymer, Michael G“…Introduction: Physics and Its Relation to Computer and Internet Technologies Physics, Silicon, and the "Magic" behind the Internet Age A Zoomed-In Look inside a Computer Timeline of Great Discoveries and Inventions in Physics and Computer and Communication Technologies The Methods and Significance of Science The Relation of Science and Information Technology Social Impacts: Science and Technology Mathematics: The Language of Science and Technology The Utility of Mathematics in Science and Technology Graphs Precision and Significant Digits Large and Small Numbers and Scientific Notation Real-World Example 2.1: Precision of Display Pixels Units for Physical Quantities Proportionality Binary Numbers The Concept of Information Exponential Growth Social Impacts: The Exponential Change of Nearly EverythingMechanics: Energy Enables Information TechnologyFrom Looms to Computers Speed, Acceleration, and Force In-Depth Look 3.1: Distance Traveled under Constant Acceleration Real-World Example 3.1: Seek Time of a Hard-Drive Head In-Depth Look 3.2: Net Force Vectors Real-World Example 3.2: Acceleration in Cathode-Ray TubesPrinciples of Mechanics Real-World Example 3.3: Force on a Hard-Drive Head The Physics of Energy Friction and Thermal Energy The Constancy of Energy Units for Mechanics Power Real-World Example 3.4: Motion Sensors in LaptopsSocial Impacts: Scientific Thought and Methods Have Arguably Changed the Course of Human History More Than Anything ElseMatter and Heat: Cooling Computers is Required by the Physics of ComputationFrom Steam Engines to ComputersMatter and AtomsGases, Liquids, and SolidsIn-Depth Look 4.1: Size and Numbers of AtomsReal-World Example 4.1: Growing Silicon Crystals for Computer ChipsPressure in a GasPressure in a LiquidPumps, Current, and ResistanceReal-World Example 4.2: A Water-Pressure-Operated ComputerTemperature The Ideal GasHeat and Thermal Energy TransferReal-World Example 4.3: Cooling Computer Chips Principles of Thermodynamics: Extracting Work from Heat Cooling Computers is Required by the Physics of Computation Social Impacts: The Industrial Revolution and the Information Revolution Electricity and Magnetism: The Workhorses of Information TechnologyElectricity and Magnetism Are the Basis of Computers and the Internet Electric ChargeIn-Depth Look 5.1: The Concept of Plus and Minus Electric ChargeElectric Forces: Coulomb's LawIn-Depth Look 5.2: The Discovery of the ElectronElectric FieldsIn-Depth Look 5.3: Electric Field LinesElectric Current and ConductorsElectrical Energy and VoltageReal-World Example 5.1: Capacitor Computer MemoryResistors, Conductors, and Ohm's LawElectrical Power MagnetismElectromagnetism Real-World Example 5.2: The Telegraph, Precursor to the Internet In-Depth Look 5.4: Magnetic Materials and Data StorageSocial Impacts: Innovation and Public Support of ScienceDigital Electronics and Computer LogicThe "Reasoning" Abilities of ComputersConcepts of LogicElectronic Logic CircuitsLogic Operations and DiagramsUsing Logic to Perform ArithmeticImplementing Logic with Electromagnetic SwitchesSupplemental Section: Boolean Search of Databases Chapter 7 Waves: Sound, Radio, and LightCommunicating with Sound, Radio, and Light Simple Harmonic Motion Damped and Complex Harmonic Motion Driven Harmonic Motion and Resonance In-Depth Look 7.1: Resonance Frequencies Real-World Example 7.1: Crystal Oscillators and Microprocessor Clocks WavesSimple Harmonic WavesInterference of WavesIn-Depth Look 7.2: Standing WavesSound WavesIn-Depth Look 7.3: BeatsWireless Radio WavesReal-World Example 7.2: AM RadioLet There Be Light WavesIn-Depth Look 7.4: Light PolarizationReal-World Example 7.3: LCD ScreensInterference of Light Social Impacts: Music, Science and Technology Analog and Digital CommunicationCommunication Systems: Analog and DigitalBasics of Analog RadioBasics of Digital Radio The Maximum Rate of Transmitting DataMaximum Data RateFrequency Multiplexing and BandwidthIn-Depth Look 8.1: Signal ReconstructionQuantum Physics of Atoms and MaterialsAtoms, Crystals, and ComputersThe Quantum Nature of Electrons and AtomsThe Experiments behind Quantum TheoryIn-Depth Look 9.1: Spectrum of Hydrogen AtomsThe Spinning of ElectronsThe Principles of Quantum PhysicsBuilding Up the AtomsReal-World Example 9.1: Fluorescent LampsElectrical Properties of MaterialsIn-Depth Look 9.2: Origin of the Energy Gap in Silicon CrystalsIn-Depth Look 9.3: Atomic Nature of Magnetic DomainsSocial Impacts: Science, Mysticism, and Pseudo-Science Semiconductor Physics: Transistors and CircuitsSilicon, Transistors, and Computers Controlling the Conductivity of Silicon p-n Junctions and Diodes Real-World Example 10.1: A Simple Crystal AM Radio ReceiverTransistors CMOS Computer Logic In-Depth Look 10.1: Water-Effect Transistors Miniaturization, Integrated Circuits, and Photolithography In-Depth Look 10.2: Bipolar Transistors Social Impacts: Labeling Every Object in the World Digital Memory and ComputersPhysics, Memory, and Computers Sequential Logic for Computer Memory Feedback Example #1: NOT Loop Feedback Example #2: One-Time Latch Static Random-Access Memory In-Depth Look 11.1: SRAM with Six Transistors Dynamic Random-Access Memory Nonvolatile Memory In-Depth Look 11.2: Quantum Tunneling Magnetic Tape and Hard Disk Memory Optical Compact Disk Memory Error Immunity of Digital Data The Structure of a Computer Hierarchy of Computer Memory Heat-Imposed Limits of Computers Representing Information in Computers using Codes Coding Images Data Compression Photons: Light Detectors and Light Emitting DiodesLight, Physics, and TechnologyThe Quantum Nature of Light-PhotonsPower and Energy in LightAbsorption of Light by Atoms and Crystals (or "How Einstein Got His Nobel Prize")In-Depth Look 12.1: Inability of Constant Voltage to Accelerate Electrons in an Insulator Real-World Example 12.1: Semiconductor Light DetectorsEmission of Light by Atoms and CrystalsReal-World Example 12.2: Light-Emitting DiodesSocial Impacts: Lighting the Darkness (Efficiently)Light and Optical Fibers for the InternetLight as a Communication MediumPropagation, Reflection and Transmission of LightLight in Transparent MediaRefraction of Light at a BoundaryReflection of Light at a BoundaryTotal Internal ReflectionPrisms and Speeds of Different Colored LightLenses and Curved MirrorsOptical Loss in Materials-The Clarity of Optical FiberLight GuidingOptical FibersLight Pulses in Optical FibersSocial Impacts: Total Immersion in a Sea of InformationLight Amplification and LasersAtoms and LasersThe Uniqueness of Laser LightAbsorption and Emission of Light by AtomsLaser ResonatorsIn-Depth Look 14.1: Laser Resonator FrequenciesHow a Laser WorksThe Helium-Neon LaserIn-Depth Look 14.2: Extreme Laser FactsVariable-Color Semiconductor LasersOvercoming Losses in Fiber-Optic SystemsQuantum Physics Description of LasersThe Semiconductor Diode LaserFiber-Optics CommunicationBandwidth and the Physics of WavesOverview of Fiber-Optical Communication SystemsModulating a Laser Beam with DataWavelength Multiplexing in Optical CommunicationThe Virtues of Lasers for Optical CommunicationHardware for Wavelength MultiplexingLaser Beam RoutingCommunication Networks and the InternetThe Physics behind the InternetThe Goals of Computer Communication NetworksNoise in Analog and Digital SystemsChallenges in NetworkingBroadcasting Networks and Switching NetworksFailure-Resistant CommunicationsWireless Mobile Cell Phone NetworksPropagation of Wireless Waves in TerrainSummary of Scientific Notation and UnitsSources and Credits for Quotes Used with PermissionGlossary.…”
Publicado 2009
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354262Publicado 2006“…RESULTS: UNIFORM PANEL: A total of 292 individuals determined to be generally representative of the regional distribution of the United States population and of areas of expertise or involvement in newborn screening provided a total of 3,949 evaluations of 84 conditions. …”
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354263por Baio, Jon, Wiggins, Lisa, Christensen, Deborah L., Maenner, Matthew J, Daniels, Julie, Warren, Zachary, Kurzius-Spencer, Margaret, Zahorodny, Walter, Robinson Rosenberg, Cordelia, White, Tiffany, Durkin, Maureen S., Imm, Pamela, Nikolaou, Loizos, Yeargin-Allsopp, Marshalyn, Lee, Li-Ching, Harrington, Rebecca, Lopez, Maya, Fitzgerald, Robert T., Hewitt, Amy, Pettygrove, Sydney, Constantino, John N., Vehorn, Alison, Shenouda, Josephine, Hall-Lande, Jennifer, Van Naarden Braun, Kim, Dowling, Nicole F.“…Because the ADDM sites do not provide a representative sample of the entire United States, the combined prevalence estimates presented in this report cannot be generalized to all children aged 8 years in the United States. …”
Publicado 2018
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354264“…METHOD: We draw on an ongoing Swedish study, with some Nordic references, using several data sources: (1) public statistics on treatment expenditures and purchases; (2) interviews with service users (n = 36) and their service providers (n = 23) on different market features; (3) an observation of a large public procurement process concluding framework agreements based on competitive tendering; (4) interviews with officials involved with steering of the system and procurement (n = 16); (5) a workshop on procurement in the Nordic countries (n = 11 participants); and (6) 77 interviews with professionals, managers, and elected representatives. RESULTS: We outline seven propositions that call for further research attention: public procurement, as regulated in the European Union, is not suitable for addiction treatment; marketization challenges democracy, equity, needs assessment, and treatment planning; marketization causes new accountability problems and idle monitoring; marketization causes fragmentation and obstructs coordination and continuity of care; marketization causes unification of services and favors big bureaucratically sophisticated providers; treatment professionals’ values are downplayed when a mistrust-based market logic replaces a trust- and needs-based logic; and marketization marginalizes treatment professionals and service users by limiting discretion. …”
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354265por Chen, Yifan, Wang, Zhenyu, Ding, Jian, Ming, Dongxu, Wang, Wenhui, Jiang, Zhaoning, Liu, Ling, Wang, Fenglai“…The six fiber-rich ingredients were defatted rice bran (DRB), sugar beet pulp (SBP), rice hull (RH), corn germ meal (CGM), SH and wheat bran (WB) and they were fed at represented 250, 270, 145, 250, 170 and 280 g/kg in the diet, respectively. …”
Publicado 2019
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354266por Chen, Jacqueline, Park, Kaitlyn, Uhm, Sun Young, Spinrad, Amelia, Uniya, Apurva, Pire-Smerkanich, Nancy, Pacifici, Eunjoo“…In phase I/II, phase II, and phase II/III CTs, females were represented at a higher levels than males by 8-20% (Table 1). …”
Publicado 2019
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354267por Chughtai, Talat, Parchani, Ashok, Strandvik, Gustav, Verma, Vishy, Arumugam, Suresh, El-Menyar, Ayman, Rizoli, Sandro, Al-Thani, Hassan“…Trauma is a leading cause of mortality and morbidity worldwide, and thus represents a great global health challenge. The World Health Organization (WHO) estimated that 9% of deaths in the world are the result of trauma.(1) In addition, approximately 100 million people are temporarily or permanently disabled every year.(2) The situation is no different in Qatar, and injury related morbidity and mortality is increasing in the entire region, with road traffic collisions (RTCs) being the most common mechanism.(1) It is well recognized now that trauma care provided in high-volume, dedicated, level-one trauma centers, improves outcome. …”
Publicado 2020
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354268por Almaghraby, Abdullah, Jaju, Alok, Ryan, Maura E, Rychlik, Karen, Habiby, Reema L, Brickman, Wendy“…The abnormal findings of brain MRI in the minority of isolated GH deficiency cases included pituitary hypoplasia, pituitary stalk agenesis, lack of the normal T1-weighted pituitary hyperintensity in the posterior part of the sella turcica, and the presence of a high-intensity signal at the infundibular level representing ectopic neurohypophysis. Traditionally, these brain and pituitary MRI images are obtained with the use of contrast material (gadolinium). …”
Publicado 2020
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354269por Duffy, J M N, Adamson, G D, Benson, E, Bhattacharya, S, Bhattacharya, S, Bofill, M, Brian, K, Collura, B, Curtis, C, Evers, J L H, Farquharson, R G, Fincham, A, Franik, S, Giudice, L C, Glanville, E, Hickey, M, Horne, A W, Hull, M L, Johnson, N P, Jordan, V, Khalaf, Y, Knijnenburg, J M L, Legro, R S, Lensen, S, MacKenzie, J, Mavrelos, D, Mol, B W, Morbeck, D E, Nagels, H, Ng, E H Y, Niederberger, C, Otter, A S, Puscasiu, L, Rautakallio-Hokkanen, S, Sadler, L, Sarris, I, Showell, M, Stewart, J, Strandell, A, Strawbridge, C, Vail, A, van Wely, M, Vercoe, M, Vuong, N L, Wang, A Y, Wang, R, Wilkinson, J, Wong, K, Wong, T Y, Farquhar, C M“…LIMITATIONS, REASONS FOR CAUTION: We used consensus development methods, which have inherent limitations, including the representativeness of the participant sample, methodological decisions informed by professional judgment and arbitrary consensus definitions. …”
Publicado 2020
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354270por Vergis, Nikhil, Phillips, Rachel, Cornelius, Victoria, Katsarou, Alexia, Youngstein, Taryn, Cook, Lucy, Willicombe, Michelle, Pilay, Clio, Shturova, Tina, Almonte, Melanie, Charania, Asad, Turner, Richard, Kon, Onn Min, Cooke, Graham, Thursz, Mark, Cherlin, Svetlana, Wason, James, Milojkovic, Dragana, Innes, Andew J., Cooper, Nichola“…Informed consent from patient or personal or professional representative. Agreement to abstain from sexual intercourse or use contraception that is >99% effective for all participants of childbearing potential for 42 days after the last dose of study drug. …”
Publicado 2021
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354271por Giacomini, E, Scotti, G M, Vanni, V S, Lazarevic, D, Makieva, S, Privitera, L, Signorelli, S, Cantone, L, Bollati, V, Murdica, V, Tonon, G, Papaleo, E, Candiani, M, Viganò, P“…This report is indeed the first to show that the transcriptome of UF-EVs correlates with the endometrial tissue transcriptome, that RNA signatures in UF-EVs change with endometrial status, and that UF-EVs could serve as a reservoir for potential less-invasive collection of receptivity markers. This article thus represents a step forward in the design of less-invasive approaches for real-time monitoring of endometrial status, necessary for advancing the field of reproductive medicine. …”
Publicado 2021
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354272por Bouchard, Patrice, Bousquet, Yves, Aalbu, Rolf L., Alonso-Zarazaga, Miguel A., Merkl, Ottó, Davies, Anthony E.“…A catalogue of 4122 nomenclaturally available genus-group names, representing 2307 valid genera (33 of which are extinct) and 761 valid subgenera, is given. …”
Publicado 2021
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354273por Demichelis, Roberta, Alvarado, Martha, Vasquez, Jule F, Delgado, Nancy, Gómez, Cynthia, Espinosa, Karla Adriana, Cooke, Ana, Milan, Andrea, Gomez-De Leon, Andres, Yu Ling, Lee-Tsai, Rosales, Daniel Estuardo, Cabrero Garcia, Alvaro, Amador, Lauro Fabian, Córdova-Ramírez, Carmina Alejandra, Murrieta-Álvarez, Iván, Solís-Poblano, Juan Carlos, Apodaca, Elia Ixel, Rangel-Patiño, Juan, Álvarez, Jose Luis, Arana, Luara, De la Peña-Celaya, Jose Antonio, Espitia, María Eugenia, Hernandez, Eleazar, Perez, Juan Manuel, González-Rivera, Rosa, García-Leyva, María Fernanda, Peña, Estefania, Tejeda Romero, Monica, Balderas-Delgado, Carolina, Cruz Rico, Jorge, Ruiz Arguelles, Guillermo, Gomez-Almaguer, David“…(Figure 1) 83 patients (13.1%) developed COVID-19 disease, the majority mild-moderate disease (54.2%), 27.7% severe disease and 18.1% critically ill; 27.7% required mechanical ventilation and 37.7% died from COVID-19 disease, representing 4.9% of the entire cohort. We identify as risk factors for COVID-19 disease the presence of active leukemia (newly diagnosed or relapsed) (OR 3.46 [95% CI: 2.16-5.5], p<0.001), high-risk leukemia (OR 1.63 [95% CI: 1.54-4.52], p<0.001) and being treated in a center were elective hospitalization was possible (OR 2.17 [95% CI 1.29-3.67], p=0.004). …”
Publicado 2020
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354274por Shapiro, Lauren C, Gali, Radhika, Thakkar, Astha, Gonzalez-Lugo, Jesus D, Bazarbachi, Abdul Hamid, Rahman, Shafia, Pradhan, Kith, Fehn, Karen, Abreu, Michelly, Kornblum, Noah, Gritsman, Kira, Goldfinger, Mendel, Shastri, Aditi, Mantzaris, Ioannis, Braunschweig, Ira, Halmos, Balazs, Verma, Amit, McCort, Margaret, Bachier-Rodriguez, Lizamarie, Sica, R. Alejandro“…Baseline characteristics and representative malignancies are listed in Table 1. Seventy pts (60%) received Pfizer, 36 pts (31%) Moderna, and 10 pts (9%) J&J. …”
Publicado 2021
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354275“…Final results were exponentiated to represent the percentage point difference in the odds of a given outcome for treatment groups relative to control groups. …”
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354276por Becker, Christian M, Bokor, Attila, Heikinheimo, Oskari, Horne, Andrew, Jansen, Femke, Kiesel, Ludwig, King, Kathleen, Kvaskoff, Marina, Nap, Annemiek, Petersen, Katrine, Saridogan, Ertan, Tomassetti, Carla, van Hanegem, Nehalennia, Vulliemoz, Nicolas, Vermeulen, Nathalie“…DISCLAIMER: This guideline represents the views of ESHRE, which were achieved after careful consideration of the scientific evidence available at the time of preparation. …”
Publicado 2022
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354277“…Mindfulness cognitive behavioral therapy (mbct), as a representative of the new generation of cognitive behavioral therapy, has achieved remarkable results in the treatment of anxiety and depression, obsessive-compulsive disorder, somatization disorder and chronic pain. …”
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354278por Kay, Alexander W, Ness, Tara, Verkuijl, Sabine E, Viney, Kerri, Brands, Annemieke, Masini, Tiziana, González Fernández, Lucia, Eisenhut, Michael, Detjen, Anne K, Mandalakas, Anna M, Steingart, Karen R, Takwoingi, Yemisi“…We summarized the frequency of Xpert Ultra trace results; trace represents detection of a very low quantity of Mycobacterium tuberculosis DNA. …”
Publicado 2022
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354279por Yang, Guang, Zhou, Siyuan, He, Haoqiang, Shen, Zinuo, Liu, Yongmei, Hu, Jun, Wang, Jie“…Li’s metabolomic study suggested that valine, leucine, isoleucine, and glycerol phospholipid metabolism could represent PBS syndrome (Zheng et al., 2022). Although some progress has been made in the understanding of PBS syndrome in CHD through the studies conducted, some issues still exist, such as a single-omics level, a lack of in-depth research, an inability to verify each other’s research results, and a lack of validation of research conclusions. …”
Publicado 2022
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354280por Coward, S, Benchimol, E I, Bernstein, C, Avina-Zubieta, J A, Bitton, A, Hracs, L, Jones, J, Kuenzig, E, Lu, L, Murthy, S K, Nugent, Z, Otley, A R, Panaccione, R, Pena-Sanchez, J -N, Singh, H, Targownik, L E, Windsor, J W, Kaplan, G“…Data were age and sex standardized to the matching year and aggregated into a representative sample of the Canadian population. Hospitalization rates were assessed as follows: 1. …”
Publicado 2023
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